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Oncology News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (142) Full Text Articles (6313) Focus on Pancreas
Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Improving Hepatocellular Carcinoma Screening: Applying Lessons From Colorectal Cancer Screening Clinical Gastroenterology and Hepatology , May 18, 2013    Clinical Article

2 Expression of Apoptosis- and Vitamin D Pathway-Related Genes in Hepatocellular Carcinoma Digestion, May 18, 2013    Clinical Article

3 Presence of EpCAM-positive circulating tumor cells as biomarker for systemic disease strongly correlates to survival in patients with hepatocellular carcinoma International Journal of Cancer, May 18, 2013    Clinical Article

4 Dietary flavonoid, lignan and antioxidant capacity and risk of hepatocellular carcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC) Study International Journal of Cancer, May 18, 2013

5 Risk Stratification of Hepatocellular Carcinoma in Hepatitis B e Antigen-Negative Carriers by Combining Viral Biomarkers The Journal of Infectious Diseases, May 18, 2013    Clinical Article

6 A Pilot Study of Hepatic Arterial Infusion of Chemotherapy for Patients with Advanced Hepatocellular Carcinoma Who Have Failed Antiangiogenic Therapy Liver International, May 18, 2013    Review Article

7 Treatment strategy for recurrent hepatocellular carcinoma: Salvage transplantation, repeated resection or radiofrequency ablation Liver Transplantation, May 18, 2013    Review Article

8 Consumption of fish and meats and risk of hepatocellular carcinoma: the European Prospective Investigation into Cancer and Nutrition (EPIC) Annals of Oncology, May 18, 2013

9 Hepatocellular carcinoma in patients with chronic hepatitis C virus infection in the Asia-Pacific region Journal of Gastroenterology, May 18, 2013    Clinical Article

10 Assessment of response to sorafenib in advanced hepatocellular carcinoma using perfusion computed tomography: Results of a pilot study Digestive and Liver Diseases, May 18, 2013    Clinical Article

11 A risk for hepatocellular carcinoma still persists long-term after sustained virological response in patients with hepatitis C associated liver cirrhosis Clinical Infectious Diseases, May 18, 2013    Clinical Article

12 Role of antiviral therapy in the management of hepatocellular carcinoma Anti-Cancer Drugs, May 18, 2013    Clinical Article

13 Hypoxia induces epithelial-mesenchymal transition via activation of SNAI1 by hypoxia-inducible factor -1alpha in hepatocellular carcinoma Full Text BMC Cancer, May 18, 2013    Clinical Article

14 The efficacy of high-dose 3-dimensional conformal radiation therapy in patients with small hepatocellular carcinoma not eligible for other local modalities American Journal of Clinical Oncology, May 18, 2013    Clinical Article

15 Adjuvant Iodine-125 Brachytherapy for Hepatocellular Carcinoma after Complete Hepatectomy: A Randomized Controlled Trial PLOS ONE, May 18, 2013    Evidence Based Medicine

16 Positive glypican-3 expression in early hepatocellular carcinoma predicts recurrence after hepatectomy Journal of Gastroenterology, May 1, 2013    Clinical Article

17 A Phase II Randomized Dose Escalation Trial of Sorafenib in Patients With Advanced Hepatocellular Carcinoma Full Text The Oncologist, May 1, 2013    Clinical Article

18 Importance of screening for synchronous malignant neoplasms in patients with hepatocellular carcinoma: impact of FDG PET/CT Liver International, May 1, 2013    Clinical Article

19 α-Fetoprotein-to-Total Tumor Volume Ratio Predicts Post-operative Tumor Recurrence in Hepatocellular Carcinoma Journal of Gastrointestinal Surgery, May 1, 2013    Clinical Article

20 Temsirolimus combined with sorafenib in hepatocellular carcinoma: a phase I dose-finding trial with pharmacokinetic and biomarker correlates Annals of Oncology, May 1, 2013    Clinical Article

21 Pre-treatment C-Reactive Protein as a Prognostic Factor for Recurrence after Surgical Resection of Hepatocellular Carcinoma Anticancer Research, May 1, 2013    Clinical Article

22 Serum miR-483-5p as a potential biomarker to detect hepatocellular carcinoma Hepatology International, May 1, 2013    Review Article

