Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Oncology
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D Scott Cunningham MD, PhD
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1 Treatment of local-regional prostate cancer detected by PSA screening: benefits and harms according to prognostic factors British Journal of Cancer, May 17, 2013
2 Prognostic significance of Bcl-xL expression and efficacy of Bcl-xL targeting therapy in urothelial carcinoma British Journal of Cancer, May 17, 2013
3 Coffee consumption and the risk of prostate cancer: the Ohsaki Cohort Study British Journal of Cancer, May 17, 2013
4 Egg consumption and risk of bladder cancer: a meta-analysis Nutrition and Cancer, May 17, 2013 Clinical Article
5 Agent Orange as a risk factor for high-grade prostate cancer Cancer, May 17, 2013 Clinical Article
6 A dose-ranging study of cabozantinib in men with castration-resistant prostate cancer and bone metastases Clinical Cancer Research, May 17, 2013 Clinical Article
7 Intravesical bacille calmette-guerin eradicates bacteriuria in antibiotic-naive bladder cancer patients Full Text European Urology, May 17, 2013 Clinical Article
8 Reflex immunocyt testing for the diagnosis of bladder cancer in patients with atypical urine cytology Full Text European Urology, May 17, 2013 Clinical Article
9 CCN3 promotes prostate cancer bone metastasis by modulating the tumor–bone microenvironment through RANKL-dependent pathway Carcinogenesis, May 17, 2013 Clinical Article
10 Hypoxic Tumor Kinase Signaling Mediated by STAT5A in Development of Castration-Resistant Prostate Cancer PLOS ONE, May 17, 2013 Clinical Article
11 Clinical implementation of quality of life instruments and prediction tools for localized prostate cancer: results from a national survey of radiation oncologists and urologists The Journal of Urology, May 16, 2013 Clinical Article
12 Effects of serenoa repens, selenium and lycopene (profluss®) on chronic inflammation associated with benign prostatic hyperplasia: results of "flog" (flogosis and profluss in prostatic and genital disease), a multicentre italian study Full Text International Braz J Urol, May 16, 2013 Clinical Article
13 Image guided hypofractionated radiotherapy and quality of life for localized prostate cancer: prospective longitudinal study in 337 patients The Journal of Urology, May 16, 2013 Clinical Article
14 Overall survival advantage with partial nephrectomy: A bias of observational data? Cancer, May 16, 2013 Clinical Article
15 Perspectives on treatment of metastatic castration-resistant prostate cancer Full Text The Oncologist, May 16, 2013 Review Article
16 CRM1 Blockade by Selective Inhibitors of Nuclear Export Attenuates Kidney Cancer Growth The Journal of Urology, May 16, 2013 Clinical Article
17 Nuclear expression of Smad proteins and its prognostic significance in clear cell renal cell carcinoma Human Pathology, May 16, 2013 Clinical Article
18 Toll-like receptor-associated sequence variants and prostate cancer risk among men of African descent Genes and Immunity, May 16, 2013 Clinical Article
19 The association between overall survival of prostate cancer patients and hypertension, hyperglycemia, and overweight in Southern China: a prospective cohort study Journal of Cancer Research & Clinical Oncology, May 15, 2013 Clinical Article
20 High Circulating Estrogens and Selective Expression of ER{beta} in Prostate Tumors: Implications for Racial Disparity of Prostate Cancer Carcinogenesis, May 15, 2013 Clinical Article
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 Clinical activity of abiraterone acetate in patients with metastatic castration-resistant prostate cancer progressing after enzalutamide Annals of Oncology, April 19, 2013
2 Antitumour activity of abiraterone acetate against metastatic castration-resistant prostate cancer progressing after docetaxel and enzalutamide (MDV3100) Annals of Oncology, April 16, 2013
3 Gene-Environment Interactions in Bladder Cancer Cancer Research, April 1, 2013
4 Abiraterone and Novel Antiandrogens: Overcoming Castration Resistance in Prostate Cancer Annual Review of Medicine, April 26, 2013 Review Article
5 Ipilimumab alone or in combination with radiotherapy in metastatic castration-resistant prostate cancer: results from an open-label, multicenter phase I/II study Annals of Oncology, April 3, 2013
6 The role of surgery for metastatic renal cell carcinoma in the era of targeted therapies World Journal of Urology, April 2, 2013 Review Article
7 Emerging therapies in metastatic castration-sensitive and castration-resistant prostate cancer Current Opinion in Oncology, April 10, 2013 Review Article
8 Up-regulation of TGM2 with ITGB1 and SDC4 is important in the development and metastasis of renal cell carcinoma Urologic Oncology: Seminars and Original Investigations, April 1, 2013
9 Axitinib versus sorafenib as second-line treatment for advanced renal cell carcinoma: overall survival analysis and updated results from a randomised phase 3 trial The Lancet Oncology, April 24, 2013
10 Advances in bladder cancer imaging BMC Medicine, April 15, 2013 Free full text Review Article
11 Androgen deprivation therapy and the risk of colorectal cancer in patients with prostate cancer Cancer Causes and Control, April 8, 2013
12 Clinical outcomes in patients receiving three lines of targeted therapy for metastatic renal cell carcinoma: Results from a large patient cohort European Journal of Cancer, March 22, 2013
13 Predicted plasma 25-hydroxyvitamin D and risk of renal cell cancer Journal of the National Cancer Institute, April 11, 2013
14 Long-term safety and efficacy of sustained eculizumab treatment in patients with paroxysmal nocturnal haemoglobinuria British Journal of Haematology, April 26, 2013
15 Low serum testosterone levels are predictive of prostate cancer World Journal of Urology, April 9, 2013
16 Aberrant BAF57 Signaling Facilitates Pro-metastatic Phenotypes Clinical Cancer Research, April 1, 2013
17 Clinical judgment versus biomarker prostate cancer gene 3: which is best when determining the need for repeat prostate biopsy? Urology, March 25, 2013
18 Cardiovascular outcomes in patients with locally advanced and metastatic prostate cancer treated with luteinising-hormone-releasing-hormone agonists or transdermal oestrogen: the randomised, phase 2 MRC PATCH trial (PR09) The Lancet Oncology, March 7, 2013
19 Urothelial carcinoma of the bladder and the upper tract: disparate twins The Journal of Urology, April 18, 2013 Review Article
20 A prospective evaluation of VEGF-targeted treatment cessation in metastatic clear cell renal cancer Annals of Oncology, April 19, 2013
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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