Pathologic Epithelial and Anterior Corneal Nerve Morphology in Early-Stage Congenital Aniridic Keratopathy

Ophthalmology, 05/03/2012

Early–stage aniridic keratopathy is characterized by the development of focal opacities in the basal epithelium, altered sub–basal nerves, infiltration of the central epithelium by dendritic cells, tear film instability, and increased corneal thickness and degradation of limbal palisade architecture. These findings may help to elucidate the pathogenesis of aniridic keratopathy.

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