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In the study, 50 patients were randomized to receive Durezol q.i.d. and 40 to receive Pred Forte eight times a day for an initial period of two weeks. At day 14, the Durezol patients showed a mean cell grade reduction of 2.1 and the Pred Forte group had a mean grade of 1.9, which confirmed the study’s endpoint of non-inferiority of Durezol compared to Pred Forte. The drugs were tapered over the remaining weeks, and, if any patient got worse at any point, he was removed from the study for more intensive treatment.


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