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Oncology - BMT/SCT News & Articles
Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Oncology
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Articles
Latest (4) Full Text Articles (175) Focus on Bone101 Clinical Guide to ABO Incompatible Allogeneic Stem Cell Transplantation Biology of Blood and Marrow Transplantation, April 12, 2013 Clinical Article
102 Application of five prognostic survival scores to primary myelofibrosis in 62 Brazilian patients Medical Oncology, April 12, 2013 Clinical Article
103 Comparison of characteristics of bacterial bloodstream infection between adult patients with allogenic and autologous hematopoietic stem cell transplantation Biology of Blood and Marrow Transplantation, April 11, 2013 Clinical Article
104 Allogeneic Hematopoietic Cell Transplantation in First Remission Abrogates Poor Outcomes Associated with High-Risk Pediatric Acute Myeloid Leukemia Biology of Blood and Marrow Transplantation, April 11, 2013 Clinical Article
105 Post-transplant T cell chimerism predicts graft versus host disease but not disease relapse in patients undergoing an alemtuzumab based reduced intensity conditioned allogeneic transplant Leukemia Research, April 11, 2013 Clinical Article
106 CMV reactivation is associated with a lower incidence of relapse after allo-SCT for CML Bone Marrow Transplantation, April 11, 2013 Clinical Article
107 Recent decrease in non-relapse mortality due to GVHD and infection after allogeneic hematopoietic cell transplantation in non-remission acute leukemia Bone Marrow Transplantation, April 11, 2013 Clinical Article
108 The impact of HLA-E polymorphisms on relapse following allogeneic hematopoietic stem cell transplantation Leukemia Research, April 11, 2013 Review Article
109 Molecular monitoring and stepwise preemptive therapy for Epstein-Barr virus viremia after allogeneic stem cell transplantation American Journal of Hematology, April 10, 2013 Clinical Article
110 PEDF Promotes Self-Renewal of Limbal Stem Cell and Accelerates Corneal Epithelial Wound Healing Stem Cells, April 9, 2013 Clinical Article
111 Allo-HSCT for acute leukemia of ambiguous lineage in adults: the comparison between standard conditioning and intensified conditioning regimens Annals of Hematology, April 9, 2013 Clinical Article
112 A case-control study of bronchiolitis obliterans syndrome following allogeneic hematopoietic stem cell transplantation Transplant International, April 9, 2013 Clinical Article
113 Predicting the Clinical Outcome of Allogeneic Hematopoietic Stem Cell Transplantation: The Long and Winding Road toward Validated Immune Biomarkers Frontiers in Immunology, April 9, 2013 Review Article
114 Essential role of sox2 for the establishment and maintenance of the germ cell line Stem Cells, April 8, 2013 Clinical Article
115 Disease-causing Mitochondrial Heteroplasmy Segregated within Induced Pluripotent Stem Cell Clones Derived from A MELAS Patient Stem Cells, April 8, 2013 Clinical Article
116 Alterations in the cellular immune compartment of patients treated with third-party mesenchymal stromal cells following allogeneic hematopoietic stem-cell transplantation Stem Cells, April 8, 2013 Clinical Article
117 Anti-thymocyte globulins for post-transplant graft-versus-host disease prophylaxis--A systematic review and meta-analysis Critical Reviews in Oncology/Hematology, April 8, 2013 Evidence Based Medicine Review Article
118 Lung histology predicts outcome of bronchiolitis obliterans syndrome after hematopoietic stem cell transplantation Biology of Blood and Marrow Transplantation, April 8, 2013 Clinical Article
119 Busulfan Dose Intensity and Outcomes in Reduced Intensity Allogeneic Peripheral Blood Stem Cell Transplantation for MDS/AML Biology of Blood and Marrow Transplantation, April 8, 2013 Clinical Article
120 Favorable outcome in a child with EBV-negative aggressive NK cell leukemia International Journal of Hematology, April 8, 2013 Clinical Article
Clinical Pearls in Oncology
- The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
- A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
- In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease
