Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Oncology
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D Scott Cunningham MD, PhD
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501 Intake of fiber and fiber-rich plant foods is associated with a lower risk of renal cell carcinoma in a large US cohort American Journal of Clinical Nutrition, March 25, 2013 Clinical Article
502 Genes associated with prostate cancer are differentially expressed in African American and European American men Cancer Epidemiology, Biomarkers & Prevention, March 25, 2013 Review Article
503 The Chromatin Remodeling Gene ARID1A Is a New Prognostic Marker in Clear Cell Renal Cell Carcinoma American Journal of Pathology, March 25, 2013 Clinical Article
504 Identification of prostate cancer risk categories according to surgical margins status, pathological stage and Gleason score International Journal of Urology, March 25, 2013 Clinical Article
505 Active surveillance of very-low-risk prostate cancer in the setting of active treatment of benign prostatic hyperplasia with 5α-reductase inhibitors Urology, March 25, 2013 Clinical Article
506 Clinical outcomes in patients receiving three lines of targeted therapy for metastatic renal cell carcinoma: Results from a large patient cohort European Journal of Cancer, March 22, 2013 Clinical Article
507 Regulation of several androgen-induced genes through the repression of the miR-99a/let-7c/miR-125b-2 miRNA cluster in prostate cancer cells Oncogene, March 22, 2013 Clinical Article
508 BCA2 is differentially expressed in renal oncocytoma: an analysis of 158 renal neoplasms Tumor Biology, March 22, 2013 Clinical Article
509 Sorafenib Hepatobiliary Disposition: Mechanisms of Hepatic Uptake and Disposition of Generated Metabolites Drug Metabolism and Disposition, March 22, 2013 Clinical Article
510 Safety and efficacy of everolimus in Chinese patients with metastatic renal cell carcinoma resistant to vascular endothelial growth factor receptor-tyrosine kinase inhibitor therapy: an open-label phase 1b study Full Text BMC Cancer, March 22, 2013 Review Article
511 Renal cell carcinoma with IVC and atrial thrombus: A single centres 10 year surgical experience The Surgeon, March 22, 2013 Review Article
512 Statins and prostate cancer recurrence following radical prostatectomy or radiotherapy: a systematic review and meta-analysis Annals of Oncology, March 21, 2013 Review Article Clinical Article
513 Coffee consumption and risk of localized, advanced and fatal prostate cancer: a population-based prospective study Annals of Oncology, March 21, 2013
514 AIB1 predicts bladder cancer outcome and promotes bladder cancer cell proliferation through AKT and E2F1 British Journal of Cancer, March 21, 2013 Clinical Article
515 Extended pelvic lymph node dissection in prostate cancer: a 20-year audit in a single center Annals of Oncology, March 21, 2013 Clinical Article
516 CHD1 is a 5q21 tumor suppressor required for ERG rearrangement in prostate cancer Cancer Research, March 21, 2013 Clinical Article
517 Comparative Efficacy of Sunitinib versus Sorafenib as First-Line Treatment for Patients with Metastatic Renal Cell Carcinoma Chemotherapy, March 21, 2013 Clinical Article
518 Efficacy of Androgen Deprivation Therapy for Localized Prostate Cancer: Analysis of pT0 Evaluated by Radical Prostatectomy Specimen Anticancer Research, March 21, 2013 Clinical Article
519 Delivery of the co-expression plasmid pEndo-Si-Stat3 by attenuated Salmonella serovar typhimurium for prostate cancer treatment Journal of Cancer Research & Clinical Oncology, March 21, 2013 Clinical Article
520 Renal Carcinoma After Childhood Cancer: A Report From the Childhood Cancer Survivor Study Journal of the National Cancer Institute, March 21, 2013 Clinical Article
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 Clinical activity of abiraterone acetate in patients with metastatic castration-resistant prostate cancer progressing after enzalutamide Annals of Oncology, April 19, 2013
2 Antitumour activity of abiraterone acetate against metastatic castration-resistant prostate cancer progressing after docetaxel and enzalutamide (MDV3100) Annals of Oncology, April 16, 2013
3 Gene-Environment Interactions in Bladder Cancer Cancer Research, April 1, 2013
4 Abiraterone and Novel Antiandrogens: Overcoming Castration Resistance in Prostate Cancer Annual Review of Medicine, April 26, 2013 Review Article
5 Ipilimumab alone or in combination with radiotherapy in metastatic castration-resistant prostate cancer: results from an open-label, multicenter phase I/II study Annals of Oncology, April 3, 2013
6 The role of surgery for metastatic renal cell carcinoma in the era of targeted therapies World Journal of Urology, April 2, 2013 Review Article
7 Emerging therapies in metastatic castration-sensitive and castration-resistant prostate cancer Current Opinion in Oncology, April 10, 2013 Review Article
8 Up-regulation of TGM2 with ITGB1 and SDC4 is important in the development and metastasis of renal cell carcinoma Urologic Oncology: Seminars and Original Investigations, April 1, 2013
9 Axitinib versus sorafenib as second-line treatment for advanced renal cell carcinoma: overall survival analysis and updated results from a randomised phase 3 trial The Lancet Oncology, April 24, 2013
10 Advances in bladder cancer imaging BMC Medicine, April 15, 2013 Free full text Review Article
11 Androgen deprivation therapy and the risk of colorectal cancer in patients with prostate cancer Cancer Causes and Control, April 8, 2013
12 Clinical outcomes in patients receiving three lines of targeted therapy for metastatic renal cell carcinoma: Results from a large patient cohort European Journal of Cancer, March 22, 2013
13 Predicted plasma 25-hydroxyvitamin D and risk of renal cell cancer Journal of the National Cancer Institute, April 11, 2013
14 Long-term safety and efficacy of sustained eculizumab treatment in patients with paroxysmal nocturnal haemoglobinuria British Journal of Haematology, April 26, 2013
15 Low serum testosterone levels are predictive of prostate cancer World Journal of Urology, April 9, 2013
16 Aberrant BAF57 Signaling Facilitates Pro-metastatic Phenotypes Clinical Cancer Research, April 1, 2013
17 Clinical judgment versus biomarker prostate cancer gene 3: which is best when determining the need for repeat prostate biopsy? Urology, March 25, 2013
18 Cardiovascular outcomes in patients with locally advanced and metastatic prostate cancer treated with luteinising-hormone-releasing-hormone agonists or transdermal oestrogen: the randomised, phase 2 MRC PATCH trial (PR09) The Lancet Oncology, March 7, 2013
19 Urothelial carcinoma of the bladder and the upper tract: disparate twins The Journal of Urology, April 18, 2013 Review Article
20 A prospective evaluation of VEGF-targeted treatment cessation in metastatic clear cell renal cancer Annals of Oncology, April 19, 2013
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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