Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Oncology
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D Scott Cunningham MD, PhD
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1 Anti-tumor effects of various furocoumarins isolated from the roots, seeds and fruits of Angelica and Cnidium species under ultraviolet A irradiation Journal of Natural Medicines, May 22, 2013 Clinical Article
2 Folic acid prevents the initial occurrence of sporadic colorectal adenoma in Chinese over 50 years of age: a randomized clinical trial Cancer Prevention Research, May 20, 2013 Clinical Article
3 Sensitivity of assays for the detection of HPA-1a antibodies: results of an international workshop demonstrating the impact of cation chelation from integrin αIIbβ3 on three widely used assays Vox Sanguinis, May 14, 2013 Clinical Article
4 Caffeic acid-conjugated chitosan derivatives and their anti-tumor activity Full Text Archives of Pharmacal Research, May 13, 2013 Review Article
5 The immunomodulatory and anticancer properties of propolis Clinical Reviews in Allergy and Immunology, May 9, 2013 Review Article
6 Impact of Standardized Allergen-Removed Rhus verniciflua Stokes Extract on Advanced Adenocarcinoma of the Ampulla of Vater: A Case Series Full Text Evidence-based Complementary and Alternative Medicine , May 8, 2013 Clinical Article
7 Characterization of a novel curcumin analog P1 as potent inhibitor of the NF-kB signaling pathway with distinct mechanisms Acta Pharmacologica Sinica, May 7, 2013 Clinical Article
8 Ethnopharmacological and bioactivity guided investigation of five TCM anticancer herbs Journal of Ethnopharmacology , May 6, 2013 Review Article
9 Advanced Targeted, Cell and Gene-Therapy Approaches for Pediatric Hematological Malignancies: Results and Future Perspectives Frontiers in Oncology, May 3, 2013 Clinical Article
10 Monoclonal antibody against the ectodomain of E-cadherin (DECMA-1) suppresses breast carcinogenesis: Involvement of the HER/PI3K/Akt/mTOR and IAP pathways Clinical Cancer Research, April 30, 2013 Clinical Article
11 Antihyperglycemic Drug Gymnema sylvestre Also Shows Anticancer Potentials in Human Melanoma A375 Cells via Reactive Oxygen Species Generation and Mitochondria-Dependent Caspase Pathway Integrative Cancer Therapies , April 30, 2013 Clinical Article
12 Personalized peptide vaccination: a new approach for advanced cancer as therapeutic cancer vaccine Cancer Immunology, Immunotherapy, April 29, 2013 Review Article
13 CD39 is highly involved in mediating the suppression activity of tumor-infiltrating CD8+ T regulatory lymphocytes Cancer Immunology, Immunotherapy, April 29, 2013 Clinical Article
14 Extracts from Epilobium sp. herbs induce apoptosis in human hormone-dependent prostate cancer cells by activating the mitochondrial pathway Journal of Pharmacy and Pharmacology, April 29, 2013 Clinical Article
15 Phyllanthus Suppresses Prostate Cancer Cell, PC-3, Proliferation and Induces Apoptosis through Multiple Signalling Pathways (MAPKs, PI3K/Akt, NFB, and Hypoxia) Full Text Evidence-based Complementary and Alternative Medicine , April 26, 2013 Clinical Article
16 Efficient ex vivo induction of T cells with potent anti-tumor activity by protein antigen encapsulated in nanoparticles Cancer Immunology, Immunotherapy, April 26, 2013 Clinical Article
17 Intratumoral injection of therapeutic HPV vaccinia vaccine following cisplatin enhances HPV-specific antitumor effects Cancer Immunology, Immunotherapy, April 26, 2013 Clinical Article
18 Immunomodulatory effects of the botanical compound LCS101: implications for cancer treatment Full Text OncoTargets and Therapy, April 26, 2013 Clinical Article
19 Antibody-peptide-MHC fusion conjugates target non-cognate T cells to kill tumour cells Cancer Immunology, Immunotherapy, April 25, 2013 Clinical Article
20 Decursin Exerts Anti-cancer Activity in MDA-MB-231 Breast Cancer Cells Via Inhibition of the Pin1 Activity and Enhancement of the Pin1/p53 Association Phytotherapy Research, April 22, 2013 Clinical Article
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summaryIndexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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