1Minimising critical organ irradiation in limited stage Hodgkin lymphoma: A dosimetric study of the benefit of involved node radiotherapyAnnals of Oncology  Full Text  Clinical Article
2Clinical relevance of flow cytometric immunophenotyping of the cerebrospinal fluid in patients with diffuse large B-cell lymphomaAnnals of Oncology  Full Text
3Multicenter, Phase II Study of Axitinib, a Selective Second-Generation Inhibitor of Vascular Endothelial Growth Factor Receptors 1, 2, 3, in Patients with Metastatic MelanomaClinical Cancer Research  Full Text  Clinical Article
4A Phase I Dose Esclation Study of Tivantinib in Adult Pts w Metastatic Solid TumorsClinical Cancer Research  Full Text  Clinical Article
5Phase I/II and Pharmacodynamic Study of Dovitinib (TKI258)-an Inhibitor of Fibroblast Growth Factor Receptors and VEGF Receptors-in Patients with Advanced MelanomaClinical Cancer Research  Full Text  Clinical Article
6Repeated and Aggressive Pulmonary Resections for Leiomyosarcoma Metastases Extends SurvivalAnnals of Thoracic Surgery  Full Text
7HIV envelope-mediated, CCR5/α4β7-dependent killing of CD4-negative γδ T cells which are lost during progression to AIDSBlood  Full Text
8Pam50 breast cancer subtyping by RT-QPCR and concordance with standard clinical molecular markersBMC Genomics  Full Text
9Breast vibro-acoustography: initial results show promiseBreast Cancer Research  Full Text
10Low levels of Stat5a protein in breast cancer are associated with tumor progression and unfavorable clinical outcomesBreast Cancer Research  Full Text
1MR spectroscopy shows precancerous breast changes in women with BRCA geneRadiological Society of North America News
2TSRI scientists find clues to cancer drug failureScripps Research Institute News
3Bans don't help smokers quitConcordia University Research News
4Cancer survival improvements vary by age, raceVanderbilt University Medical Center Research News
5UPMC CancerCenter first in world to treat patient with new Cyberknife MLC that shapes radiation to tumor, decreases treatment timeUPMC
6Healthy-looking prostate cells mask cancer-causing mutationsCancer Research UK News
7Combating 'chemo mouth'Fred Hutchinson Cancer Research Center News
8Reducing disparities in colon cancer through integrated careKaiser Permanente Health Research News
9Adjuvant VEGF inhibitors, sorafenib or sunitinib, do not improve outcomes in resected locally-advanced renal carcinomaEuropean Society for Medical Oncology News
10New nanodevice defeats drug resistanceMassachusetts Institute of Technology Research News

Show Me:

CHD7 associated with survival in pancreatic ductal adenocarcinoma patients receiving gemcitabine

As reported in Cancer Research, low CHD7 expression is associated with increased RFS and OS in pancreatic ductal adenocarcinoma patients receiving gemcitabine. There was no association between CHD7 expression and RFS or OS in patients who were not treated with gemcitabine.

Immunophenotype of small intestinal adenocarcinoma predicts survival

As reported in the European Journal of Obstetrics and Gynecology & Reproductive Biology, levels of the adipokine, apelin, are decreased in women with PCOS (n=45) compared to healthy controls. Apelin levels are positively correlated with BMI, insulin levels, triglycerides levels, free testosterone levels, the Ferriman-Gallwey score, and the HOMA index. Apelin levels are negatively correlated with HDL levels.

Loss of PTEN expression portends poor prognosis in IPMNs of the pancreas

As reported in Clinical Cancer Research, loss of PTEN in intraductal papillary mucinous neoplasms (IPMNs) of the pancreas (n=36) is associated with invasiveness and poor survival.

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Clinical Pearls

Clinical Pearl from Smartest DocMerkel cell carcinomas of the hand and upper extremity tend to have a higher overall survival rate.

Clinical Pearl from Smartest DocDiffusion-weighted magnetic resonance imaging is a new, fast and non-invasive technique to detect prostate cancer.

Clinical Pearl from Smartest DocKRAS wild-type metastatic colorectal cancer patients with high tumor integrin ?v?6 expression may benefit from abituzumab.

The Top Read Articles of 2014 are Now Available

Scouring thousands of peer-reviewed journals and popular press, Our Editors just released the Top Read Articles of the Year. See the Top Read List