Full Text Articles in Oncology

1Minimising critical organ irradiation in limited stage Hodgkin lymphoma: A dosimetric study of the benefit of involved node radiotherapyAnnals of Oncology, October 08, 2012  Full Text  Clinical Article
2Clinical relevance of flow cytometric immunophenotyping of the cerebrospinal fluid in patients with diffuse large B-cell lymphomaAnnals of Oncology, October 08, 2012  Full Text
3Multicenter, Phase II Study of Axitinib, a Selective Second-Generation Inhibitor of Vascular Endothelial Growth Factor Receptors 1, 2, 3, in Patients with Metastatic MelanomaClinical Cancer Research, October 08, 2012  Full Text  Clinical Article
4A Phase I Dose Esclation Study of Tivantinib in Adult Pts w Metastatic Solid TumorsClinical Cancer Research, October 08, 2012  Full Text  Clinical Article
5Phase I/II and Pharmacodynamic Study of Dovitinib (TKI258)-an Inhibitor of Fibroblast Growth Factor Receptors and VEGF Receptors-in Patients with Advanced MelanomaClinical Cancer Research, October 08, 2012  Full Text  Clinical Article
6Repeated and Aggressive Pulmonary Resections for Leiomyosarcoma Metastases Extends SurvivalAnnals of Thoracic Surgery, October 08, 2012  Full Text
7HIV envelope-mediated, CCR5/α4β7-dependent killing of CD4-negative γδ T cells which are lost during progression to AIDSBlood, October 08, 2012  Full Text
8Pam50 breast cancer subtyping by RT-QPCR and concordance with standard clinical molecular markersBMC Genomics, October 08, 2012  Full Text
9Breast vibro-acoustography: initial results show promiseBreast Cancer Research, October 08, 2012  Full Text
10Low levels of Stat5a protein in breast cancer are associated with tumor progression and unfavorable clinical outcomesBreast Cancer Research, October 08, 2012  Full Text
1Scientists trace genomic evolution of high-risk leukemiaSt. Jude Children's Research Hospital News, April 17, 2015
2Measuring treatment response proves to be a powerful tool for guiding leukemia treatmentSt. Jude Children's Research Hospital News, April 17, 2015
3Cancer drug target also essential for blood cell recoveryThe Walter and Eliza Hall Institute of Medical Research News, April 17, 2015
4To stop cancer: Block its messagesWeizmann Institute of Science News, April 17, 2015
5NHMRC funds better targeted cancer imaging and radiotherapyThe University of Sydney News, April 17, 2015
6Gene variant linked to smoking longer, getting lung cancer soonerWashington University School of Medicine in St. Louis News, April 17, 2015
7Tumor-only genetic sequencing may misguide cancer treatment in nearly half of all patients, study showsJohns Hopkins Medicine, April 17, 2015
8Functionality of drug resistance in melanoma decodedMedical University of Vienna, April 17, 2015
9Early use of palliative care in cancer improves patients lives, outcomes for caregiversNorris Cotton Cancer Center News, April 17, 2015
10Ovarian cancer: Genetic testing should be accessible to all women with the diseaseMcGill University Health Centre News, April 17, 2015

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Increased incidence of second primary cancers in patients with salivary gland tumors

As reported in JAMA—Otolaryngology-Head & Neck Surgery, patients with salivary gland tumors have an increased risk of second primary tumors and newly developed cancers. Specifically, the cumulative 2-, 5-, and 10-year rates for second primary cancers are 4.4%, 8.3%, and 12.4%, respectively. Similarly, the cumulative 2-, 5-, and 10-year rates for newly diagnosed cancers are 1.1%, 3.4%, and 10.5%, respectively.

CHD7 associated with survival in pancreatic ductal adenocarcinoma patients receiving gemcitabine

As reported in Cancer Research, low CHD7 expression is associated with increased RFS and OS in pancreatic ductal adenocarcinoma patients receiving gemcitabine. There was no association between CHD7 expression and RFS or OS in patients who were not treated with gemcitabine.

VPAC1 overexpression associated with colon cancer aggression

As reported in Tumor Biology, VPAC1 expression is increased in poorly differentiated compared to well-differentiated colon cancer. VPAC1 expression is also increased in the blood vessels and macrophages adjacent to colon cancer tissues compared to healthy tissues. The overexpression of VPAC1 is related to EGFR overexpression.

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Clinical Pearls

Clinical Pearl from Smartest DocHDACs suppress c-Jun expression in melanoma cells

Clinical Pearl from Smartest DocYoung cancer survivors have elevated risks of organic memory/brain disorders despite reduced cranial irradiation in children.

Clinical Pearl from Smartest DocCumulative adulthood UV exposure is associated with an increased risk of squamous cell and basal cell carcinoma.

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