Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Oncology
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D Scott Cunningham MD, PhD
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21 2-Hydroxy-3-methylanthraquinone from Hedyotis diffusa Willd induces apoptosis in human leukemic U937 cells through modulation of MAPK pathways Full Text Archives of Pharmacal Research, April 17, 2013 Review Article
22 Quality of reporting and its correlates among randomized controlled trials on acupuncture for cancer pain Expert Review of Anticancer Therapy, April 16, 2013 Clinical Article
23 Impact of Phytolacca americana Extracts on Gene Expression of Colon Cancer Cells Phytotherapy Research, April 15, 2013 Review Article
24 Bortezomib, dexamethasone plus thalidomide for treatment of newly diagnosed multiple myeloma patients with or without renal impairment Full Text Chinese Journal of Cancer Research, April 12, 2013 Clinical Article
25 Combining cancer immunotherapy and targeted therapy Current Opinion in Immunology, April 8, 2013 Clinical Article
26 Hemidesmus indicus induces apoptosis as well as differentiation in a human promyelocytic leukemic cell line Journal of Ethnopharmacology , April 8, 2013 Review Article
27 Effect of a Congolese herbal medicine used in sickle cell anemia on the expression of plasminogen activators in human coronary aortic endothelial cells culture Journal of Ethnopharmacology , April 5, 2013 Clinical Article
28 Dammarane-type saponins from heat-processed Gynostemma pentaphyllum show fortified activity against A549 cells Full Text Archives of Pharmacal Research, April 5, 2013 Review Article
29 Chemopreventive and Therapeutic Potential of Tea Polyphenols in Hepatocellular Cancer Nutrition and Cancer, April 4, 2013 Review Article
30 Cost analysis of adjuvant therapy with XELOX or FOLFOX4 for colon cancer Colorectal Disease, April 3, 2013 Clinical Article
31 Home-based zoledronic acid infusion therapy in patients with solid tumours: compliance and patient-nurse satisfaction Bulletin du Cancer, April 3, 2013 Clinical Article
32 Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway Carcinogenesis, April 1, 2013 Clinical Article
33 Thermal ablation in the treatment of lung cancer: present and future European Journal of Cardio-Thoracic Surgery, April 1, 2013 Clinical Article
34 Induction of Cell Cycle Arrest and Apoptosis in Human Osteosarcoma U-2 OS Cells by Solanum lyratum Extracts Nutrition and Cancer, March 29, 2013 Clinical Article
35 The Histone Demethylase PHF8 Governs Retinoic Acid Response in Acute Promyelocytic Leukemia Cancer Cell, March 27, 2013 Clinical Article
36 Cucurbitacin I Inhibits Rac1 Activation in Breast Cancer Cells by a Ros-Mediated Mechanism and Independently of Jak2 and P-Rex1 Molecular Pharmacology, March 22, 2013 Review Article
37 Oleanane-type triterpenoid saponins from the roots of Pulsatilla koreana and their apoptosis-inducing effects on HL-60 human promyelocytic leukemia cells Full Text Archives of Pharmacal Research, March 21, 2013 Review Article
38 TLR agonists: our best frenemy in cancer immunotherapy Journal of Leukocyte Biology, March 18, 2013 Review Article
39 Fuyuan Decoction inhibits nitric oxide production via inactivation of nuclear factor-kB in SW1353 chondrosarcoma cells Journal of Ethnopharmacology , March 15, 2013 Review Article
40 New Strategies in Hodgkin Lymphoma: Better Risk Profiling and Novel Treatments Clinical Cancer Research, March 13, 2013 Clinical Article
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 Efficient ex vivo induction of T cells with potent anti-tumor activity by protein antigen encapsulated in nanoparticles Cancer Immunology, Immunotherapy, April 26, 2013
2 Phyllanthus Suppresses Prostate Cancer Cell, PC-3, Proliferation and Induces Apoptosis through Multiple Signalling Pathways (MAPKs, PI3K/Akt, NFB, and Hypoxia) Evidence-based Complementary and Alternative Medicine , April 26, 2013 Free full text
3 Thermal ablation in the treatment of lung cancer: present and future European Journal of Cardio-Thoracic Surgery, April 1, 2013
4 Immunomodulatory effects of the botanical compound LCS101: implications for cancer treatment OncoTargets and Therapy, April 26, 2013 Free full text
5 Intratumoral injection of therapeutic HPV vaccinia vaccine following cisplatin enhances HPV-specific antitumor effects Cancer Immunology, Immunotherapy, April 26, 2013
6 Combining cancer immunotherapy and targeted therapy Current Opinion in Immunology, April 8, 2013
7 Fuyuan Decoction inhibits nitric oxide production via inactivation of nuclear factor-kB in SW1353 chondrosarcoma cells Journal of Ethnopharmacology , March 15, 2013 Review Article
8 Quality of reporting and its correlates among randomized controlled trials on acupuncture for cancer pain Expert Review of Anticancer Therapy, April 16, 2013
9 Chemopreventive and Therapeutic Potential of Tea Polyphenols in Hepatocellular Cancer Nutrition and Cancer, April 4, 2013 Review Article
10 Impact of Phytolacca americana Extracts on Gene Expression of Colon Cancer Cells Phytotherapy Research, April 15, 2013 Review Article
11 2-Hydroxy-3-methylanthraquinone from Hedyotis diffusa Willd induces apoptosis in human leukemic U937 cells through modulation of MAPK pathways Archives of Pharmacal Research, April 17, 2013 Free full text Review Article
12 Hemidesmus indicus induces apoptosis as well as differentiation in a human promyelocytic leukemic cell line Journal of Ethnopharmacology , April 8, 2013 Review Article
13 Reading the Tea Leaves of Tumor-Mediated Immunosuppression Clinical Cancer Research, February 27, 2013
14 TLR agonists: our best frenemy in cancer immunotherapy Journal of Leukocyte Biology, March 18, 2013 Review Article
15 Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway Carcinogenesis, April 1, 2013
16 Changes of immunological parameters with administration of Japanese Kampo medicine (Juzen-Taihoto/TJ-48) in patients with advanced pancreatic cancer International Journal of Clinical Oncology, March 1, 2013
17 The Histone Demethylase PHF8 Governs Retinoic Acid Response in Acute Promyelocytic Leukemia Cancer Cell, March 27, 2013
18 New Strategies in Hodgkin Lymphoma: Better Risk Profiling and Novel Treatments Clinical Cancer Research, March 13, 2013
19 Cost analysis of adjuvant therapy with XELOX or FOLFOX4 for colon cancer Colorectal Disease, April 3, 2013
20 Antibody-peptide-MHC fusion conjugates target non-cognate T cells to kill tumour cells Cancer Immunology, Immunotherapy, April 25, 2013
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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