Oncology - Carcinogenesis News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (1) Full Text Articles (87) Focus on Urology

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

61 Translational regulation of RPA2 via internal ribosomal entry site and by eIF3a Carcinogenesis, March 29, 2013 Clinical Article

62 Identification of molecular alterations in gastrointestinal carcinomas and dysplastic hamartomas in Peutz-Jeghers syndrome Carcinogenesis, March 29, 2013 Clinical Article

63 c-Jun-mediated anticancer mechanisms of tylophorine Carcinogenesis, March 29, 2013 Clinical Article

64 The aldehyde dehydrogenase 2 (ALDH2) Glu504Lys polymorphism interacts with alcohol drinking in the risk of stomach cancer Carcinogenesis, March 27, 2013 Clinical Article

65 miR-371-5p down-regulates pre mRNA processing factor 4 homolog B (PRPF4B) and facilitates the G1/S transition in human hepatocellular carcinoma cells Cancer Letters, March 27, 2013 Clinical Article

66 Alcohol dehydrogenase, iron containing, 1 promoter hypermethylation associated with colorectal cancer differentiation Full Text BMC Cancer, March 26, 2013 Clinical Article

67 Association of Thyroid, Breast and Renal Cell Cancer: A Population-based Study of the Prevalence of Second Malignancies Annals of Surgical Oncology, March 25, 2013 Clinical Article

68 The link between infection and cancer: Tumor vasculature, free radicals, and drug delivery to tumors via the EPR effect Cancer Science, March 25, 2013 Clinical Article

69 Medullary Thyroid Carcinoma Endocrine Practice, March 22, 2013

70 Insulin-like Growth Factor Binding Protein 2 (IGFBP-2) Promotes Growth and Survival of Breast Epithelial Cells: Novel Regulation of the Estrogen Receptor. Endocrinology, March 22, 2013 Clinical Article

71 Hay Fever and Asthma as Markers of Atopic Immune Response and Risk of Colorectal Cancer in Three Large Cohort Studies Cancer Epidemiology, Biomarkers & Prevention, March 22, 2013 Review Article Clinical Article

72 Molecular features in arsenic-induced lung tumors Full Text Molecular Cancer, March 21, 2013 Review Article

73 Galectin-1 promotes lung cancer tumor metastasis by potentiating integrin {alpha}6{beta}4 and Notch1/Jagged2 signaling pathway Carcinogenesis, March 21, 2013 Clinical Article

74 Increased phosphorylation of histone H3 at serine 10 is involved in Epstein-Barr virus latent membrane protein-1-induced carcinogenesis of nasopharyngeal carcinoma Full Text BMC Cancer, March 20, 2013 Clinical Article

75 A novel splice variant of calcium and integrin-binding protein 1 mediates protein kinase D2-stimulated tumour growth by regulating angiogenesis Oncogene, March 20, 2013 Clinical Article

76 A cross-sectional analysis of lower genital tract intraepithelial neoplasia in immune-compromised women with an abnormal Pap Archives of Gynecology and Obstetrics, March 19, 2013 Clinical Article

77 Body mass index (BMI) and breast cancer: impact on tumor histopatologic features, cancer subtypes and recurrence rate in pre and postmenopausal women Gynecological Endocrinology, March 19, 2013 Clinical Article

78 The oncoprotein HBXIP up-regulates Lin28B via activating TFD to promote proliferation of breast cancer cells International Journal of Cancer, March 19, 2013 Clinical Article

79 MicroRNA-93 regulates NRF2 expression and is associated with breast carcinogenesis Carcinogenesis, March 19, 2013 Clinical Article

80 Corticotropin Releasing Hormone Is Correlated With Tumorigenesis of Gastric Cancer Cancer Investigation, March 19, 2013 Clinical Article

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Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 Functional variants in TNFAIP8 associated with cervical cancer susceptibility and clinical outcomes Carcinogenesis, April 1, 2013

2 New Perspectives of Curcumin in Cancer Prevention Cancer Prevention Research, April 18, 2013 Review Article

3 Primary fallopian tube carcinoma European Journal of Obstetrics & Gynecology and Reproductive Biology, April 22, 2013 Review Article

4 Amiodarone and the risk of cancer Cancer, April 9, 2013

5 Effect of Three Decades of Screening Mammography on Breast-Cancer Incidence New England Journal of Medicine, March 14, 2013

6 Role of TGF-β signaling in curcumin-mediated inhibition of tumorigenicity of human lung cancer cells Journal of Cancer Research & Clinical Oncology, April 2, 2013

7 Silencing of human papillomavirus (HPV) E6/E7 oncogene expression affects both the contents and amounts of extracellular microvesicles released from HPV-positive cancer cells International Journal of Cancer, April 1, 2013

8 Tissue redox activity as a hallmark of carcinogenesis: from early to terminal stages of cancer Clinical Cancer Research, April 4, 2013

9 Management of Newly Diagnosed Symptomatic Multiple Myeloma: Updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) Consensus Guidelines 2013 Mayo Clinic Proceedings, April 9, 2013 Free full text Clinical Guideline

10 Infection and Cancer: Revaluation of the Hygiene Hypothesis Clinical Cancer Research, April 3, 2013

11 Sirtuin-1 Regulates Acinar-to-Ductal Metaplasia and Supports Cancer Cell Viability in Pancreatic Cancer Cancer Research, April 9, 2013

12 Mast cells and inflammation-associated colorectal carcinogenesis Seminars in Immunopathology , October 4, 2012

13 Strategy for detection of prostate cancer based on relation between prostate specific antigen at age 40-55 and long term risk of metastasis: case-control study British Medical Journal, April 23, 2013

14 Human papillomavirus testing versus repeat cytology for triage of minor cytological cervical lesions Cochrane Reviews, April 1, 2013 Review Article

15 Leukaemia update. Part 1: diagnosis and management British Medical Journal, April 9, 2013 Review Article

16 Polyubiquitination and proteasomal turnover controls the anti-apoptotic activity of Bcl-B Oncogene, April 11, 2013

17 Associations of CYP2E1 rs2031920 and rs3813867 polymorphisms with colorectal cancer risk: a systemic review and meta-analysis Tumor Biology, April 22, 2013 Evidence Based Medicine

18 DNA damage-independent apoptosis induced by curcumin in normal resting human T cells and leukaemic Jurkat cells Mutagenesis, April 1, 2013

19 Undifferentiated Embryonic Cell Transcription Factor-1 (UTF1) Inhibits the Growth of Cervical Cancer Cells by Transactivating p27Kip1 Carcinogenesis, April 3, 2013

20 25-hydroxyvitamin D and cancer risk in older adults Cancer Epidemiology, Biomarkers & Prevention, April 17, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more

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Oncology - Carcinogenesis News & Articles

Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology