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Comparative Toxicity of Preservatives on Immortalized Corneal and Conjunctival Epithelial Cells
Journal of Ocular Pharmacology and Therapeutics, 03/25/09
Epstein SP et al. - Generally, the order of decreasing toxicity at the most commonly used concentrations: Thi > BAK > Cbl > MP > SP = EDTA. Even at low concentration, these agents will cause some degree of ocular tissue damage.
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