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Cancer-testis antigens expressed in osteosarcoma identified by gene microarray correlate with a poor patient prognosis
Cancer, 09/08/2011
Zou C et al. – The combined use of an oligonucleotide microarray, a clinical database, and a tissue bank was useful for identifying molecular tumor markers. The frequent expression of melanoma antigen family A (MAGEA) and other cancer–testis antigens in osteosarcoma indicates that they may be useful as diagnostic markers and targets of immunotherapy that warrant further investigation.
