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Mitochondrial Dysfunction and Glaucoma
Journal of Glaucoma, 02/27/09
Kong G et al. - This review details evidence to support the hypothesis that age-associated mitochondrial dysfunction renders RGCs susceptible to glaucomatous injury by reducing the energy available for repair processes and predisposing RGCs to apoptosis. Eliciting the role of mitochondria in glaucoma pathogenesis may uncover novel therapeutic targets for protecting the optic nerve and preventing vision loss in glaucoma.
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