Oncology News & Articles

1 Clinical activity and safety of combination therapy with temsirolimus and bevacizumab for advanced melanoma: A Phase II trial (CTEP 7190/ Mel47) Clinical Cancer Research, May 11, 2013    Clinical Article

2 Phase II Trial of MEK Inhibitor Selumetinib (AZD6244, ARRY-142886) in Patients with BRAFV600E/K-Mutated Melanoma Clinical Cancer Research, May 11, 2013    Clinical Article

3 Randomized selection design trial evaluating CD8+-enriched versus unselected tumor-infiltrating lymphocytes for adoptive cell therapy for patients with melanoma Journal of Clinical Oncology, May 11, 2013

4 Phase I study of tremelimumab (CP-675 206) plus PF-3512676 (CPG 7909) in patients with melanoma or advanced solid tumours British Journal of Cancer, May 11, 2013    Clinical Article

5 Melanoma patients in a phase I clinic: molecular aberrations, targeted therapy and outcomes Annals of Oncology, May 11, 2013    Clinical Article

6 MERTK receptor tyrosine kinase is a therapeutic target in melanoma Full Text The Journal of Clinical Investigation, May 11, 2013    Clinical Article

7 Long-term survival and immunological parameters in metastatic melanoma patients who responded to ipilimumab 10mg/kg within an expanded access programme Cancer Immunology, Immunotherapy, May 11, 2013    Clinical Article

8 Rare BRAF mutations in melanoma patients: implications for molecular testing in clinical practice British Journal of Cancer, May 11, 2013    Review Article

9 Exposure to phototoxic NSAIDs and quinolones is associated with an increased risk of melanoma European Journal of Clinical Pharmacology, May 11, 2013    Clinical Article

10 Effects of BRAF inhibitors on Human Melanoma Tissue Before Treatment, Early During Treatment and on Progression Pigment Cell & Melanoma Research, May 11, 2013    Clinical Article

11 Efficacy and safety of retreatment with ipilimumab in patients with pretreated advanced melanoma who progressed after initially achieving disease control Clinical Cancer Research, April 24, 2013    Clinical Article

12 Pharmacodynamic Effects and Mechanisms of Resistance to Vemurafenib in Patients With Metastatic Melanoma Journal of Clinical Oncology, April 24, 2013    Clinical Article

13 Predicting Disease Progression After Regional Therapy for In-Transit Melanoma Disease Progression After Regional Therapy JAMA Surgery, April 24, 2013    Review Article

14 Combined blockade of TIM-3 and TIM-4 augments cancer vaccine efficacy against established melanomas Cancer Immunology, Immunotherapy, April 24, 2013    Clinical Article

15 Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2×2 factorial trial The Lancet Oncology, April 24, 2013    Clinical Article

16 Management of advanced non-melanoma skin cancers using helical tomotherapy Journal of the European Academy of Dermatology and Venereology, April 24, 2013    Clinical Article

17 Radiotherapy in the management of localized primary cutaneous B-cell lymphoma Leukemia and Lymphoma, April 24, 2013    Clinical Article

18 Increasing the therapeutic efficacy of docetaxel for cutaneous squamous cell carcinoma through the combined inhibition of phosphatidylinositol 3-kinase/AKT signalling and autophagy Clinical and Experimental Dermatology, April 24, 2013    Clinical Article

19 Low level of education is associated with later stage at diagnosis and reduced survival in cutaneous malignant melanoma: A nationwide population-based study in Sweden European Journal of Cancer, April 24, 2013    Clinical Article

20 P21-activated kinase 1 (pak1) as a therapeutic target in braf wild-type melanoma Journal of the National Cancer Institute, April 7, 2013

21 Prospective study of genital human papillomaviruses and non-melanoma skin cancer International Journal of Cancer, April 7, 2013

22 Disease Progression and Patient Survival Are Significantly Influenced by BRAF Protein Expression in Primary Melanoma British Journal of Dermatology, April 7, 2013    Clinical Article

23 Similar efficacy for phase I trials in comparison with DTIC for advanced malignant melanoma: an analysis of melanoma outcomes in CTEP-sponsored phase I trials 1995-2011 Melanoma Research, April 7, 2013    Clinical Article

24 Multicenter phase I trial of the mitogen-activated protein kinase 1/2 inhibitor BAY 86-9766 in patients with advanced cancer Clinical Cancer Research, April 7, 2013

25 p63 is an alternative p53 repressor in melanoma that confers chemoresistance and a poor prognosis Journal of Experimental Medicine, April 7, 2013    Clinical Article

26 Tyrosinase-related protein 1 mRNA expression in lymph node metastases predicts overall survival in high-risk melanoma patients British Journal of Cancer, April 7, 2013    Clinical Article

27 Assessment of clinical parameters associated with mutational status in metastatic malignant melanoma: a single-centre investigation of 141 patients British Journal of Dermatology, April 7, 2013    Clinical Article

28 Single-Center Experience With Ipilimumab in an Expanded Access Program for Patients With Pretreated Advanced Melanoma Journal of Immunotherapy, April 7, 2013    Clinical Article

