Dermatologic Oncology News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (2) Full Text Articles (147) Focus on Bone

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

481 Epidermal Growth Factor Facilitates Melanoma Lymph Node Metastasis by Influencing Tumor Lymphangiogenesis Journal of Investigative Dermatology, September 7, 2012

482 Raising the bar for melanoma cancer gene discovery Pigment Cell & Melanoma Research, September 6, 2012

483 Vitamin D and Melanoma Incidence and Mortality Pigment Cell & Melanoma Research, September 6, 2012

484 Sentinel lymph node metastasis is not predictive of poor outcome in patients with problematic spitzoid melanocytic tumors Human Pathology, September 5, 2012

485 Well MET: Exosomes promote metastasis through transfer of MET from melanoma to bone marrow progenitors Pigment Cell & Melanoma Research, September 4, 2012

486 LKB1 suppresses melanoma metastasis: The answer is YES Pigment Cell & Melanoma Research, September 4, 2012

487 Halofugine prevents cutaneous graft versus host disease by suppression of Th17 differentiation Hematology, September 4, 2012

488 Fishing for melanoma markers through comparative transcriptome analysis Pigment Cell & Melanoma Research, September 4, 2012

489 p53R2 is a prognostic factor of melanoma and regulates proliferation and chemosensitivity of melanoma cells Journal of Dermatological Science, September 4, 2012 Clinical Article

490 Dermoscopic diagnosis of melanoma in a 4D space constructed by active contour extracted features Computerized Medical Imaging and Graphics , September 4, 2012

491 Melanoma ex blue nevus: two cases resembling large plaque-type blue nevus with subcutaneous cellular nodules Journal of Cutaneous Pathology, August 31, 2012

492 Expression of p16 alone does not differentiate between Spitz nevi and spitzoid melanoma Journal of Cutaneous Pathology, August 31, 2012

493 A concise review of the efficacy of stereotactic radiosurgery in the management of melanoma and renal cell carcinoma brain metastases World Journal of Surgical Oncology, August 31, 2012 Clinical Article

494 BRAF Mutation, NRAS Mutation, and the Absence of an Immune-Related Expressed Gene Profile Predict Poor Outcome in Patients with Stage III Melanoma Journal of Investigative Dermatology, August 31, 2012

495 Cutaneous Squamous Cell Carcinoma and Human Papillomavirus: Is There an Association Dermatologic Surgery, August 30, 2012 Clinical Article

496 Oncogenic BRAF(V600E) Promotes Stromal Cell-Mediated Immunosuppression Via Induction of Interleukin-1 in Melanoma Clinical Cancer Research, August 30, 2012

497 The clinical profile of Merkel cell carcinoma in mainland China International Journal of Dermatology, August 30, 2012

498 Protein kinase A activation inhibits oncogenic Sonic hedgehog signaling and suppresses basal cell carcinoma of the skin Experimental Dermatology, August 30, 2012

499 Outcomes and prognostic factors in nodular melanomas Surgery, August 30, 2012 Clinical Article

500 Basal cell carcinoma on the dorsum of the foot with inguinal and pelvic lymph nodes metastases International Journal of Dermatology, August 29, 2012

50 available pages First Previous 25 26 27 28 29 30 31 32 33 34 Next Last

Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 Completion lymph node dissection after a positive sentinel node: no longer a must Current Opinion in Oncology, March 4, 2013 Review Article

2 Rare BRAF mutations in melanoma patients: implications for molecular testing in clinical practice British Journal of Cancer, April 12, 2013 Review Article

3 P21-activated kinase 1 (pak1) as a therapeutic target in braf wild-type melanoma Journal of the National Cancer Institute, April 1, 2013

4 Mohs Versus Surgical Excision in Nonmelanoma Skin Cancers: Does Location Matter? Annals of Plastic Surgery, April 11, 2013 Review Article

5 Clinicopathologic Features of Primary Merkel Cell Carcinoma: A Detailed Descriptive Analysis of a Large Contemporary Cohort Dermatologic Surgery, April 8, 2013

6 Long-term survival and immunological parameters in metastatic melanoma patients who responded to ipilimumab 10mg/kg within an expanded access programme Cancer Immunology, Immunotherapy, April 23, 2013

7 Phase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma Journal of Clinical Oncology, January 10, 2013

8 Efficacy and safety of retreatment with ipilimumab in patients with pretreated advanced melanoma who progressed after initially achieving disease control Clinical Cancer Research, April 9, 2013

9 Predicting Disease Progression After Regional Therapy for In-Transit Melanoma Disease Progression After Regional Therapy JAMA Surgery, April 9, 2013 Review Article

10 MERTK receptor tyrosine kinase is a therapeutic target in melanoma The Journal of Clinical Investigation, April 25, 2013 Free full text

11 Efficacy and safety of retreatment with ipilimumab in patients with pretreated advanced melanoma who progressed after initially achieving disease control Clinical Cancer Research, March 4, 2013

12 Advanced basal cell carcinoma of the skin: targeting the hedgehog pathway Current Opinion in Oncology, April 24, 2013 Review Article

13 Clinical activity and safety of combination therapy with temsirolimus and bevacizumab for advanced melanoma: A Phase II trial (CTEP 7190/ Mel47) Clinical Cancer Research, April 29, 2013

14 Occupational exposure to arsenic and risk of non-melanoma skin cancer in a multinational European study International Journal of Cancer, April 25, 2013

15 Establishment of a novel experimental model of human angiosarcoma and a VEGF-targeting therapeutic experiment Journal of Dermatological Science, April 1, 2013

16 Increasing the therapeutic efficacy of docetaxel for cutaneous squamous cell carcinoma through the combined inhibition of phosphatidylinositol 3-kinase/AKT signalling and autophagy Clinical and Experimental Dermatology, March 28, 2013

17 Lymph/angiogenesis gene variants and melanoma progression Cancer Epidemiology, Biomarkers & Prevention, April 17, 2013

18 Superficial and deep lymph node dissection for stage III cutaneous melanoma: clinical outcome and prognostic factors World Journal of Surgical Oncology, February 12, 2013

19 Effects of BRAF inhibitors on Human Melanoma Tissue Before Treatment, Early During Treatment and on Progression Pigment Cell & Melanoma Research, April 10, 2013

20 Amiodarone and the risk of cancer Cancer, April 9, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more

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Dermatologic Oncology News & Articles

Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology