Alterations of the p53 and PIK3CA/AKT/mTOR pathways in angiosarcomas
Cancer, 06/15/2012
Italiano A et al. – The current results indicated that angiosarcomas constitute a distinct subgroup among sarcomas with complex genomics. Although TP53 mutation and PTEN deletion are frequent in leiomyosarcoma (LMS) and undifferentiated pleomorphic sarcoma (UPS), these aberrations are rarely involved in the pathogenesis of angiosarcoma.



