Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Oncology
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D Scott Cunningham MD, PhD
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1 Benefits and adverse events in younger versus older patients receiving neoadjuvant chemotherapy for osteosarcoma: findings from a meta-analysis Journal of Clinical Oncology, May 17, 2013 Review Article
2 Association, among very-low-birthweight neonates, between red blood cell transfusions in the week after birth and severe intraventricular hemorrhage Transfusion, May 17, 2013 Review Article
3 Feasibility of an outpatient HLA haploidentical stem cell transplantation program in children using a reduced-intensity conditioning regimen and CD3-CD19 depletion Hematology, May 17, 2013 Clinical Article
4 Outcome of childhood acute Lymphoblastic leukemia in Egyptian children: A challenge for limited health resource countries Hematology, May 17, 2013 Clinical Article
5 Outcome of childhood acute Lymphoblastic leukemia in Egyptian children: A challenge for limited health resource countries Hematology, May 16, 2013 Clinical Article
6 Treatment With Topotecan Plus Cyclophosphamide in Children With First Relapse of Neuroblastoma Pediatric Blood & Cancer, May 16, 2013 Clinical Article
7 Phase I trial, pharmacokinetics, and pharmacodynamics of vandetanib and dasatinib in children with newly diagnosed diffuse intrinsic pontine glioma Clinical Cancer Research, May 15, 2013 Clinical Article
8 Fractional anisotropy of the optic radiations is associated with visual acuity loss in optic pathway gliomas of neurofibromatosis type 1 Neuro-Oncology, May 15, 2013 Clinical Article
9 TGF-β1 suppression of microRNA-450b-5p expression: a novel mechanism for blocking myogenic differentiation of rhabdomyosarcoma Oncogene, May 15, 2013 Clinical Article
10 The potential effect of gender in CYP1A1 and GSTM1 genotype-specific associations with pediatric brain tumor Tumor Biology, May 15, 2013 Clinical Article
11 BK viremia precedes hemorrhagic cystitis in children undergoing allogeneic hematopoietic stem cell transplantation Biology of Blood and Marrow Transplantation, May 15, 2013 Clinical Article
12 Late mortality after hematopoietic SCT for a childhood malignancy Bone Marrow Transplantation, May 15, 2013 Clinical Article
13 Chemotherapy in pediatric bone and soft-tissue sarcomas Current Orthopaedic Practice , May 15, 2013 Review Article
14 A multicenter, first-in-pediatrics, phase 1, pharmacokinetic and pharmacodynamic study of ridaforolimus in patients with refractory solid tumors Clinical Cancer Research, May 14, 2013
15 Physical exercise training interventions for children and young adults during and after treatment for childhood cancer Cochrane Reviews, May 14, 2013 Clinical Article
16 Familial risk of childhood cancer and tumors in the Li-Fraumeni spectrum in the Utah population database: Implications for genetic evaluation in pediatric practice International Journal of Cancer, May 14, 2013 Clinical Article
17 Regulation of Target Genes of PAX3-FOXO1 in Alveolar Rhabdomyosarcoma Anticancer Research, May 14, 2013 Clinical Article
18 The evaluation of protein Z levels of children with acute lymphoblastic leukaemia during induction therapy Blood Coagulation & Fibrinolysis, May 14, 2013 Clinical Article
19 Descriptive epidemiology of ependymal tumours in the United States British Journal of Cancer, May 13, 2013 Clinical Article
20 Hemolytic Anemia After Placement of an Intraluminal Pulmonary Artery Band Annals of Thoracic Surgery, May 13, 2013
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 Fertility treatment and childhood cancer risk: A systematic meta-analysis Fertility and Sterility, April 8, 2013 Evidence Based Medicine Review Article
2 Childhood leukaemia close to high-voltage power lines – the Geocap study, 2002–2007 British Journal of Cancer, April 17, 2013 Review Article
3 Low Serum Lipocalin Levels in Patients With Iron Deficiency Anemia Journal of Pediatric Hematology/Oncology, April 1, 2013
4 What is the relevance of Ikaros gene deletions as prognostic marker in pediatric Philadelphia negative B-cell precursor acute lymphoblastic leukemia? Haematologica, April 15, 2013 Free full text
5 Exposure to pesticides and the risk of childhood brain tumors Cancer Causes and Control, April 10, 2013
6 Tumor origin and growth pattern at diagnosis and surgical hypothalamic damage predict obesity in pediatric craniopharyngioma Journal of Neuro-Oncology, April 16, 2013
7 Evaluation of memory impairment in aging adult survivors of childhood acute lymphoblastic leukemia treated with cranial radiotherapy Journal of the National Cancer Institute, April 18, 2013
8 Long term follow-up of survivors of childhood cancer: summary of updated SIGN guidance British Medical Journal, April 9, 2013 Clinical Guideline
9 Outcome of infants and young children with newly diagnosed ependymoma treated on the Head Start III prospective clinical trial Journal of Neuro-Oncology, March 25, 2013
10 A 10-year follow up of reproductive function in women treated for childhood cancer Reproductive BioMedicine Online, April 26, 2013
11 Allogeneic Hematopoietic Cell Transplantation in First Remission Abrogates Poor Outcomes Associated with High-Risk Pediatric Acute Myeloid Leukemia Biology of Blood and Marrow Transplantation, April 11, 2013
12
Thoracoscopic resection of computed tomography-localized lung nodules in children
Journal of Pediatric Surgery, April 23, 2013
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13 A comparative analysis of paediatric dose-finding trials of molecularly targeted agent with adults trials European Journal of Cancer, April 2, 2013
14 Bone marrow evaluation for pediatric patients International Journal of Laboratory Hematology, April 26, 2013 Review Article
15 FDG PET/CT in children and adolescents with lymphoma Pediatric Radiology, March 25, 2013 Review Article
16 Salvage allogeneic hematopoietic SCT for primary graft failure in children Bone Marrow Transplantation, March 27, 2013 Review Article
17 Moderate Aplastic Anemia in Children: Preliminary Outcomes for Treatment Versus Observation From a Single-Institutional Experience Journal of Pediatric Hematology/Oncology, March 4, 2013
18 Cardiac Magnetic Resonance Imaging in the Evaluation of the Late Effects of Anthracyclines Among Long-Term Survivors of Childhood Cancer JACC - Journal of the American College of Cardiology, April 5, 2013
19 Transfusion-associated hyperkalemic cardiac arrest in pediatric patients receiving massive transfusion Transfusion, April 19, 2013
20 FoxG1 Interacts with Bmi1 to Regulate Self-Renewal and Tumorigenicity of Medulloblastoma Stem Cells Stem Cells, April 22, 2013
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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