Oncology - Diagnostics/Radiology News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (5) Full Text Articles (304) Focus on Hematology

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

661 Optical imaging correlates with magnetic resonance imaging breast density and reveals composition changes during neoadjuvant chemotherapy Breast Cancer Research, February 26, 2013 Clinical Article

662 Online advertising by three commercial breast imaging services: Message takeout and effectiveness The Breast, February 26, 2013 Clinical Article

663 Hormone metabolism genes and mammographic density in Singapore Chinese women Cancer Epidemiology, Biomarkers & Prevention, February 26, 2013 Clinical Article

664 Effect of inhibition of the FGFR-MAPK signaling pathway on the development of ocular toxicities Cancer Treatment Reviews, February 26, 2013 Review Article

665 Insights into the field carcinogenesis of ovarian cancer based on the nanocytology of endocervical and endometrial epithelial cells International Journal of Cancer, February 26, 2013 Clinical Article

666 Adjuvant treatment of resected nonsmall cell lung cancer: state of the art and new potential developments Current Opinion in Oncology, February 26, 2013 Clinical Article

667 Telomerase inhibition by non-nucleosidic compound BIBR1532 causes rapid cell death in pre-B acute lymphoblastic leukemia cells Leukemia and Lymphoma, February 26, 2013 Clinical Article

668 SALL4 and SF-1 Are Sensitive and Specific Markers for Distinguishing Granulosa Cell Tumors From Yolk Sac Tumors International Journal of Surgical Pathology, February 26, 2013 Clinical Article

669 Morphologic MRI features, diffusion tensor imaging and radiation dosimetric analysis to differentiate pseudo-progression from early tumor progression Journal of Neuro-Oncology, February 26, 2013 Clinical Article

670 Tumor location and nature of lymphatic vessels are key determinants of cancer metastasis Clinical and Experimental Metastasis, February 26, 2013 Clinical Article

671 Prognostic Significance of Combinations of RNA-Dependent Protein Kinase and EphA2 Biomarkers for NSCLC Journal of Thoracic Oncology, February 26, 2013 Clinical Article

672 Women's views on overdiagnosis in breast cancer screening: a qualitative study British Medical Journal, February 26, 2013 Evidence Based Medicine

673 Bilateral Contrast-enhanced Dual-Energy Digital Mammography: Feasibility and Comparison with Conventional Digital Mammography and MR Imaging in Women with Known Breast Carcinoma Radiology, February 25, 2013 Review Article Clinical Article

674 Magnetic resonance imaging as a predictor of pathologic response in patients treated with neoadjuvant systemic treatment for operable breast cancer Cancer, February 25, 2013 Clinical Article

675 The Added Role of MR Imaging in Treatment Stratification of Patients with Gynecologic Malignancies: What the Radiologist Needs to Know Radiology, February 25, 2013 Review Article

676 Focused Ultrasound Delivers Targeted Immune Cells To Metastatic Brain Tumors Cancer Research, February 25, 2013 Clinical Article

677 Identifying patients with undetected renal tract cancer in primary care: An independent and external validation of QCancer (Renal) prediction model Cancer Epidemiology, February 25, 2013 Clinical Article

678 Prognostic value of bcl-2 expression among women with breast cancer in Libya Tumor Biology, February 25, 2013 Clinical Article

679 New developments in biomarkers for melanoma Current Opinion in Oncology, February 25, 2013 Clinical Article

680 Detection of Impaired Homologous Recombination Repair in NSCLC Cells and Tissues Journal of Thoracic Oncology, February 25, 2013 Clinical Article

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Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

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Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Oncology - Diagnostics/Radiology News & Articles

Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology