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Oncology News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (142) Full Text Articles (6313) Focus on Pancreas
Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Management of Pancreatic Intraductal Papillary Mucinous Neoplasm in an Academic Hospital (2005-2010): What Follow-Up for Unoperated Patients Pancreas, May 21, 2013    Clinical Article

2 Risk for Mortality From Causes Other Than Pancreatic Cancer in Patients With Intraductal Papillary Mucinous Neoplasm of the Pancreas Pancreas, May 21, 2013    Clinical Article

3 Identification and impact of hepatitis B virus DNA and antigens in pancreatic cancer tissues and adjacent non-cancerous tissues Cancer Letters, May 21, 2013    Clinical Article

4 Prevalence and risk factors of extrapancreatic malignancies in a large cohort of patients with intraductal papillary mucinous neoplasm (IPMN) of the pancreas Annals of Oncology, May 21, 2013    Clinical Article

5 KRAS mutant allele-specific imbalance is associated with worse prognosis in pancreatic cancer and progression to undifferentiated carcinoma of the pancreas Modern Pathology, May 21, 2013    Clinical Article

6 Association of metformin use with cancer incidence and mortality: A meta-analysis Cancer Epidemiology, May 21, 2013    Review Article

7 Second-line treatment in advanced pancreatic cancer: a comprehensive analysis of published clinical trials Annals of Oncology, May 21, 2013    Clinical Article

8 Randomised, placebo-controlled, double-blind, parallel-group phase III study evaluating aflibercept in patients receiving first-line treatment with gemcitabine for metastatic pancreatic cancer European Journal of Cancer, May 21, 2013    Clinical Article

9 Meat-Related Mutagens and Pancreatic Cancer: null results from a clinic-based case-control study Cancer Epidemiology, Biomarkers & Prevention, May 21, 2013    Clinical Article

10 Biomarker results from the AVADO phase 3 trial of first-line bevacizumab plus docetaxel for HER2-negative metastatic breast cancer British Journal of Cancer, May 21, 2013    Clinical Article

11 Association between hepatitis B or hepatitis C virus infection and risk of pancreatic adenocarcinoma development: A systematic review and meta-analysis Pancreatology, May 21, 2013    Clinical Article

12 Pancreaticojejunostomy versus pancreaticogastrostomy reconstruction after pancreaticoduodenectomy for pancreatic or periampullary tumours: a multicentre randomised trial The Lancet Oncology, May 4, 2013

13 Biliary Findings Assist in Predicting Enlargement of Intraductal Papillary Mucinous Neoplasms of the Pancreas Clinical Gastroenterology and Hepatology , May 4, 2013    Clinical Article

14 A comparison of Ki-67 and mitotic count as prognostic markers for metastatic pancreatic and midgut neuroendocrine neoplasms British Journal of Cancer, May 4, 2013

15 Circulating tumor cells in pancreatic cancer patients: Methods of detection and clinical implications International Journal of Cancer, May 4, 2013    Clinical Article

16 Prognosis of Minimally Invasive Carcinoma Arising in Mucinous Cystic Neoplasms of the Pancreas American Journal of Surgical Pathology , May 4, 2013    Clinical Article

17 Laparoscopic Partial Sleeve Duodenectomy (PSD) for Nonampullary Duodenal Neoplasms: Avoiding a Whipple by Separating the Duodenum from the Pancreatic Head Pancreas, May 4, 2013    Review Article

18 Pancreatic Ductal Adenocarcinoma: Is There a Survival Difference for R1 Resections Versus Locally Advanced Unresectable Tumors? What Is a “True” R0 Resection? Annals of Surgery, April 17, 2013    Clinical Article

19 Gemcitabine Plus Capecitabine in Unselected Patients With Advanced Pancreatic Cancer Pancreas, April 17, 2013    Clinical Article

20 Metabolomic-derived novel cyst fluid biomarkers for pancreatic cysts: glucose and kynurenine Gastrointestinal Endoscopy, April 17, 2013    Clinical Article

21 A Novel Serum Metabolomics-Based Diagnostic Approach to Pancreatic Cancer Cancer Epidemiology, Biomarkers & Prevention, April 17, 2013    Review Article    Clinical Article

22 Aberrant expression of mucin core proteins and O-linked glycans associated with progression of pancreatic cancer Clinical Cancer Research, April 17, 2013

23 Overexpression of AIB1 correlates inversely with E-cadherin expression in pancreatic adenocarcinoma and may promote lymph node metastasis International Journal of Clinical Oncology, April 17, 2013

24 Randomized Phase III Study of Gemcitabine Plus S-1, S-1 Alone, or Gemcitabine Alone in Patients With Locally Advanced and Metastatic Pancreatic Cancer in Japan and Taiwan: GEST Study Journal of Clinical Oncology, April 17, 2013    Clinical Article

25 Identification and verification of transthyretin as a potential biomarker for pancreatic ductal adenocarcinoma Journal of Cancer Research & Clinical Oncology, April 17, 2013    Clinical Article

26 Erlotinib Prolongs Survival in Pancreatic Cancer by Blocking Gemcitabine-Induced MAPK Signals Cancer Research, April 17, 2013    Clinical Article

27 Factors Predictive of Adverse Events Associated with Endoscopic Ultrasound-Guided Fine Needle Aspiration of Pancreatic Solid Lesions Digestive Diseases and Sciences, March 31, 2013    Clinical Article

28 Risk of pancreatic cancer in breast cancer families from the Breast Cancer Family Registry Cancer Epidemiology, Biomarkers & Prevention, March 31, 2013    Clinical Article

29 PI3K/Akt/mTOR pathway inhibitors in the therapy of pancreatic neuroendocrine tumors Cancer Letters, March 31, 2013    Clinical Article
Exclusive Author Commentary

