Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
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1 HPV genotypes and risk of precancer Cancer Epidemiology, Biomarkers & Prevention, May 21, 2013
2 Mutational analysis of BRCA1 and BRCA2 in hereditary breast and ovarian cancer families from Asturias Full Text BMC Cancer, May 21, 2013 Clinical Article
3 Poor Interobserver Reproducibility in the Diagnosis of High-grade Endometrial Carcinoma American Journal of Surgical Pathology , May 21, 2013 Review Article
4 Expression and Functional Pathway Analysis of Nuclear Receptor NR2F2 in Ovarian Cancer Journal of Clinical Endocrinology and Metabolism, May 21, 2013 Review Article
5 Hormonal and reproductive risk factors for sporadic microsatellite stable and unstable endometrial tumors Cancer Epidemiology, Biomarkers & Prevention, May 20, 2013
6 The size of the metastatic lymph node is an independent prognostic factor for the patients with cervical cancer treated by definitive radiotherapy Radiotherapy & Oncology, May 20, 2013 Review Article
7 HDR brachytherapy combined with interstitial hyperthermia in locally advanced cervical cancer patients initially treated with concomitant radiochemotherapy - a phase III study Radiotherapy & Oncology, May 20, 2013 Review Article
8 Bone Metastases in Endometrial Cancer: Report on 19 Patients and Review of the Medical Literature Gynecologic Oncology, May 20, 2013 Review Article
9 The use of CT findings to predict extent of tumor at primary surgery for ovarian cancer Gynecologic Oncology, May 20, 2013 Review Article
10 CpG island hypermethylation-associated silencing of microRNAs promotes human endometrial cancer Cancer Cell International, May 20, 2013 Review Article
11 Phase I dose-escalation study and population pharmacokinetic analysis of fixed dose rate gemcitabine plus carboplatin as second-line therapy in patients with ovarian cancer Gynecologic Oncology, May 20, 2013 Clinical Article
12 Loss of dok2 induces carboplatin resistance in ovarian cancer via suppression of apoptosis Gynecologic Oncology, May 20, 2013 Clinical Article
13 Phase II study of temsirolimus (CCI-779) in women with recurrent, unresectable, locally advanced or metastatic carcinoma of the cervix. a trial of the NCIC clinical trials group (NCIC CTG IND 199) Gynecologic Oncology, May 20, 2013 Clinical Article
14 Anthropometric Measures and the Risk of Endometrial Cancer, Overall and by Tumor Microsatellite Status and Histological Subtype American Journal of Epidemiology, May 17, 2013 Clinical Article
15 PI3K pathway dependencies in endometrioid endometrial cancer cell lines Clinical Cancer Research, May 17, 2013 Clinical Article
16 Molecular diagnosis of endometrial cancer from uterine aspirates International Journal of Cancer, May 17, 2013 Clinical Article
17 Preserved foods associated with increased risk of ovarian cancer Gynecologic Oncology, May 15, 2013 Clinical Article
18 A phase II study of modified dose-dense paclitaxel and every 4-week carboplatin for the treatment of advanced-stage primary epithelial ovarian, fallopian tube, or peritoneal carcinoma Cancer Chemotherapy and Pharmacology, May 15, 2013 Clinical Article
19 Risk of residual disease and invasive carcinoma in women treated for adenocarcinoma in situ of the cervix Gynecologic Oncology, May 15, 2013 Clinical Article
20 Impact of tumor size on survival in cancer of the cervix and validation of stage IIA1 and IIA2 subdivisions Gynecologic Oncology, May 15, 2013 Clinical Article
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 Human papillomavirus testing versus repeat cytology for triage of minor cytological cervical lesions Cochrane Reviews, April 1, 2013 Review Article
2 Prophylactic salpingectomy in premenopausal low-risk women for ovarian cancer: primum non nocere Gynecologic Oncology, April 9, 2013
3 Prognostic factors for stage III epithelial ovarian cancer treated with intraperitoneal chemotherapy: A Gynecologic Oncology Group Study Gynecologic Oncology, April 18, 2013
4 Tubulin-beta-III overexpression by uterine serous carcinomas is a marker for poor overall survival after platinum/taxane chemotherapy and sensitivity to epothilones Cancer, April 22, 2013
5 Early detection of ovarian cancer American Journal of Obstetrics and Gynecology, April 18, 2013 Review Article
6 Standard chemotherapy with or without bevacizumab in advanced ovarian cancer: quality-of-life outcomes from the International Collaboration on Ovarian Neoplasms (ICON7) phase 3 randomised trial The Lancet Oncology, March 14, 2013
7 High-grade vaginal intraepithelial neoplasia: can we be selective about who we treat? BJOG: An International Journal of Obstetrics and Gynaecology, April 4, 2013
8 Abagovomab as maintenance therapy in patients with epithelial ovarian cancer: a phase III trial of the AGO OVAR, COGI, GINECO, and GEICO--The Mimosa Study Journal of Clinical Oncology, March 15, 2013
9 The role of the fallopian tube in the origin of ovarian cancer American Journal of Obstetrics and Gynecology, April 18, 2013
10 Positive peritoneal cytology is highly predictive of prognosis and relapse patterns in stage III (FIGO 2009) endometrial cancer Gynecologic Oncology, April 26, 2013
11 Controversies of the Hormonal Conservative Treatment of Endometrial Cancer Gynecologic and Obstetric Investigation, April 1, 2013
12 An international assessment of ovarian cancer incidence and mortality Gynecologic Oncology, April 9, 2013
13 A Review of Dietary Prevention of Human Papillomavirus-Related Infection of the Cervix and Cervical Intraepithelial Neoplasia Nutrition and Cancer, April 1, 2013
14 Vascular endothelial growth factor (VEGF) improves the sensitivity of CA125 for differentiation of epithelial ovarian cancers from ovarian cysts Archives of Gynecology and Obstetrics, April 10, 2013
15 Controversies of the Hormonal Conservative Treatment of Endometrial Cancer Gynecologic and Obstetric Investigation, April 12, 2013 Review Article
16 Neoadjuvant chemotherapy prior to pelvic exenteration in patients with recurrent cervical cancer: Single institution experience Gynecologic Oncology, March 12, 2013
17 Fertility treatment and childhood cancer risk: A systematic meta-analysis Fertility and Sterility, April 8, 2013 Evidence Based Medicine Review Article
18 Outcome of stage IB2-IIB patients with bulky uterine cervical cancer who underwent neoadjuvant chemotherapy followed by radical hysterectomy International Journal of Clinical Oncology, April 19, 2013
19 Brachytherapy versus radical hysterectomy after external beam chemoradiation with gemcitabine plus cisplatin: a randomized, phase III study in IB2-IIB cervical cancer patients Annals of Oncology, April 29, 2013
20 Silencing of human papillomavirus (HPV) E6/E7 oncogene expression affects both the contents and amounts of extracellular microvesicles released from HPV-positive cancer cells International Journal of Cancer, April 1, 2013
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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