Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Oncology
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D Scott Cunningham MD, PhD
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841 Estrogen receptor β (ERβ) is a novel prognostic marker of recurrence survival in non-muscle-invasive bladder cancer potentially by inhibiting cadherin switch World Journal of Urology, February 18, 2013 Clinical Article
842 Upper urinary tract instillations in the treatment of urothelial carcinomas: a review of technical constraints and outcomes World Journal of Urology, February 18, 2013 Review Article Clinical Article
843 Telomere crisis in kidney epithelial cells promotes the acquisition of a microRNA signature retrieved in aggressive renal cell carcinomas Carcinogenesis, February 18, 2013 Clinical Article
844 Transcription signatures encoded by ultraconserved genomic regions in human prostate cancer Full Text Molecular Cancer, February 18, 2013 Clinical Article
845 Urinary Tract Infection Increases the Subsequent Urinary Tract Cancer Risk: A Population-based Cohort Study Cancer Science, February 18, 2013 Review Article
846
Comprehensive overview of the efficacy and safety of sorafenib in advanced or metastatic renal cell carcinoma after a first tyrosine kinase inhibitor
Clinical and Translational Oncology, February 18, 2013
Clinical Article
Exclusive Author Commentary
847 Decreased expression of microRNA-31 associates with aggressive tumor progression and poor prognosis in patients with bladder cancer Clinical and Translational Oncology, February 18, 2013 Clinical Article
848 Androgenetic alopecia and risk of prostate cancer: A systematic review and meta-analysis Journal of the American Academy of Dermatology, February 15, 2013 Evidence Based Medicine Clinical Article
849
Anti-Oligomannose Antibodies as Potential Serum Biomarkers of Aggressive Prostate Cancer
Drug Development Research, February 15, 2013
Clinical Article
Exclusive Author Commentary
850 Incorporating endorectal MR elastography into multi-parametric MRI for prostate cancer imaging: Initial feasibility in volunteers Journal of Magnetic Resonance Imaging, February 15, 2013 Review Article
851 Bone Targeted Therapies in Metastatic Castration-Resistant Prostate Cancer Full Text The Cancer Journal, February 15, 2013 Clinical Article
852 From bevacizumab to tasquinimod: angiogenesis as a therapeutic target in prostate cancer Full Text The Cancer Journal, February 15, 2013 Clinical Article
853 Predicting progression of bladder urothelial carcinoma using microRNA expression BJU International, February 15, 2013 Clinical Article
854 Retroperitoneal teratoma with somatic malignant transformation: A papillary renal cell carcinoma in a testicular germ cell tumour metastasis following platinum-based chemotherapy Full Text BMC Urology, February 15, 2013
855 Association between metabolic syndrome, diabetes mellitus and prostate cancer risk Prostate Cancer & Prostatic Diseases, February 15, 2013 Clinical Article
856 Health disparities in clinical practice patterns for prostate cancer screening by geographic regions in the United States: a multilevel modeling analysis Prostate Cancer & Prostatic Diseases, February 15, 2013 Clinical Article
857 Diagnostic Performance of Contrast Enhanced Ultrasound in Patients with Prostate Cancer: A Meta-Analysis Academic Radiology, February 14, 2013 Evidence Based Medicine
858 A Prospective Longitudinal Survey of Erectile Dysfunction in Patients with Localized Prostate Cancer Treated with Permanent Prostate Brachytherapy The Journal of Urology, February 14, 2013 Clinical Guideline
859 The Number of Cores Taken in Patients Diagnosed with a Single Microfocus at Initial Biopsy is a Major Predictor of Insignificant Prostate Cancer The Journal of Urology, February 14, 2013 Clinical Guideline
860 The investigational Aurora kinase A inhibitor MLN8237 induces defects in cell viability and cell cycle progression in bladder cancer cells in vitro and in vivo Clinical Cancer Research, February 14, 2013 Clinical Article
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 Clinical activity of abiraterone acetate in patients with metastatic castration-resistant prostate cancer progressing after enzalutamide Annals of Oncology, April 19, 2013
2 Antitumour activity of abiraterone acetate against metastatic castration-resistant prostate cancer progressing after docetaxel and enzalutamide (MDV3100) Annals of Oncology, April 16, 2013
3 Gene-Environment Interactions in Bladder Cancer Cancer Research, April 1, 2013
4 Abiraterone and Novel Antiandrogens: Overcoming Castration Resistance in Prostate Cancer Annual Review of Medicine, April 26, 2013 Review Article
5 Ipilimumab alone or in combination with radiotherapy in metastatic castration-resistant prostate cancer: results from an open-label, multicenter phase I/II study Annals of Oncology, April 3, 2013
6 The role of surgery for metastatic renal cell carcinoma in the era of targeted therapies World Journal of Urology, April 2, 2013 Review Article
7 Emerging therapies in metastatic castration-sensitive and castration-resistant prostate cancer Current Opinion in Oncology, April 10, 2013 Review Article
8 Up-regulation of TGM2 with ITGB1 and SDC4 is important in the development and metastasis of renal cell carcinoma Urologic Oncology: Seminars and Original Investigations, April 1, 2013
9 Axitinib versus sorafenib as second-line treatment for advanced renal cell carcinoma: overall survival analysis and updated results from a randomised phase 3 trial The Lancet Oncology, April 24, 2013
10 Advances in bladder cancer imaging BMC Medicine, April 15, 2013 Free full text Review Article
11 Androgen deprivation therapy and the risk of colorectal cancer in patients with prostate cancer Cancer Causes and Control, April 8, 2013
12 Clinical outcomes in patients receiving three lines of targeted therapy for metastatic renal cell carcinoma: Results from a large patient cohort European Journal of Cancer, March 22, 2013
13 Predicted plasma 25-hydroxyvitamin D and risk of renal cell cancer Journal of the National Cancer Institute, April 11, 2013
14 Long-term safety and efficacy of sustained eculizumab treatment in patients with paroxysmal nocturnal haemoglobinuria British Journal of Haematology, April 26, 2013
15 Low serum testosterone levels are predictive of prostate cancer World Journal of Urology, April 9, 2013
16 Aberrant BAF57 Signaling Facilitates Pro-metastatic Phenotypes Clinical Cancer Research, April 1, 2013
17 Clinical judgment versus biomarker prostate cancer gene 3: which is best when determining the need for repeat prostate biopsy? Urology, March 25, 2013
18 Cardiovascular outcomes in patients with locally advanced and metastatic prostate cancer treated with luteinising-hormone-releasing-hormone agonists or transdermal oestrogen: the randomised, phase 2 MRC PATCH trial (PR09) The Lancet Oncology, March 7, 2013
19 Urothelial carcinoma of the bladder and the upper tract: disparate twins The Journal of Urology, April 18, 2013 Review Article
20 A prospective evaluation of VEGF-targeted treatment cessation in metastatic clear cell renal cancer Annals of Oncology, April 19, 2013
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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