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Oncology - General Medical News & Articles
Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
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Articles
Latest (15) Full Text Articles (75) Focus on Leukemia/lymphoma981 Scientists find more precise way to turn off genes, a major goal of treatments that target cancer Full Text ScienceDaily, March 11, 2013
982 Why a hereditary anemia is caused by genetic mutation in mechanically sensitive ion channel Full Text ScienceDaily, March 11, 2013
983 BRAF Inhibitor Treatment Causes Melanoma Cells to Shift How They Produce Energy Full Text ScienceDaily, March 11, 2013
984 New drug shows promise in fighting inflammatory breast cancer Full Text ScienceDaily, March 11, 2013
985 Emotion-health connection not limited to industrialized nations Full Text ScienceDaily, March 11, 2013
986 States Seek to Direct Medicaid Patients to Exchanges Bloomberg News, March 11, 2013
987 HHS makes plans to speed data exchange Full Text Healthcare IT News, March 8, 2013
988 'Prevent death' message more effective than 'save life' in blood donation campaigns Full Text EurekAlert!, March 8, 2013
989 Involving other providers in palliative care may help meet growing demand Full Text EurekAlert!, March 8, 2013
990 A cancer-promoting protein is found to also suppress cell growth Full Text EurekAlert!, March 8, 2013
991 Penn Medicine physician: Emphasis on 'value' in health care reform sends mixed messages Full Text EurekAlert!, March 8, 2013
992 Processed meat linked to premature death Full Text EurekAlert!, March 8, 2013
993 Short bouts of exercise boost self control. Increased blood and oxygen flow to pre-frontal area of brain may explain effects Full Text EurekAlert!, March 8, 2013
994 New opportunities for 3-D technology in medicine Full Text ScienceDaily, March 8, 2013
995 Hope for stopping melanoma from spreading Full Text ScienceDaily, March 8, 2013
996 Scientists make mouse model of human cancer, demonstrate cure Full Text ScienceDaily, March 8, 2013
997 Improved ultrasound imaging coming soon Full Text ScienceDaily, March 8, 2013
998 Newly Identified Biomarkers May Help Predict Progression of Barrett's Esophagus to Esophageal Adenocarcinoma Full Text ScienceDaily, March 8, 2013
999 Visceral fat causally linked to intestinal cancer Full Text ScienceDaily, March 8, 2013
1000 Novel small molecules used to visualize prostate cancer Full Text ScienceDaily, March 8, 2013
Clinical Pearls in Oncology
- The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
- A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
- In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease
Highlights in Oncology
VEGFR-1 is a prognostic marker for HCC
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryHCC risk increased in patients with AIDS
As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryRAB25 is a prognostic marker for ovarian cancer
As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summaryMost Popular Oncology Articles
Last month's top read Top Articles of 20121 Johns Hopkins rewrites obsolete blood-ordering rules EurekAlert!, May 24, 2013 Free full text
2 Diet Changes That Might Cut Breast Cancer Risk U.S. News & World Report - Health, May 17, 2013
3 The compound in the Mediterranean diet that makes cancer cells 'mortal' EurekAlert!, May 21, 2013 Free full text
4 Harvard deploys big data for bio study Healthcare IT News, May 6, 2013 Free full text
5 Mechanism linking key inflammatory marker to cancer identified ScienceDaily, May 22, 2013 Free full text
6 What to Know Before You Glow U.S. News & World Report - Health, May 30, 2013
7 EMR and HIE see big adoption numbers Healthcare IT News, May 13, 2013 Free full text
8 Mostashari urges healthcare change Healthcare IT News, May 16, 2013 Free full text
9 ONC launches apps challenge Healthcare IT News, May 21, 2013 Free full text
10 Peregrine Pharma agrees with FDA on lung cancer trial design Reuters Health News, May 22, 2013 Free full text
11 New pathway, enhancing tamoxifen to tame aggressive breast cancer identified ScienceDaily, April 24, 2013 Free full text
12 Religious support tied to intensive end-of-life care Reuters Health News, May 9, 2013 Free full text
13 Amplification of a Stat5 gene produces excess oncogenic protein that drives prostate cancer spread EurekAlert!, May 9, 2013 Free full text
14 Computational tool translates complex data into simplified 2-dimensional images EurekAlert!, May 21, 2013 Free full text
15 Small molecule could have big impact on cancer EurekAlert!, May 29, 2013 Free full text
16 Mayo Clinic: How gold nanoparticles can help fight ovarian cancer EurekAlert!, May 22, 2013 Free full text
17 Soy and tomato combo may be effective in preventing prostate cancer EurekAlert!, May 9, 2013 Free full text
18 Slowing health-care costs may be here to stay The Seattle Times, May 9, 2013 Free full text
19 Researchers discover master regulator that drives majority of lymphoma EurekAlert!, May 14, 2013 Free full text
20 Penn Medicine researchers identify 4 new genetic risk factors for testicular cancer EurekAlert!, May 13, 2013 Free full text
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
Other Topics in Oncology
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