Oncology - Diagnostics/Radiology News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (4) Full Text Articles (304) Focus on Bone

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

461 Clinicopathological correlation for the role of fluorodeoxyglucose positron emission tomography computed tomography in detection of choroidal malignant melanoma International Journal of Clinical Oncology, March 8, 2013 Clinical Article

462 The role of 1.5 Tesla magnetic resonance imaging in staging prostate cancer ANZ Journal of Surgery, March 8, 2013 Review Article

463 The application of liquid-based cytology test of bronchial lavage fluid in lung cancer diagnosis Thoracic Cancer, March 8, 2013 Clinical Article

464 The role of intraoperative magnetic resonance imaging in complex meningioma surgery Magnetic Resonance Imaging, March 8, 2013 Clinical Article

465 Childhood cancer and factors related to prolonged diagnostic intervals: a Danish population-based study British Journal of Cancer, March 7, 2013 Review Article

466 Biopsy validation of 18F-DOPA PET and biodistribution in gliomas for neurosurgical planning and radiotherapy target delineation: results of a prospective pilot study Neuro-Oncology, March 7, 2013 Clinical Article

467 Surveillance MR Imaging is Superior to Serum Tumor Markers for Detecting Early Tumor Recurrence in Patients with Appendiceal Cancer Treated with Surgical Cytoreduction and HIPEC Annals of Surgical Oncology, March 7, 2013 Clinical Article

468 Distinguishing hairy cell leukemia variant from hairy cell leukemia: Development and validation of diagnostic criteria Leukemia Research, March 7, 2013 Clinical Article

469 CADM1 and MAL promoter methylation levels in hrHPV-positive cervical scrapes increase proportional to degree and duration of underlying cervical disease International Journal of Cancer, March 7, 2013 Clinical Article

470 Validation of the 7th Edition American Joint Committee on Cancer staging system for Esophageal Squamous Cell Carcinoma Thoracic Cancer, March 7, 2013 Review Article

471 18F-FDG PET/CT-based treatment response evaluation in locally advanced rectal cancer: a prospective validation of long-term outcomes European Journal of Nuclear Medicine & Molecular Imaging, March 7, 2013 Clinical Article

472 Identification of the variables associated with pain during transrectal ultrasonography-guided prostate biopsy in the era of periprostatic nerve block: the role of transrectal probe configuration BJU International, March 7, 2013 Clinical Article

473 Ciprofloxacin resistance in the faecal carriage of patients undergoing transrectal ultrasound guided prostate biopsy BJU International, March 7, 2013 Clinical Article

474 Multiparametric magnetic resonance imaging findings in men with low-risk prostate cancer followed using active surveillance BJU International, March 7, 2013 Clinical Article

475 Gastric adenocarcinoma has a unique microRNA signature not present in esophageal adenocarcinoma Cancer, March 6, 2013 Clinical Article

476 hnRNP K suppresses apoptosis independent of p53 status by maintaining high levels of endogenous caspase inhibitors Carcinogenesis, March 6, 2013 Clinical Article

477 Lung Metastases Treated with Image-guided Stereotactic Body Radiation Therapy Clinical Oncology, March 6, 2013 Clinical Article

478 MELD-sodium score and its prognostic value in malignancy-related ascites of pancreatic and gastric cancer Supportive Care in Cancer, March 6, 2013 Clinical Article

479 Factors related to biopsy willingness in patients with advanced cancer in a phase 1 clinic for molecularly targeted therapy Journal of Cancer Research & Clinical Oncology, March 6, 2013 Review Article

480 Tryptophan PET in pretreatment delineation of newly-diagnosed gliomas: MRI and histopathologic correlates Journal of Neuro-Oncology, March 6, 2013 Clinical Article

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Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 Quantitative Ultrasound Evaluation of Tumor Cell Death Response in Locally Advanced Breast Cancer Patients Receiving Chemotherapy Clinical Cancer Research, April 5, 2013

2 Pleural cancer antigen-125 levels in benign and malignant pleural effusions The International Journal of Tuberculosis and Lung Disease, April 10, 2013

3 Serum carbohydrate antigen 125 is not an independent prognostic factor in patients with chronic lymphocytic leukemia Cancer Biomarkers, April 11, 2013

4 A feasibility study of NIR fluorescent image-guided surgery in head and neck cancer based on the assessment of optimum surgical time as revealed through dynamic imaging OncoTargets and Therapy, April 11, 2013 Free full text

5 Expression of proliferation markers and cell cycle regulators in T cell lymphoproliferative skin disorders Journal of Dermatological Science, April 8, 2013

6 IL-6 expression predicts treatment response and outcome in squamous cell carcinoma of the esophagus Molecular Cancer, April 10, 2013 Free full text

7 Magnetic resonance imaging for prostate cancer clinical application Chinese Journal of Cancer Research, April 22, 2013 Free full text

8 18F-FDG PET SUVmax as an indicator of histopathologic response after neoadjuvant chemotherapy in extremity osteosarcoma European Journal of Nuclear Medicine & Molecular Imaging, April 11, 2013

9 The role of dynamic infrared imaging in melanoma diagnosis Expert Review of Dermatology, April 11, 2013

10 Pilot Study on the Feasibility of PET/CT Lymphoscintigraphy with 89Zr-Nanocolloidal Albumin for Sentinel Node Identification in Oral Cancer Patients The Journal of Nuclear Medicine, April 9, 2013
Exclusive Author Commentary

11 Clinical utility of measuring expression levels of KAP1, TIMP1 and STC2 in peripheral blood of patients with gastric cancer World Journal of Surgical Oncology, April 5, 2013 Free full text

12 Increased EHD1 in Non-small Cell Lung Cancer Predicts Poor Survival Thoracic Cancer, April 5, 2013

13 Anatomic MR Imaging and Functional Diffusion Tensor Imaging of Peripheral Nerve Tumors and Tumorlike Conditions American Journal of Neuroradiology, April 25, 2013

14 Plasma osteopontin velocity differentiates lung cancers from controls in a CT screening population Cancer Biomarkers, April 12, 2013

15 Diagnostic accuracy of 18F-FDG PET/CT for detecting recurrence in patients with primary skeletal Ewing sarcoma European Journal of Nuclear Medicine & Molecular Imaging, April 9, 2013

16 Total body computed tomography scan in the initial work-up of binet stage a chronic lymphocytic leukemia patients: Results of the prospective, multicenter o-cll1-gisl study American Journal of Hematology, April 9, 2013

17 Perfusion CT allows prediction of therapy response in non-small cell lung cancer treated with conventional and anti-angiogenic chemotherapy European Radiology, April 9, 2013

18 Increased Alpha-Fetoprotein Serum Level is Predictive for Survival and Recurrence of Hepatocellular Carcinoma in Non-Cirrhotic Livers Digestive Surgery, April 9, 2013 Free full text

19 Tumor-associated macrophages as a prognostic parameter in multiple myeloma Annals of Hematology, April 10, 2013

20 Gender differences in prognosis after esophagectomy for esophageal cancer Surgery Today, April 10, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more

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Oncology - Diagnostics/Radiology News & Articles

Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology