Prostate cancer therapy may cause cataracts
Men who have undergone androgen deprivation therapy (ADT) have a 9% increased risk of developing cataracts. Results showed that those who underwent ADT tended to have an elevated risk for cataracts. A very modest elevation in the risk for cataract associated with androgen deprivation was found. It also seemed as if the relationship between androgen deprivation and cataract was slightly stronger among those patients without a history of cataract. If there is a causal relationship you would assume that in the patients with a prior history there are other more important driving factors. Among those patients without a history, orchiectomy showed the strongest association. Results showed that men who underwent orchiectomy had a 26% risk of developing cataracts compared with 9% for those on temporary ADT therapy.