29 Phase I/II study of pegylated arginine deiminase (ADI-PEG 20) in patients with advanced melanoma Investigational New Drugs, April 7, 2013    Clinical Article

30 Aspirin is associated with lower melanoma risk among postmenopausal Caucasian women Cancer, March 21, 2013    Clinical Article

31 Efficacy and safety of retreatment with ipilimumab in patients with pretreated advanced melanoma who progressed after initially achieving disease control Clinical Cancer Research, March 21, 2013    Clinical Article

32 Phase II trial of MEK inhibitor selumetinib (AZD6244) in patients with BRAFV600E/K-mutated melanoma Clinical Cancer Research, March 21, 2013

33 Analysis of Dermatologic Events in Vemurafenib-Treated Patients With Melanoma Full Text The Oncologist, March 21, 2013    Clinical Article

34 Effect of paclitaxel/carboplatin salvage chemotherapy in noncutaneous versus cutaneous metastatic melanoma Melanoma Research, March 21, 2013    Clinical Article

35 Experience in daily practice with ipilimumab for the treatment of patients with metastatic melanoma: an early increase in lymphocyte and eosinophil counts is associated with improved survival Annals of Oncology, March 21, 2013    Clinical Article

1 Radiotherapy or tamoxifen after conserving surgery for breast cancers of excellent prognosis: British Association of Surgical Oncology (BASO) II trial European Journal of Cancer, April 2, 2013

2 R-CVP versus R-CHOP versus R-FM for the initial treatment of patients with advanced-stage follicular lymphoma: Results of the FOLL05 Trial conducted by the Fondazione Italiana Linfomi Journal of Clinical Oncology, April 1, 2013

3 Management of Newly Diagnosed Symptomatic Multiple Myeloma: Updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) Consensus Guidelines 2013 Mayo Clinic Proceedings, April 2, 2013    Clinical Guideline

4 Ipilimumab alone or in combination with radiotherapy in metastatic castration-resistant prostate cancer: results from an open-label, multicenter phase I/II study Annals of Oncology, April 3, 2013

5 Phase 2 study of dose-intense temozolomide in recurrent glioblastoma Neuro-Oncology, April 9, 2013

6 Estrogen plus progestin and breast cancer incidence and mortality in the Women's Health Initiative Observational Study Journal of the National Cancer Institute, April 4, 2013

7 Randomised phase 3 open-label trial of first-line treatment with gemcitabine in association with docetaxel or paclitaxel in women with metastatic breast cancer: a comparison of different schedules and treatments BMC Cancer, April 3, 2013    Free full text

8 Exemestane Versus Anastrozole in Postmenopausal Women With Early Breast Cancer: NCIC CTG MA.27--A Randomized Controlled Phase III Trial Journal of Clinical Oncology, February 11, 2013

9 Axillary dissection versus no axillary dissection in patients with sentinel-node micrometastases (IBCSG 23-01): a phase 3 randomised controlled trial The Lancet Oncology, March 12, 2013

10 Effect of low-dose tamoxifen after surgical excision of ductal intraepithelial neoplasia: results of a large retrospective monoinstitutional cohort study Annals of Oncology, April 1, 2013

11 High pretreatment serum lactate dehydrogenase level correlates with disease relapse and predicts an inferior outcome in locally advanced nasopharyngeal carcinoma European Journal of Cancer, April 5, 2013

12 Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2×2 factorial trial The Lancet Oncology, April 12, 2013

13 Intensive chemotherapy and immunotherapy in patients with newly diagnosed primary CNS lymphoma: CALGB 50202 (Alliance 50202) Journal of Clinical Oncology, April 15, 2013

14 Analysis in early stage triple-negative breast cancer treated with mastectomy without adjuvant radiotherapy: Patterns of failure and prognostic factors Cancer, April 11, 2013

15 Comparative effectiveness of three platinum-doublet chemotherapy regimens in elderly patients with advanced non-small cell lung cancer Cancer, April 10, 2013

16 Induction chemotherapy followed by concurrent chemoradiotherapy (sequential chemoradiotherapy) versus concurrent chemoradiotherapy alone in locally advanced head and neck cancer (PARADIGM): a randomised phase 3 trial The Lancet Oncology, February 15, 2013

17 Neoadjuvant chemotherapy with paclitaxel and everolimus in breast cancer patients with non-responsive tumours to epirubicin/cyclophosphamide (EC)±bevacizumab: Results of the randomised GeparQuinto study (GBG 44) European Journal of Cancer, April 5, 2013

18 Assessment of HER2 gene amplification in adenocarcinomas of the stomach or gastroesophageal junction in the INT-0116/SWOG9008 clinical trial Annals of Oncology, April 4, 2013

19 Antitumour activity of abiraterone acetate against metastatic castration-resistant prostate cancer progressing after docetaxel and enzalutamide (MDV3100) Annals of Oncology, April 16, 2013

20 R-CHOP therapy alone in limited stage diffuse large B-cell lymphoma British Journal of Haematology, March 1, 2013