23 Expression of Fibroblast Growth Factor 19 Is Associated with Recurrence and Poor Prognosis of Hepatocellular Carcinoma Digestive Diseases and Sciences, May 1, 2013    Clinical Article

24 Cortactin is a sensitive biomarker relative to the poor prognosis of human hepatocellular carcinoma Full Text World Journal of Surgical Oncology, May 1, 2013    Clinical Article

25 Increased Alpha-Fetoprotein Serum Level is Predictive for Survival and Recurrence of Hepatocellular Carcinoma in Non-Cirrhotic Livers Full Text Digestive Surgery, May 1, 2013    Clinical Article

26 Eradication of Hepatitis C Virus Infection and the Development of Hepatocellular Carcinoma: A Meta-analysis of Observational Studies Full Text Annals of Internal Medicine, April 14, 2013    Continuing Medical Education    Review Article

27 Liver Transplantation for Hepatocellular Carcinoma: An Appraisal of Current Controversies Liver Cancer, April 14, 2013    Review Article    Clinical Article

28 Survival Analysis of High-Intensity Focused Ultrasound Therapy Versus Radiofrequency Ablation in the Treatment of Recurrent Hepatocellular Carcinoma Annals of Surgery, April 14, 2013    Review Article    Clinical Article

29 Chemopreventive and Therapeutic Potential of Tea Polyphenols in Hepatocellular Cancer Nutrition and Cancer, April 14, 2013    Review Article

30 Transarterial embolization as neo-adjuvant therapy pre-transplantation in patients with hepatocellular carcinoma Liver International, April 14, 2013    Review Article

31 A Systematic Review of Radiofrequency Ablation versus Percutaneous Ethanol Injection for Small Hepatocellular Carcinoma up to 3 cm Journal of Gastroenterology and Hepatology, April 14, 2013    Evidence Based Medicine    Review Article    Clinical Article

32 Sequential Phase I and II Trials of Stereotactic Body Radiotherapy for Locally Advanced Hepatocellular Carcinoma Journal of Clinical Oncology, April 14, 2013    Clinical Article

33 Higher frequencies of GARP+ CTLA-4+ Foxp3+ T regulatory cells and myeloid-derived suppressor cells in hepatocellular carcinoma patients are associated with impaired T cell functionality Cancer Research, April 14, 2013    Clinical Article

34 Clinical parameters predictive of outcomes in sorafenib-treated patients with advanced hepatocellular carcinoma Liver International, April 14, 2013    Clinical Article

35 Safety and efficacy of adjuvant pegylated interferon therapy for metastatic tumor antigen 1-positive hepatocellular carcinoma Cancer, April 14, 2013    Clinical Article

36 Half-Life of Serum Alpha-Fetoprotein: An Early Prognostic Index of Recurrence and Survival After Hepatic Resection for Hepatocellular Carcinoma Annals of Surgery, March 28, 2013    Clinical Article

37 Statins and the risk of hepatocellular carcinoma in patients with hepatitis C virus infection Journal of Clinical Oncology, March 28, 2013    Clinical Article

38 Sorafenib in Elderly Patients with Advanced Hepatocellular Carcinoma: A Case Series Oncology, March 28, 2013    Clinical Article

39 Sorafenib combined with transarterial chemoembolization for the treatment of advanced hepatocellular carcinoma: a large-scale multicenter study of 222 patients Annals of Oncology, March 28, 2013

40 Prognotic impact of serum follistatin in patients with hepatocellular carcinoma. Journal of Gastroenterology and Hepatology, March 28, 2013    Clinical Article

41 The safety and efficacy of peginterferon plus ribavirin in hepatitis C patients concomitant with malignancy other than hepatocellular carcinoma: a multicenter study Hepatology International, March 28, 2013    Clinical Article

42 The Prognostic Value of Vascular Endothelial Growth Factor in Hepatocellular Carcinoma for Predicting Metastasis after Curative Resection Oncology, March 28, 2013    Clinical Article

43 Serum VEGF as a Tumor Marker in Patients with HCV-related Liver Cirrhosis and Hepatocellular Carcinoma Anticancer Research, March 28, 2013    Clinical Article

44 Suppression of actopaxin impairs hepatocellular carcinoma metastasis through modulation of cell migration and invasion Hepatology, March 28, 2013    Review Article

45 Efficacy, Safety, Pharmacokinetics, and Biomarkers of Cediranib Monotherapy in Advanced Hepatocellular Carcinoma: A Phase II Study Clinical Cancer Research, March 11, 2013    Clinical Article

46 A randomised phase II/III trial of 3-weekly cisplatin-based sequential transarterial chemoembolisation vs embolisation alone for hepatocellular carcinoma British Journal of Cancer, March 11, 2013    Clinical Article

47 The expression level of miR-18b in hepatocellular carcinoma is associated with the grade of malignancy and prognosis Full Text BMC Cancer, March 11, 2013    Clinical Article

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 Radiotherapy or tamoxifen after conserving surgery for breast cancers of excellent prognosis: British Association of Surgical Oncology (BASO) II trial European Journal of Cancer, April 2, 2013

2 R-CVP versus R-CHOP versus R-FM for the initial treatment of patients with advanced-stage follicular lymphoma: Results of the FOLL05 Trial conducted by the Fondazione Italiana Linfomi Journal of Clinical Oncology, April 1, 2013

3 Management of Newly Diagnosed Symptomatic Multiple Myeloma: Updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) Consensus Guidelines 2013 Mayo Clinic Proceedings, April 2, 2013    Clinical Guideline

4 Ipilimumab alone or in combination with radiotherapy in metastatic castration-resistant prostate cancer: results from an open-label, multicenter phase I/II study Annals of Oncology, April 3, 2013

5 Phase 2 study of dose-intense temozolomide in recurrent glioblastoma Neuro-Oncology, April 9, 2013

6 Estrogen plus progestin and breast cancer incidence and mortality in the Women's Health Initiative Observational Study Journal of the National Cancer Institute, April 4, 2013

7 Randomised phase 3 open-label trial of first-line treatment with gemcitabine in association with docetaxel or paclitaxel in women with metastatic breast cancer: a comparison of different schedules and treatments BMC Cancer, April 3, 2013    Free full text

8 Exemestane Versus Anastrozole in Postmenopausal Women With Early Breast Cancer: NCIC CTG MA.27--A Randomized Controlled Phase III Trial Journal of Clinical Oncology, February 11, 2013

9 Axillary dissection versus no axillary dissection in patients with sentinel-node micrometastases (IBCSG 23-01): a phase 3 randomised controlled trial The Lancet Oncology, March 12, 2013

10 Effect of low-dose tamoxifen after surgical excision of ductal intraepithelial neoplasia: results of a large retrospective monoinstitutional cohort study Annals of Oncology, April 1, 2013

11 High pretreatment serum lactate dehydrogenase level correlates with disease relapse and predicts an inferior outcome in locally advanced nasopharyngeal carcinoma European Journal of Cancer, April 5, 2013

12 Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2×2 factorial trial The Lancet Oncology, April 12, 2013

13 Intensive chemotherapy and immunotherapy in patients with newly diagnosed primary CNS lymphoma: CALGB 50202 (Alliance 50202) Journal of Clinical Oncology, April 15, 2013

14 Analysis in early stage triple-negative breast cancer treated with mastectomy without adjuvant radiotherapy: Patterns of failure and prognostic factors Cancer, April 11, 2013

15 Comparative effectiveness of three platinum-doublet chemotherapy regimens in elderly patients with advanced non-small cell lung cancer Cancer, April 10, 2013

16 Induction chemotherapy followed by concurrent chemoradiotherapy (sequential chemoradiotherapy) versus concurrent chemoradiotherapy alone in locally advanced head and neck cancer (PARADIGM): a randomised phase 3 trial The Lancet Oncology, February 15, 2013

17 Neoadjuvant chemotherapy with paclitaxel and everolimus in breast cancer patients with non-responsive tumours to epirubicin/cyclophosphamide (EC)±bevacizumab: Results of the randomised GeparQuinto study (GBG 44) European Journal of Cancer, April 5, 2013

18 Assessment of HER2 gene amplification in adenocarcinomas of the stomach or gastroesophageal junction in the INT-0116/SWOG9008 clinical trial Annals of Oncology, April 4, 2013

19 Antitumour activity of abiraterone acetate against metastatic castration-resistant prostate cancer progressing after docetaxel and enzalutamide (MDV3100) Annals of Oncology, April 16, 2013

20 R-CHOP therapy alone in limited stage diffuse large B-cell lymphoma British Journal of Haematology, March 1, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncologymore

Other Topics in Oncology

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