30 A phase II trial of nab-paclitaxel as second-line therapy in patients with advanced pancreatic cancer American Journal of Clinical Oncology, March 31, 2013    Clinical Article

31 53BP1 expression is a modifier of the prognostic value of lymph node ratio and CA 19--9 in pancreatic adenocarcinoma Full Text BMC Cancer, March 31, 2013    Clinical Article

32 KRAS mutation status is not predictive for objective response to anti-EGFR treatment with erlotinib in patients with advanced pancreatic cancer Journal of Gastroenterology, March 31, 2013    Review Article

33 Risk Factors for Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas: A Multicentre Case–Control Study The American Journal of Gastroenterology, March 14, 2013    Clinical Article

34 Aberrant expression of mucin core proteins and O-linked glycans associated with progression of pancreatic cancer Clinical Cancer Research, March 14, 2013

35 Gemcitabine-based or capecitabine-based chemoradiotherapy for locally advanced pancreatic cancer (SCALOP): a multicentre, randomised, phase 2 trial The Lancet Oncology, March 14, 2013    Clinical Article

36 Global, multicenter, randomized, phase II trial of gemcitabine and gemcitabine plus AGS-1C4D4 in patients with previously untreated, metastatic pancreatic cancer Annals of Oncology, March 14, 2013    Clinical Article

37 Inflammatory Plasma Markers and Pancreatic Cancer Risk: a Prospective Study of 5 U.S. Cohorts Cancer Epidemiology, Biomarkers & Prevention, March 14, 2013    Clinical Article

38 Comparative Effectiveness of Minimally Invasive and Open Distal Pancreatectomy for Ductal Adenocarcinoma Minimally Invasive Distal Pancreatectomy JAMA Surgery, March 14, 2013    Clinical Article

39 Percutaneous Cytologic Diagnosis of Solid Pseudopapillary Tumors of Pancreas in Children Journal of Pediatric Hematology/Oncology, February 25, 2013

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

Read the article summary

HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 Radiotherapy or tamoxifen after conserving surgery for breast cancers of excellent prognosis: British Association of Surgical Oncology (BASO) II trial European Journal of Cancer, April 2, 2013

2 R-CVP versus R-CHOP versus R-FM for the initial treatment of patients with advanced-stage follicular lymphoma: Results of the FOLL05 Trial conducted by the Fondazione Italiana Linfomi Journal of Clinical Oncology, April 1, 2013

3 Management of Newly Diagnosed Symptomatic Multiple Myeloma: Updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) Consensus Guidelines 2013 Mayo Clinic Proceedings, April 2, 2013    Clinical Guideline

4 Ipilimumab alone or in combination with radiotherapy in metastatic castration-resistant prostate cancer: results from an open-label, multicenter phase I/II study Annals of Oncology, April 3, 2013

5 Phase 2 study of dose-intense temozolomide in recurrent glioblastoma Neuro-Oncology, April 9, 2013

6 Estrogen plus progestin and breast cancer incidence and mortality in the Women's Health Initiative Observational Study Journal of the National Cancer Institute, April 4, 2013

7 Randomised phase 3 open-label trial of first-line treatment with gemcitabine in association with docetaxel or paclitaxel in women with metastatic breast cancer: a comparison of different schedules and treatments BMC Cancer, April 3, 2013    Free full text

8 Exemestane Versus Anastrozole in Postmenopausal Women With Early Breast Cancer: NCIC CTG MA.27--A Randomized Controlled Phase III Trial Journal of Clinical Oncology, February 11, 2013

9 Axillary dissection versus no axillary dissection in patients with sentinel-node micrometastases (IBCSG 23-01): a phase 3 randomised controlled trial The Lancet Oncology, March 12, 2013

10 Effect of low-dose tamoxifen after surgical excision of ductal intraepithelial neoplasia: results of a large retrospective monoinstitutional cohort study Annals of Oncology, April 1, 2013

11 High pretreatment serum lactate dehydrogenase level correlates with disease relapse and predicts an inferior outcome in locally advanced nasopharyngeal carcinoma European Journal of Cancer, April 5, 2013

12 Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2×2 factorial trial The Lancet Oncology, April 12, 2013

13 Intensive chemotherapy and immunotherapy in patients with newly diagnosed primary CNS lymphoma: CALGB 50202 (Alliance 50202) Journal of Clinical Oncology, April 15, 2013

14 Analysis in early stage triple-negative breast cancer treated with mastectomy without adjuvant radiotherapy: Patterns of failure and prognostic factors Cancer, April 11, 2013

15 Comparative effectiveness of three platinum-doublet chemotherapy regimens in elderly patients with advanced non-small cell lung cancer Cancer, April 10, 2013

16 Induction chemotherapy followed by concurrent chemoradiotherapy (sequential chemoradiotherapy) versus concurrent chemoradiotherapy alone in locally advanced head and neck cancer (PARADIGM): a randomised phase 3 trial The Lancet Oncology, February 15, 2013

17 Neoadjuvant chemotherapy with paclitaxel and everolimus in breast cancer patients with non-responsive tumours to epirubicin/cyclophosphamide (EC)±bevacizumab: Results of the randomised GeparQuinto study (GBG 44) European Journal of Cancer, April 5, 2013

18 Assessment of HER2 gene amplification in adenocarcinomas of the stomach or gastroesophageal junction in the INT-0116/SWOG9008 clinical trial Annals of Oncology, April 4, 2013

19 Antitumour activity of abiraterone acetate against metastatic castration-resistant prostate cancer progressing after docetaxel and enzalutamide (MDV3100) Annals of Oncology, April 16, 2013

20 R-CHOP therapy alone in limited stage diffuse large B-cell lymphoma British Journal of Haematology, March 1, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncologymore

Other Topics in Oncology

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