Oncology - Renal/Urologic News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (14) Full Text Articles (529) Focus on Renal

Ranked, sorted, and summarized by MDLinx editors from the latest literature

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541 CHD1 is a 5q21 tumor suppressor required for ERG rearrangement in prostate cancer Cancer Research, March 21, 2013 Clinical Article

542 Comparative Efficacy of Sunitinib versus Sorafenib as First-Line Treatment for Patients with Metastatic Renal Cell Carcinoma Chemotherapy, March 21, 2013 Clinical Article

543 Efficacy of Androgen Deprivation Therapy for Localized Prostate Cancer: Analysis of pT0 Evaluated by Radical Prostatectomy Specimen Anticancer Research, March 21, 2013 Clinical Article

544 Delivery of the co-expression plasmid pEndo-Si-Stat3 by attenuated Salmonella serovar typhimurium for prostate cancer treatment Journal of Cancer Research & Clinical Oncology, March 21, 2013 Clinical Article

545 Renal Carcinoma After Childhood Cancer: A Report From the Childhood Cancer Survivor Study Journal of the National Cancer Institute, March 21, 2013 Clinical Article

546 Early versus deferred androgen suppression therapy for patients with lymph node-positive prostate cancer after local therapy with curative intent: a systematic review Full Text BMC Cancer, March 21, 2013 Evidence Based Medicine Review Article

547 Landscape of chromosome number changes in prostate cancer progression World Journal of Urology, March 21, 2013 Clinical Article

548 Meta-analysis of Diffusion-Weighted Magnetic Resonance Imaging in Detecting Prostate Cancer Journal of Computer Assisted Tomography, March 21, 2013 Evidence Based Medicine Review Article

549 Computed Tomography–Guided Renal Tumor Biopsies: Tumor Imaging Features Affecting Sample Adequacy Journal of Computer Assisted Tomography, March 21, 2013 Review Article

550 Hypofractionated helical tomotherapy using 2.5-2.6 Gy daily fractions for localized prostate cancer Clinical and Translational Oncology, March 21, 2013 Clinical Article

551 Immunotherapy and endothelin receptor antagonists for treatment of castration-resistant prostate cancer International Journal of Cancer, March 20, 2013 Clinical Article

552 Statin use and risk of bladder cancer: a meta-analysis Cancer Causes and Control, March 20, 2013

553 Proton beam therapy and localised prostate cancer: current status and controversies British Journal of Cancer, March 20, 2013 Clinical Article

554 Prostate Cancer Detection at Repeat Biopsy: Can Pelvic Phased-array Multiparametric MRI Replace Saturation Biopsy Anticancer Research, March 20, 2013 Clinical Article

555 Phase II Trial Assessing Granulocyte-macrophage-Colony Stimulating Factor, Ketoconazole Plus Mitoxantrone in Metastatic Castration-resistant Prostate Cancer Progressing After Docetaxel Treatments Cancer Investigation, March 20, 2013 Clinical Article

556 PPP2R2C loss promotes castration-resistant prostate cancer growth and is associated with increased prostate cancer-specific mortality Molecular Cancer Research, March 20, 2013 Clinical Article

557 Dihydrotestosterone and Bicalutamide Do Not Affect Periostin Expression in Androgen-dependent LNCaP Prostate Cancer Cell Lines Anticancer Research, March 20, 2013 Clinical Article

558 YB-1 suppression induces STAT3 proteolysis and sensitizes renal cancer to interferon-α Cancer Immunology, Immunotherapy, March 20, 2013 Clinical Article

559 Prostate-specific antigen response after short-term hormone therapy plus external-beam radiotherapy and outcome in patients treated on Radiation Therapy Oncology Group study 9413 Cancer, March 20, 2013 Clinical Article

560 Multi-institutional analysis of sequential intravesical gemcitabine and mitomycin C chemotherapy for non–muscle invasive bladder cancer Urologic Oncology: Seminars and Original Investigations, March 20, 2013 Review Article Clinical Article

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Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 Clinical activity of abiraterone acetate in patients with metastatic castration-resistant prostate cancer progressing after enzalutamide Annals of Oncology, April 19, 2013

2 Antitumour activity of abiraterone acetate against metastatic castration-resistant prostate cancer progressing after docetaxel and enzalutamide (MDV3100) Annals of Oncology, April 16, 2013

3 Gene-Environment Interactions in Bladder Cancer Cancer Research, April 1, 2013

4 Abiraterone and Novel Antiandrogens: Overcoming Castration Resistance in Prostate Cancer Annual Review of Medicine, April 26, 2013 Review Article

5 Ipilimumab alone or in combination with radiotherapy in metastatic castration-resistant prostate cancer: results from an open-label, multicenter phase I/II study Annals of Oncology, April 3, 2013

6 The role of surgery for metastatic renal cell carcinoma in the era of targeted therapies World Journal of Urology, April 2, 2013 Review Article

7 Emerging therapies in metastatic castration-sensitive and castration-resistant prostate cancer Current Opinion in Oncology, April 10, 2013 Review Article

8 Up-regulation of TGM2 with ITGB1 and SDC4 is important in the development and metastasis of renal cell carcinoma Urologic Oncology: Seminars and Original Investigations, April 1, 2013

9 Axitinib versus sorafenib as second-line treatment for advanced renal cell carcinoma: overall survival analysis and updated results from a randomised phase 3 trial The Lancet Oncology, April 24, 2013

10 Advances in bladder cancer imaging BMC Medicine, April 15, 2013 Free full text Review Article

11 Androgen deprivation therapy and the risk of colorectal cancer in patients with prostate cancer Cancer Causes and Control, April 8, 2013

12 Clinical outcomes in patients receiving three lines of targeted therapy for metastatic renal cell carcinoma: Results from a large patient cohort European Journal of Cancer, March 22, 2013

13 Predicted plasma 25-hydroxyvitamin D and risk of renal cell cancer Journal of the National Cancer Institute, April 11, 2013

14 Long-term safety and efficacy of sustained eculizumab treatment in patients with paroxysmal nocturnal haemoglobinuria British Journal of Haematology, April 26, 2013

15 Low serum testosterone levels are predictive of prostate cancer World Journal of Urology, April 9, 2013

16 Aberrant BAF57 Signaling Facilitates Pro-metastatic Phenotypes Clinical Cancer Research, April 1, 2013

17 Clinical judgment versus biomarker prostate cancer gene 3: which is best when determining the need for repeat prostate biopsy? Urology, March 25, 2013

18 Cardiovascular outcomes in patients with locally advanced and metastatic prostate cancer treated with luteinising-hormone-releasing-hormone agonists or transdermal oestrogen: the randomised, phase 2 MRC PATCH trial (PR09) The Lancet Oncology, March 7, 2013

19 Urothelial carcinoma of the bladder and the upper tract: disparate twins The Journal of Urology, April 18, 2013 Review Article

20 A prospective evaluation of VEGF-targeted treatment cessation in metastatic clear cell renal cancer Annals of Oncology, April 19, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more

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Oncology - Renal/Urologic News & Articles

Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology