Oncology - BMT/SCT News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (2) Full Text Articles (175) Focus on Pancreas

Ranked, sorted, and summarized by MDLinx editors from the latest literature

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661 Ultra-short course sirolimus contributes to effective GVHD prophylaxis after reduced-intensity allogeneic hematopoietic cell transplantation Bone Marrow Transplantation, May 2, 2012

662 Durable remission with salvage second autotransplants in patients with multiple myeloma Cancer, April 30, 2012

663 Clinical predictors of cognitive function in adults treated with hematopoietic cell transplantation Cancer, April 27, 2012

664 Prevalence of sarcopenia and relevance of body composition, physiological function, fatigue, and health-related quality of life in patients before allogeneic hematopoietic stem cell transplantation Supportive Care in Cancer, April 20, 2012

665 Next generation sequencing fails to identify human virus sequences in cutaneous squamous cell carcinoma International Journal of Cancer, April 19, 2012

666 A randomized phase 2 trial of a preparative regimen of bortezomib, high-dose melphalan, arsenic trioxide, and ascorbic acid Cancer, April 18, 2012 Clinical Article

667 Prognostic impact of discordant results from cytogenetics and flow cytometry in patients with acute myeloid leukemia undergoing hematopoietic cell transplantation Cancer, April 17, 2012

668 Distinct signal transduction abnormalities and erythropoietin response in bone marrow hematopoietic cell subpopulations of myelodysplastic syndrome patients Full Text Clinical Cancer Research, April 13, 2012

669 Use of eltrombopag, a thrombopoietin receptor agonist, in post-transplantation thrombocytopenia American Journal of Hematology, April 12, 2012

670 Patients quality of life after allogeneic haematopoietic stem cell transplantation: mixed-methods study European Journal of Cancer Care, April 12, 2012

671 Incidence and treatment strategy for disseminated adenovirus disease after haploidentical stem cell transplantation Annals of Hematology, April 12, 2012

672 The EuroChimerism concept for a standardized approach to chimerism analysis after allogeneic stem cell transplantation Leukemia, April 12, 2012

673 Low-dose Cytarabine plus Aclarubicin for Patients with Previously Untreated Acute Myeloid Leukemia or High-risk Myelodysplastic Syndrome Ineligible for Standard-dose Cytarabine plus Anthracycline Anticancer Research, April 11, 2012 Clinical Article

674 Thiotepa and melphalan based single, tandem, and triple high dose therapy and autologous stem cell transplantation for high risk neuroblastoma Pediatric Blood & Cancer, April 11, 2012 Clinical Article

675 Anaesthesia in patients after transplantation AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie, April 11, 2012

676 Rituximab, gemcitabine, cisplatin, and dexamethasone in patients with refractory or relapsed aggressive B-cell lymphoma Medical Oncology, April 10, 2012 Clinical Article

677 Successful treatment by donor lymphocyte infusion of adult T-cell leukemia/lymphoma relapse following allogeneic hematopoietic stem cell transplantation International Journal of Hematology, April 10, 2012

678 Next generation sequencing fails to identify human virus sequences in cutaneous squamous cell carcinoma International Journal of Cancer, April 9, 2012

679 Intensified therapy followed by autologous stem-cell transplantation (ASCT) versus conventional therapy as first-line treatment of follicular lymphoma: a meta-analysis Hematological Oncology, April 9, 2012 Evidence Based Medicine

680 Outcome of patients activating an unrelated donor search: the impact of transplant with reduced intensity conditioning in a large cohort of consecutive high-risk patients Leukemia, April 6, 2012

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Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 Allogeneic hematopoietic cell transplantation for consolidation of VGPR or CR for newly diagnosed multiple myeloma Bone Marrow Transplantation, April 3, 2013

2 Disease status and stem cell source impact on the results of reduced intensity conditioning transplant for Hodgkin lymphoma: a retrospective study from the French Society of Bone Marrow Graft Transplantation and Cellular Therapy Haematologica, April 4, 2013 Free full text Review Article

3 Donor lymphocyte infusion for relapsed hematological malignancies after allogeneic hematopoietic cell transplantation: prognostic relevance of the initial CD3+ T cell dose Biology of Blood and Marrow Transplantation, April 1, 2013

4 Clinical Guide to ABO Incompatible Allogeneic Stem Cell Transplantation Biology of Blood and Marrow Transplantation, April 12, 2013

5 Somatic hypermutation analysis in follicular lymphoma provides evidence suggesting bidirectional cell migration between lymph node and bone marrow during disease progression and relapse Haematologica, April 15, 2013 Free full text Review Article

6 Graft-Versus-Host Disease and Graft-Versus-Tumor Effects After Allogeneic Hematopoietic Cell Transplantation Journal of Clinical Oncology, March 19, 2013

7 Comparison of outcomes after two standards-of-care RIC regimens and two different graft sources (FB2A2-PBSC vs dUCB-TCF) for allogeneic stem cells transplantation (allo-SCT) in adults with haematological diseases: a single centre analysis Biology of Blood and Marrow Transplantation, April 2, 2013

8 Increase of suicide and accidental death after hematopoietic stem cell transplantation Cancer, March 25, 2013

9 Allogeneic Hematopoietic Cell Transplantation for Fanconi Anemia in Patients With Pretransplantation Cytogenetic Abnormalities, Myelodysplastic Syndrome, or Acute Leukemia Journal of Clinical Oncology, April 5, 2013

10 Autologous retransplantation for patients with recurrent multiple myeloma Cancer, April 15, 2013

11 Application of five prognostic survival scores to primary myelofibrosis in 62 Brazilian patients Medical Oncology, April 12, 2013

12 Three-Dimensional Virtual Bone Bank System Workflow for Structural Bone Allograft Selection: A Technical Report Sarcoma, April 19, 2013

13 Busulfan Dose Intensity and Outcomes in Reduced Intensity Allogeneic Peripheral Blood Stem Cell Transplantation for MDS/AML Biology of Blood and Marrow Transplantation, April 8, 2013

14 Impact of pre-transplant marrow blasts on survival of allogeneic stem cell transplantation in adult acute myeloid leukemia International Journal of Hematology, April 3, 2013

15 Mitigating effects of hUCB-MSCs on the hematopoietic syndrome resulting from total body irradiation Experimental Hematology, April 15, 2013

16 Characteristics of chronic GVHD after cord blood transplantation Bone Marrow Transplantation, April 18, 2013

17 Autologous Umbilical Cord Blood (UCB) Infusion Followed by Oral Docosahexanoic Acid (DHA) and Vitamin D (VitD) Supplementation for C-Peptide Preservation in Children with Type 1 Diabetes (T1D) Biology of Blood and Marrow Transplantation, April 24, 2013

18 The hematopoietic cell transplantation-specific comorbidity index (HCT-CI) is an outcome predictor for partially matched related donor transplantation American Journal of Hematology, April 1, 2013

19 Determining the optimal time for bortezomib-based induction chemotherapy followed by autologous hematopoietic stem cell transplant in the treatment of multiple myeloma Chinese Journal of Cancer Research, April 16, 2013 Free full text

20 A case-control study of bronchiolitis obliterans syndrome following allogeneic hematopoietic stem cell transplantation Transplant International, April 9, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more

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Oncology - BMT/SCT News & Articles

Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology