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Human Leukocyte Antigen (HLA)-B, DRB1, and DQB1 Allotypes Associated with Disease and Protection of Trachoma Endemic Villagers
Investigative Ophthalmology and Visual Science, 04/15/09

Abbas M et al. - The data suggest that HLA-DRB 11 may offer protection from trichiasis in trachoma hyperendemic villages. Complete allotype identification and designation of its respective protective CD4+ T-cell antigens could provide a testable candidate vaccine for blindness prevention. Additionally, buccal swab DNA was sufficiently stable when acquired under harsh field conditions and stored long term in the freezer for low-resolution HLA typing.

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