Oncology - Carcinogenesis News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (1) Full Text Articles (87) Focus on Neurologic

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

121 The functional role of the novel biomarker karyopherin α2 (KPNA2) in cancer Cancer Letters, January 21, 2013 Clinical Article

122 Positive feedback loop and synergistic effects on promoting tumorgenesis between HIF-2 and SCD1 in clear cell renal cell carcinoma Cancer Science, January 21, 2013 Clinical Article

123 Does Microenvironment Contribute to the Etiology of Estrogen Receptor–Negative Breast Cancer Clinical Cancer Research, January 18, 2013 Clinical Article

124 CD146, a multi-functional molecule beyond adhesion Cancer Letters, January 17, 2013 Review Article Clinical Article

125 Polychlorinated biphenyls (PCBs) as initiating agents in hepatocellular carcinoma Cancer Letters, January 17, 2013 Review Article

126 Epigenetic reprogramming governs EcSOD expression during human mammary epithelial cell differentiation, tumorigenesis and metastasis Oncogene, January 16, 2013 Clinical Article

127 DNA damage associated with mitosis and cytokinesis failure Oncogene, January 16, 2013 Review Article

128 MicroRNA-18a modulates STAT3 activity through negative regulation of PIAS3 during gastric adenocarcinogenesis British Journal of Cancer, January 16, 2013 Clinical Article

129 PDCD4/miR-21 dysregulation in inflammatory bowel disease-associated carcinogenesis Virchows Archiv, January 15, 2013 Clinical Article

130 Global DNA hypomethylation in peripheral blood mononuclear cells as a biomarker of cancer risk Cancer Epidemiology, Biomarkers & Prevention, January 14, 2013

131 The role of cancer stem cells in cancer metastasis - New perspective and progress Cancer Epidemiology, January 11, 2013 Review Article

132 Visceral adiposity in gastrointestinal and hepatic carcinogenesis Cancer Letters, January 9, 2013 Clinical Article

133 Molecular Pathways Comparing the effects of drugs and T cells to effectively target oncogenes Clinical Cancer Research, January 8, 2013 Clinical Article

134 RhoB Differentially Controls Akt Function in Tumor Cells and Stromal Endothelial Cells during Breast Tumorigenesis Cancer Research, January 8, 2013 Clinical Article

135 Downregulation of tumor suppressor gene PML in uterine cervical carcinogenesis: Impact of human papillomavirus infection (HPV) Gynecologic Oncology, January 7, 2013 Clinical Article

136 53BP1 expression in sporadic and inherited ovarian carcinoma: Relationship to genetic status and clinical outcomes Gynecologic Oncology, January 7, 2013 Clinical Article

137 Cytoplasmic localization of alteration/deficiency in activation 3 (ADA3) predicts poor clinical outcome in breast cancer patients Breast Cancer Research and Treatment, January 7, 2013 Clinical Article

138 HuR cytoplasmic expression is associated with increased cyclin A expression and poor outcome with upper urinary tract urothelial carcinoma Full Text BMC Cancer, January 3, 2013

139 Osteosarcoma Phenotype Is Inhibited by 3,4-Methylenedioxy-β-nitrostyrene Sarcoma, January 3, 2013 Clinical Article

140 Avoiding room temperature storage and delayed cryopreservation provide better postthaw potency in hematopoietic progenitor cell grafts Transfusion, December 28, 2012

50 available pages First Previous 7 8 9 10 11 12 13 14 15 16 Next Last

Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 Functional variants in TNFAIP8 associated with cervical cancer susceptibility and clinical outcomes Carcinogenesis, April 1, 2013

2 New Perspectives of Curcumin in Cancer Prevention Cancer Prevention Research, April 18, 2013 Review Article

3 Primary fallopian tube carcinoma European Journal of Obstetrics & Gynecology and Reproductive Biology, April 22, 2013 Review Article

4 Amiodarone and the risk of cancer Cancer, April 9, 2013

5 Effect of Three Decades of Screening Mammography on Breast-Cancer Incidence New England Journal of Medicine, March 14, 2013

6 Role of TGF-β signaling in curcumin-mediated inhibition of tumorigenicity of human lung cancer cells Journal of Cancer Research & Clinical Oncology, April 2, 2013

7 Silencing of human papillomavirus (HPV) E6/E7 oncogene expression affects both the contents and amounts of extracellular microvesicles released from HPV-positive cancer cells International Journal of Cancer, April 1, 2013

8 Tissue redox activity as a hallmark of carcinogenesis: from early to terminal stages of cancer Clinical Cancer Research, April 4, 2013

9 Management of Newly Diagnosed Symptomatic Multiple Myeloma: Updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) Consensus Guidelines 2013 Mayo Clinic Proceedings, April 9, 2013 Free full text Clinical Guideline

10 Infection and Cancer: Revaluation of the Hygiene Hypothesis Clinical Cancer Research, April 3, 2013

11 Sirtuin-1 Regulates Acinar-to-Ductal Metaplasia and Supports Cancer Cell Viability in Pancreatic Cancer Cancer Research, April 9, 2013

12 Mast cells and inflammation-associated colorectal carcinogenesis Seminars in Immunopathology , October 4, 2012

13 Strategy for detection of prostate cancer based on relation between prostate specific antigen at age 40-55 and long term risk of metastasis: case-control study British Medical Journal, April 23, 2013

14 Human papillomavirus testing versus repeat cytology for triage of minor cytological cervical lesions Cochrane Reviews, April 1, 2013 Review Article

15 Leukaemia update. Part 1: diagnosis and management British Medical Journal, April 9, 2013 Review Article

16 Polyubiquitination and proteasomal turnover controls the anti-apoptotic activity of Bcl-B Oncogene, April 11, 2013

17 Associations of CYP2E1 rs2031920 and rs3813867 polymorphisms with colorectal cancer risk: a systemic review and meta-analysis Tumor Biology, April 22, 2013 Evidence Based Medicine

18 DNA damage-independent apoptosis induced by curcumin in normal resting human T cells and leukaemic Jurkat cells Mutagenesis, April 1, 2013

19 Undifferentiated Embryonic Cell Transcription Factor-1 (UTF1) Inhibits the Growth of Cervical Cancer Cells by Transactivating p27Kip1 Carcinogenesis, April 3, 2013

20 25-hydroxyvitamin D and cancer risk in older adults Cancer Epidemiology, Biomarkers & Prevention, April 17, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more

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Oncology - Carcinogenesis News & Articles

Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology