Peds Heme/Oncology News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (5) Full Text Articles (216) Focus on Pediatric

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

121 Antioxidant Levels at Diagnosis in Childhood Acute Lymphoblastic Leukemia The Indian Journal of Pediatrics, April 11, 2013 Review Article

122 Exposure to pesticides and the risk of childhood brain tumors Cancer Causes and Control, April 10, 2013

123 Long term follow-up of survivors of childhood cancer: summary of updated SIGN guidance British Medical Journal, April 9, 2013 Clinical Guideline

124 Fertility treatment and childhood cancer risk: A systematic meta-analysis Fertility and Sterility, April 8, 2013 Evidence Based Medicine Review Article

125 Effects of Daily Iron Supplementation in 2- to 5-Year-Old Children: Systematic Review and Meta-analysis Pediatrics, April 8, 2013 Evidence Based Medicine Review Article

126 Distinct Effects of Ligand-Induced PDGFRα and PDGFRβ Signaling in the Human Rhabdomyosarcoma Tumor Cell and Stroma Cell Compartments Cancer Research, April 8, 2013 Clinical Article

127 Repiphysis prosthesis for limb preservation in pediatric patients with bone cancer: a literature review Orthopaedic Nursing, April 8, 2013 Review Article

128 Cannabinoid CB2 receptor gene (CNR2) polymorphism is associated with chronic childhood immune thrombocytopenia in Egypt Blood Coagulation & Fibrinolysis, April 8, 2013 Review Article

129 Cardiac Magnetic Resonance Imaging in the Evaluation of the Late Effects of Anthracyclines Among Long-Term Survivors of Childhood Cancer JACC - Journal of the American College of Cardiology, April 5, 2013 Clinical Article

130 Asymmetric Dimethylarginine levels in Children with Sickle Cell Disease and its Correlation to Tricuspid Regurgitant Jet Velocity European Journal of Haematology, April 5, 2013 Clinical Article

131 Supra- and infratentorial pediatric ependymomas differ significantly in NeuN, p75 and GFAP expression Journal of Neuro-Oncology, April 5, 2013 Clinical Article

132 MPL Baltimore Mutation and Thrombocytosis: Case Report and Literature Review Journal of Pediatric Hematology/Oncology, April 5, 2013 Review Article

133 Evaluation of a bedside device to assess the activated partial thromboplastin time for heparin monitoring in infants Blood Coagulation & Fibrinolysis, April 5, 2013 Clinical Article

134 Hydroa vacciniforme-like cutaneous T-cell lymphoma: Clinicopathologic and immunohistochemical study of 12 cases Journal of the American Academy of Dermatology, April 4, 2013

135 Stem Cell Transplantation in Primary Myelofibrosis of Childhood Journal of Pediatric Hematology/Oncology, April 4, 2013

136 Hematological and hemorheological determinants of resting and exercise-induced hemoglobin oxygen desaturation in children with sickle cell disease Full Text Haematologica, April 3, 2013 Clinical Article

137 SNF5 Controls Transcription via SWI/SNF and RNAPII Recruitment Molecular Cancer Research, April 3, 2013 Clinical Article

138 The effects of repetitive haemarthrosis on postural balance in children with haemophilia Haemophilia, April 3, 2013 Clinical Article

139 Assessment of individual dose utilization vs. physician prescribing recommendations for recombinant activated factor VII (rFVIIa) in paediatric and adult patients with congenital haemophilia and alloantibody inhibitors (CHwI): the Dosing Observational Study in Hemophilia (DOSE) Haemophilia, April 3, 2013 Clinical Article

140 Pediatric Extranodal Marginal Zone B-Cell Lymphoma Presenting as Amyloidosis in Minor Salivary Glands: A Case Report and Review of the Literature Journal of Pediatric Hematology/Oncology, April 3, 2013 Review Article

50 available pages First Previous 7 8 9 10 11 12 13 14 15 16 Next Last

Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 Fertility treatment and childhood cancer risk: A systematic meta-analysis Fertility and Sterility, April 8, 2013 Evidence Based Medicine Review Article

2 Childhood leukaemia close to high-voltage power lines – the Geocap study, 2002–2007 British Journal of Cancer, April 17, 2013 Review Article

3 Low Serum Lipocalin Levels in Patients With Iron Deficiency Anemia Journal of Pediatric Hematology/Oncology, April 1, 2013

4 What is the relevance of Ikaros gene deletions as prognostic marker in pediatric Philadelphia negative B-cell precursor acute lymphoblastic leukemia? Haematologica, April 15, 2013 Free full text

5 Exposure to pesticides and the risk of childhood brain tumors Cancer Causes and Control, April 10, 2013

6 Tumor origin and growth pattern at diagnosis and surgical hypothalamic damage predict obesity in pediatric craniopharyngioma Journal of Neuro-Oncology, April 16, 2013

7 Evaluation of memory impairment in aging adult survivors of childhood acute lymphoblastic leukemia treated with cranial radiotherapy Journal of the National Cancer Institute, April 18, 2013

8 Long term follow-up of survivors of childhood cancer: summary of updated SIGN guidance British Medical Journal, April 9, 2013 Clinical Guideline

9 Outcome of infants and young children with newly diagnosed ependymoma treated on the Head Start III prospective clinical trial Journal of Neuro-Oncology, March 25, 2013

10 A 10-year follow up of reproductive function in women treated for childhood cancer Reproductive BioMedicine Online, April 26, 2013

11 Allogeneic Hematopoietic Cell Transplantation in First Remission Abrogates Poor Outcomes Associated with High-Risk Pediatric Acute Myeloid Leukemia Biology of Blood and Marrow Transplantation, April 11, 2013

12 Thoracoscopic resection of computed tomography-localized lung nodules in children Journal of Pediatric Surgery, April 23, 2013 Review Article
Exclusive Author Commentary

13 A comparative analysis of paediatric dose-finding trials of molecularly targeted agent with adults trials European Journal of Cancer, April 2, 2013

14 Bone marrow evaluation for pediatric patients International Journal of Laboratory Hematology, April 26, 2013 Review Article

15 FDG PET/CT in children and adolescents with lymphoma Pediatric Radiology, March 25, 2013 Review Article

16 Salvage allogeneic hematopoietic SCT for primary graft failure in children Bone Marrow Transplantation, March 27, 2013 Review Article

17 Moderate Aplastic Anemia in Children: Preliminary Outcomes for Treatment Versus Observation From a Single-Institutional Experience Journal of Pediatric Hematology/Oncology, March 4, 2013

18 Cardiac Magnetic Resonance Imaging in the Evaluation of the Late Effects of Anthracyclines Among Long-Term Survivors of Childhood Cancer JACC - Journal of the American College of Cardiology, April 5, 2013

19 Transfusion-associated hyperkalemic cardiac arrest in pediatric patients receiving massive transfusion Transfusion, April 19, 2013

20 FoxG1 Interacts with Bmi1 to Regulate Self-Renewal and Tumorigenicity of Medulloblastoma Stem Cells Stem Cells, April 22, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more

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Peds Heme/Oncology News & Articles

Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology