Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Oncology
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1 Antioxidant-mediated up-regulation of OGG1 via NRF2 induction is associated with inhibition of oxidative DNA damage in estrogen-induced breast cancer Full Text BMC Cancer, May 24, 2013 Clinical Article
2 Fork head box M1 is overexpressed in Helicobacter pylori-induced gastric carcinogenesis and is negatively regulated by hsa-miR-370 Molecular Cancer Research, May 20, 2013 Clinical Article
3 Methylation-Specific Digital Karyotyping of HPV16E6E7 expressing human keratinocytes identifies novel methylation events in cervical carcinogenesis The Journal of Pathology, May 16, 2013 Clinical Article
4 Deregulation of the histone demethylase JMJD2A is involved in human carcinogenesis through regulation of the G1/S transition Cancer Letters, May 15, 2013 Clinical Article
5 Ericifolin: a novel antitumor compound from allspice that silences androgen receptor in prostate cancer Carcinogenesis, May 14, 2013 Clinical Article
6 HBxAP{alpha}/Rsf-1-mediated HBx-hBubR1 interactions regulate the mitotic spindle checkpoint and chromosome instability Carcinogenesis, May 14, 2013 Clinical Article
7 Fried meat intake is a risk factor for lung adenocarcinoma in a prospective cohort of Chinese men and women in Singapore Carcinogenesis, May 14, 2013 Clinical Article
8 Is carcinoma a mesenchymal disease? The role of the stromal microenvironment in carcinogenesis Pathology, May 14, 2013 Review Article
9 Aerosol administration of phospho-sulindac inhibits lung tumorigenesis Molecular Cancer Therapeutics, May 13, 2013 Clinical Article
10 Metronomic chemotherapy following the maximum tolerated dose is an effective anti-tumour therapy affecting angiogenesis, tumour dissemination and cancer stem cells International Journal of Cancer, May 10, 2013 Clinical Article
11 Angiogenesis of Lung Cancer Utilizes Existing Blood Vessels Rather than Developing New Vessels Using Signals from Carcinogenesis Anticancer Research, May 10, 2013 Clinical Article
12 Decreased expression of BTG3 was linked to carcinogenesis, aggressiveness, and prognosis of ovarian carcinoma Tumor Biology, May 10, 2013 Clinical Article
13 Polymorphisms in xenobiotic metabolizing genes (EPHX1, NQO1 and PON1) in lymphoma susceptibility: a case control study Full Text BMC Cancer, May 9, 2013 Clinical Article
14 Dual modulation of JNK and Akt signaling pathways by chaetoglobosin K in human lung carcinoma and ras-transformed epithelial cells Investigational New Drugs, May 9, 2013 Clinical Article
15 The HER2-miR125a5p/miR125b loop in gastric and esophageal carcinogenesis Human Pathology, May 9, 2013 Clinical Article
16 Undifferentiated embryonic cell transcription factor-1 (UTF1) inhibits the growth of cervical cancer cells by transactivating p27Kip1 Carcinogenesis, May 7, 2013 Clinical Article
17 Depletion of 4E-BP1 and regulation of autophagy lead to YXM110-induced anti-cancer effects Carcinogenesis, May 6, 2013 Clinical Article
18 DNA polymerase {varepsilon} and {delta} exonuclease domain mutations in endometrial cancer Human Molecular Genetics, May 1, 2013 Clinical Article
19 Differential expression of histone deacetylases HDAC1, 2 and 3 in human breast cancer - overexpression of HDAC2 and HDAC3 is associated with clinicopathological indicators of disease progression Full Text BMC Cancer, May 1, 2013 Clinical Article
20 Role of C5b-9 complement complex and response gene to complement-32 (RGC-32) in cancer Immunologic Research, May 1, 2013 Clinical Article
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 Functional variants in TNFAIP8 associated with cervical cancer susceptibility and clinical outcomes Carcinogenesis, April 1, 2013
2 New Perspectives of Curcumin in Cancer Prevention Cancer Prevention Research, April 18, 2013 Review Article
3 Primary fallopian tube carcinoma European Journal of Obstetrics & Gynecology and Reproductive Biology, April 22, 2013 Review Article
4 Amiodarone and the risk of cancer Cancer, April 9, 2013
5 Effect of Three Decades of Screening Mammography on Breast-Cancer Incidence New England Journal of Medicine, March 14, 2013
6 Role of TGF-β signaling in curcumin-mediated inhibition of tumorigenicity of human lung cancer cells Journal of Cancer Research & Clinical Oncology, April 2, 2013
7 Silencing of human papillomavirus (HPV) E6/E7 oncogene expression affects both the contents and amounts of extracellular microvesicles released from HPV-positive cancer cells International Journal of Cancer, April 1, 2013
8 Tissue redox activity as a hallmark of carcinogenesis: from early to terminal stages of cancer Clinical Cancer Research, April 4, 2013
9 Management of Newly Diagnosed Symptomatic Multiple Myeloma: Updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) Consensus Guidelines 2013 Mayo Clinic Proceedings, April 9, 2013 Free full text Clinical Guideline
10 Infection and Cancer: Revaluation of the Hygiene Hypothesis Clinical Cancer Research, April 3, 2013
11 Sirtuin-1 Regulates Acinar-to-Ductal Metaplasia and Supports Cancer Cell Viability in Pancreatic Cancer Cancer Research, April 9, 2013
12 Mast cells and inflammation-associated colorectal carcinogenesis Seminars in Immunopathology , October 4, 2012
13 Strategy for detection of prostate cancer based on relation between prostate specific antigen at age 40-55 and long term risk of metastasis: case-control study British Medical Journal, April 23, 2013
14 Human papillomavirus testing versus repeat cytology for triage of minor cytological cervical lesions Cochrane Reviews, April 1, 2013 Review Article
15 Leukaemia update. Part 1: diagnosis and management British Medical Journal, April 9, 2013 Review Article
16 Polyubiquitination and proteasomal turnover controls the anti-apoptotic activity of Bcl-B Oncogene, April 11, 2013
17 Associations of CYP2E1 rs2031920 and rs3813867 polymorphisms with colorectal cancer risk: a systemic review and meta-analysis Tumor Biology, April 22, 2013 Evidence Based Medicine
18 DNA damage-independent apoptosis induced by curcumin in normal resting human T cells and leukaemic Jurkat cells Mutagenesis, April 1, 2013
19 Undifferentiated Embryonic Cell Transcription Factor-1 (UTF1) Inhibits the Growth of Cervical Cancer Cells by Transactivating p27Kip1 Carcinogenesis, April 3, 2013
20 25-hydroxyvitamin D and cancer risk in older adults Cancer Epidemiology, Biomarkers & Prevention, April 17, 2013
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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