Highlights in Oncology
VEGFR-1 is a prognostic marker for HCC
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryHCC risk increased in patients with AIDS
As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryRAB25 is a prognostic marker for ovarian cancer
As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summaryMost Popular Oncology Articles
Last month's top read Top Articles of 20121 Allogeneic hematopoietic cell transplantation for consolidation of VGPR or CR for newly diagnosed multiple myeloma Bone Marrow Transplantation, April 3, 2013
2 Disease status and stem cell source impact on the results of reduced intensity conditioning transplant for Hodgkin lymphoma: a retrospective study from the French Society of Bone Marrow Graft Transplantation and Cellular Therapy Haematologica, April 4, 2013 Free full text Review Article
3 Donor lymphocyte infusion for relapsed hematological malignancies after allogeneic hematopoietic cell transplantation: prognostic relevance of the initial CD3+ T cell dose Biology of Blood and Marrow Transplantation, April 1, 2013
4 Clinical Guide to ABO Incompatible Allogeneic Stem Cell Transplantation Biology of Blood and Marrow Transplantation, April 12, 2013
5 Somatic hypermutation analysis in follicular lymphoma provides evidence suggesting bidirectional cell migration between lymph node and bone marrow during disease progression and relapse Haematologica, April 15, 2013 Free full text Review Article
6 Graft-Versus-Host Disease and Graft-Versus-Tumor Effects After Allogeneic Hematopoietic Cell Transplantation Journal of Clinical Oncology, March 19, 2013
7 Comparison of outcomes after two standards-of-care RIC regimens and two different graft sources (FB2A2-PBSC vs dUCB-TCF) for allogeneic stem cells transplantation (allo-SCT) in adults with haematological diseases: a single centre analysis Biology of Blood and Marrow Transplantation, April 2, 2013
8 Increase of suicide and accidental death after hematopoietic stem cell transplantation Cancer, March 25, 2013
9 Allogeneic Hematopoietic Cell Transplantation for Fanconi Anemia in Patients With Pretransplantation Cytogenetic Abnormalities, Myelodysplastic Syndrome, or Acute Leukemia Journal of Clinical Oncology, April 5, 2013
10 Autologous retransplantation for patients with recurrent multiple myeloma Cancer, April 15, 2013
11 Application of five prognostic survival scores to primary myelofibrosis in 62 Brazilian patients Medical Oncology, April 12, 2013
12 Three-Dimensional Virtual Bone Bank System Workflow for Structural Bone Allograft Selection: A Technical Report Sarcoma, April 19, 2013
13 Busulfan Dose Intensity and Outcomes in Reduced Intensity Allogeneic Peripheral Blood Stem Cell Transplantation for MDS/AML Biology of Blood and Marrow Transplantation, April 8, 2013
14 Impact of pre-transplant marrow blasts on survival of allogeneic stem cell transplantation in adult acute myeloid leukemia International Journal of Hematology, April 3, 2013
15 Mitigating effects of hUCB-MSCs on the hematopoietic syndrome resulting from total body irradiation Experimental Hematology, April 15, 2013
16 Characteristics of chronic GVHD after cord blood transplantation Bone Marrow Transplantation, April 18, 2013
17 Autologous Umbilical Cord Blood (UCB) Infusion Followed by Oral Docosahexanoic Acid (DHA) and Vitamin D (VitD) Supplementation for C-Peptide Preservation in Children with Type 1 Diabetes (T1D) Biology of Blood and Marrow Transplantation, April 24, 2013
18 The hematopoietic cell transplantation-specific comorbidity index (HCT-CI) is an outcome predictor for partially matched related donor transplantation American Journal of Hematology, April 1, 2013
19 Determining the optimal time for bortezomib-based induction chemotherapy followed by autologous hematopoietic stem cell transplant in the treatment of multiple myeloma Chinese Journal of Cancer Research, April 16, 2013 Free full text
20 A case-control study of bronchiolitis obliterans syndrome following allogeneic hematopoietic stem cell transplantation Transplant International, April 9, 2013
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
Other Topics in Oncology
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