Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Oncology
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D Scott Cunningham MD, PhD
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61 Childhood leukemia and lymphoma: time trends and factors affecting survival in five Southern and Eastern European Cancer Registries Cancer Causes and Control, May 7, 2013 Review Article
62 A comparative analysis of paediatric dose-finding trials of molecularly targeted agent with adults trials European Journal of Cancer, May 6, 2013 Clinical Article
63 Intensity-modulated radiotherapy (IMRT) in pediatric low-grade glioma Cancer, May 6, 2013 Clinical Article
64 Symptomatic Epidural Compression in Infants With Neuroblastoma: A Single-Center Experience With 5 Cases Journal of Pediatric Hematology/Oncology, May 6, 2013
65 Physical Performance of Nontransplanted Childhood ALL Survivors is Comparable to Healthy Controls Journal of Pediatric Hematology/Oncology, May 6, 2013 Clinical Article
66 Methylation of the TERT promoter and risk stratification of childhood brain tumours: an integrative genomic and molecular study The Lancet Oncology, May 3, 2013
67 Safety and activity of crizotinib for paediatric patients with refractory solid tumours or anaplastic large-cell lymphoma: a Children's Oncology Group phase 1 consortium study The Lancet Oncology, May 3, 2013 Clinical Article
68 Multiple pilomatricomas with somatic CTNNB1 mutations in children with constitutive mismatch repair deficiency Genes, Chromosomes and Cancer, May 3, 2013 Clinical Article
69 MicroRNAs and Recent Insights into Pediatric Ovarian Cancers Frontiers in Oncology, May 3, 2013 Clinical Article
70 LGR5 is Expressed by Ewing Sarcoma and Potentiates Wnt/β-Catenin Signaling Frontiers in Oncology, May 3, 2013 Clinical Article
71 Advanced Targeted, Cell and Gene-Therapy Approaches for Pediatric Hematological Malignancies: Results and Future Perspectives Frontiers in Oncology, May 3, 2013 Clinical Article
72 Diffuse Leptomeningeal Neuroepithelial Tumor: 9 Pediatric Cases With Chromosome 1p/19q Deletion Status and IDH1 (R132H) Immunohistochemistry American Journal of Surgical Pathology , May 3, 2013 Clinical Article
73 Biology of Childhood Acute Lymphoblastic Leukemia Journal of Pediatric Hematology/Oncology, May 3, 2013 Review Article
74 Bereaved Parents and Siblings Offer Advice to Health Care Providers and Researchers Journal of Pediatric Hematology/Oncology, May 3, 2013 Clinical Article
75 Survival of pediatric patients after relapsed osteosarcoma: The St. Jude Childrens Research Hospital experience Cancer, May 2, 2013
76 NUP98-NSD1 gene fusion and its related gene expression signature are strongly associated with a poor prognosis in pediatric acute myeloid leukemia Genes, Chromosomes and Cancer, May 2, 2013 Clinical Article
77 Sickle Cell-related Bone Marrow Complications: The Utility of Diffusion-weighted Magnetic Resonance Imaging Journal of Pediatric Hematology/Oncology, May 2, 2013 Clinical Article
78 Outcome and toxicity using helical tomotherapy for craniospinal irradiation in pediatric medulloblastoma Clinical and Translational Oncology, May 2, 2013 Clinical Article
79 Conventional and Advanced MRI Features of Pediatric Intracranial Tumors: Supratentorial Tumors American Journal of Roentgenology, May 2, 2013 Review Article
80 The molecular and cell biology of pediatric low-grade gliomas Oncogene, May 1, 2013 Review Article Clinical Article
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 Fertility treatment and childhood cancer risk: A systematic meta-analysis Fertility and Sterility, April 8, 2013 Evidence Based Medicine Review Article
2 Childhood leukaemia close to high-voltage power lines – the Geocap study, 2002–2007 British Journal of Cancer, April 17, 2013 Review Article
3 Low Serum Lipocalin Levels in Patients With Iron Deficiency Anemia Journal of Pediatric Hematology/Oncology, April 1, 2013
4 What is the relevance of Ikaros gene deletions as prognostic marker in pediatric Philadelphia negative B-cell precursor acute lymphoblastic leukemia? Haematologica, April 15, 2013 Free full text
5 Exposure to pesticides and the risk of childhood brain tumors Cancer Causes and Control, April 10, 2013
6 Tumor origin and growth pattern at diagnosis and surgical hypothalamic damage predict obesity in pediatric craniopharyngioma Journal of Neuro-Oncology, April 16, 2013
7 Evaluation of memory impairment in aging adult survivors of childhood acute lymphoblastic leukemia treated with cranial radiotherapy Journal of the National Cancer Institute, April 18, 2013
8 Long term follow-up of survivors of childhood cancer: summary of updated SIGN guidance British Medical Journal, April 9, 2013 Clinical Guideline
9 Outcome of infants and young children with newly diagnosed ependymoma treated on the Head Start III prospective clinical trial Journal of Neuro-Oncology, March 25, 2013
10 A 10-year follow up of reproductive function in women treated for childhood cancer Reproductive BioMedicine Online, April 26, 2013
11 Allogeneic Hematopoietic Cell Transplantation in First Remission Abrogates Poor Outcomes Associated with High-Risk Pediatric Acute Myeloid Leukemia Biology of Blood and Marrow Transplantation, April 11, 2013
12
Thoracoscopic resection of computed tomography-localized lung nodules in children
Journal of Pediatric Surgery, April 23, 2013
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13 A comparative analysis of paediatric dose-finding trials of molecularly targeted agent with adults trials European Journal of Cancer, April 2, 2013
14 Bone marrow evaluation for pediatric patients International Journal of Laboratory Hematology, April 26, 2013 Review Article
15 FDG PET/CT in children and adolescents with lymphoma Pediatric Radiology, March 25, 2013 Review Article
16 Salvage allogeneic hematopoietic SCT for primary graft failure in children Bone Marrow Transplantation, March 27, 2013 Review Article
17 Moderate Aplastic Anemia in Children: Preliminary Outcomes for Treatment Versus Observation From a Single-Institutional Experience Journal of Pediatric Hematology/Oncology, March 4, 2013
18 Cardiac Magnetic Resonance Imaging in the Evaluation of the Late Effects of Anthracyclines Among Long-Term Survivors of Childhood Cancer JACC - Journal of the American College of Cardiology, April 5, 2013
19 Transfusion-associated hyperkalemic cardiac arrest in pediatric patients receiving massive transfusion Transfusion, April 19, 2013
20 FoxG1 Interacts with Bmi1 to Regulate Self-Renewal and Tumorigenicity of Medulloblastoma Stem Cells Stem Cells, April 22, 2013
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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