Moxifloxacin Punctum Plug for Sustained Drug Delivery

Journal of Ocular Pharmacology and Therapeutics, 06/01/2012

Chee SP – The moxifloxacin–loaded punctum plug (MP) delivered and maintained moxifloxacin tear fluid concentrations at therapeutic levels above the MIC90 values for common susceptible conjunctivitis pathogens for 7 days. The MP also exhibited a favorable safety and tolerability profile and, hence, may be a viable alternative to topical antibiotic drops for the treatment of bacterial conjunctivitis.

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