Oncology - Renal/Urologic News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (10) Full Text Articles (529) Focus on Pancreas

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

981 Percutaneous Ablation of Renal Masses Measuring 3.0 cm and Smaller: Comparative Local Control and Complications After Radiofrequency Ablation and Cryoablation American Journal of Roentgenology, January 29, 2013 Review Article

982 Hepatitis A virus cellular receptor 1/kidney injury molecule-1 is a susceptibility gene for clear cell renal cell carcinoma and hepatitis A virus cellular receptor/kidney injury molecule-1 ectodomain shedding a predictive biomarker of tumour progression European Journal of Cancer, January 29, 2013 Clinical Article

983 Silencing of mutant p53 by siRNA induces cell cycle arrest and apoptosis in human bladder cancer cells World Journal of Surgical Oncology, January 29, 2013 Review Article

984 Castration therapy results in decreased Ku70 levels in prostate cancer Clinical Cancer Research, January 28, 2013 Clinical Article

985 Loss of SPARC in bladder cancer enhances carcinogenesis and progression Full Text The Journal of Clinical Investigation, January 28, 2013 Clinical Article

986 Targeting Constitutively Activated β1 Integrin inhibits Prostate Cancer Metastasis Molecular Cancer Research, January 28, 2013 Clinical Article

987 Radiosensitization in prostate cancer: mechanisms and targets BMC Urology, January 28, 2013 Review Article

988 Risk of localized and advanced prostate cancer among immigrants versus native-born Swedish men: a nation-wide population-based study Cancer Causes and Control, January 28, 2013 Review Article

989 Do differences in clinical symptoms and referral patterns contribute to the gender gap in bladder cancer BJU International, January 28, 2013 Review Article

990 Renal Epithelioid Angiomyolipoma: Imaging Characteristics in Nine Cases With Radiologic-Pathologic Correlation and Review of the Literature American Journal of Roentgenology, January 28, 2013 Review Article

991 Bladder cancer and seroreactivity to BK, JC and merkel cell polyomaviruses: The spanish bladder cancer study International Journal of Cancer, January 28, 2013 Clinical Article

992 Liposarcoma of the spermatic cord mimicking a left inguinal hernia: a case report and literature review World Journal of Surgical Oncology, January 28, 2013

993 A case of MPO- and PR3-ANCA-negative pauci-immune renal-limited small-vessel vasculitis associated with endometrial neuroendocrine small cell carcinoma Clinical and Experimental Nephrology Case Reports, January 28, 2013

994 Overall and cancer-specific survival of patients with breast, colon, kidney, and lung cancers with and without chronic lymphocytic leukemia: A SEER population-based study Journal of Clinical Oncology, January 25, 2013

995 Folic acid supplementation and cancer risk: A meta-analysis of randomized controlled trials International Journal of Cancer, January 25, 2013 Review Article

996 New Strategies in Prostate Cancer - Translating Genomics into the Clinic Clinical Cancer Research, January 25, 2013 Clinical Article

997 Validation of the prognostic grouping of the seventh edition of the tumor-nodes-metastasis classification using a large-scale prospective cohort study database of prostate cancer treated with primary androgen deprivation therapy International Journal of Urology, January 25, 2013 Clinical Article

998 Prostate cancer disease severity and country of origin among black men in the United States Prostate Cancer & Prostatic Diseases, January 24, 2013 Clinical Article

999 Prognostic value of ERG oncoprotein in prostate cancer recurrence and cause-specific mortality The Prostate, January 24, 2013 Clinical Article

1000 HIC1 modulates prostate cancer progression by epigentic modification Clinical Cancer Research, January 24, 2013 Clinical Article

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Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 Clinical activity of abiraterone acetate in patients with metastatic castration-resistant prostate cancer progressing after enzalutamide Annals of Oncology, April 19, 2013

2 Antitumour activity of abiraterone acetate against metastatic castration-resistant prostate cancer progressing after docetaxel and enzalutamide (MDV3100) Annals of Oncology, April 16, 2013

3 Gene-Environment Interactions in Bladder Cancer Cancer Research, April 1, 2013

4 Abiraterone and Novel Antiandrogens: Overcoming Castration Resistance in Prostate Cancer Annual Review of Medicine, April 26, 2013 Review Article

5 Ipilimumab alone or in combination with radiotherapy in metastatic castration-resistant prostate cancer: results from an open-label, multicenter phase I/II study Annals of Oncology, April 3, 2013

6 The role of surgery for metastatic renal cell carcinoma in the era of targeted therapies World Journal of Urology, April 2, 2013 Review Article

7 Emerging therapies in metastatic castration-sensitive and castration-resistant prostate cancer Current Opinion in Oncology, April 10, 2013 Review Article

8 Up-regulation of TGM2 with ITGB1 and SDC4 is important in the development and metastasis of renal cell carcinoma Urologic Oncology: Seminars and Original Investigations, April 1, 2013

9 Axitinib versus sorafenib as second-line treatment for advanced renal cell carcinoma: overall survival analysis and updated results from a randomised phase 3 trial The Lancet Oncology, April 24, 2013

10 Advances in bladder cancer imaging BMC Medicine, April 15, 2013 Free full text Review Article

11 Androgen deprivation therapy and the risk of colorectal cancer in patients with prostate cancer Cancer Causes and Control, April 8, 2013

12 Clinical outcomes in patients receiving three lines of targeted therapy for metastatic renal cell carcinoma: Results from a large patient cohort European Journal of Cancer, March 22, 2013

13 Predicted plasma 25-hydroxyvitamin D and risk of renal cell cancer Journal of the National Cancer Institute, April 11, 2013

14 Long-term safety and efficacy of sustained eculizumab treatment in patients with paroxysmal nocturnal haemoglobinuria British Journal of Haematology, April 26, 2013

15 Low serum testosterone levels are predictive of prostate cancer World Journal of Urology, April 9, 2013

16 Aberrant BAF57 Signaling Facilitates Pro-metastatic Phenotypes Clinical Cancer Research, April 1, 2013

17 Clinical judgment versus biomarker prostate cancer gene 3: which is best when determining the need for repeat prostate biopsy? Urology, March 25, 2013

18 Cardiovascular outcomes in patients with locally advanced and metastatic prostate cancer treated with luteinising-hormone-releasing-hormone agonists or transdermal oestrogen: the randomised, phase 2 MRC PATCH trial (PR09) The Lancet Oncology, March 7, 2013

19 Urothelial carcinoma of the bladder and the upper tract: disparate twins The Journal of Urology, April 18, 2013 Review Article

20 A prospective evaluation of VEGF-targeted treatment cessation in metastatic clear cell renal cancer Annals of Oncology, April 19, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more

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Oncology - Renal/Urologic News & Articles

Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology