Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
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441 Extracts from Epilobium sp. herbs induce apoptosis in human hormone-dependent prostate cancer cells by activating the mitochondrial pathway Journal of Pharmacy and Pharmacology, April 29, 2013 Clinical Article
442 Nephron-sparing Surgery for Renal Cell Carcinoma of the Allograft After Renal Transplantation: Report of Two Cases Transplantation Proceedings, April 29, 2013
443 Large-scale independent validation of the nuclear factor-κB p65 prognostic biomarker in prostate cancer European Journal of Cancer, April 29, 2013 Clinical Article
444 Prostate cancer genomics by high-throughput technologies: genome-wide association study and sequencing analysis Endocrine-Related Cancer, April 29, 2013 Review Article
445 A report of renal artery embolization for hematuria facilitating neoadjuvant chemotherapy in an unresectable malignant renal rhabdoid tumor Pediatric Surgery International, April 29, 2013
446 Rectal culture to isolate fluoroquinolone resistant organisms prior to prostate biopsy: predictive value and concordance Urology Times, April 29, 2013 Clinical Article
447 Is the use of empiric antibiotics for elevated prostate specific antigen a risk factor for infectious complications after transrectal ultrasound-guided prostate biopsy Urology Times, April 29, 2013 Clinical Article
448 Abiraterone and Novel Antiandrogens: Overcoming Castration Resistance in Prostate Cancer Annual Review of Medicine, April 26, 2013 Review Article
449 Long-term safety and efficacy of sustained eculizumab treatment in patients with paroxysmal nocturnal haemoglobinuria British Journal of Haematology, April 26, 2013
450 Concurrent chemoradiotherapy with low dose weekly gemcitabine in medically inoperable muscle-invasive bladder cancer patients Clinical and Translational Oncology, April 26, 2013 Clinical Article
451 Quality of life after prostate cancer treatments in patients comparable at baseline British Journal of Cancer, April 26, 2013 Clinical Article
452 Paradoxical metastatic progression following 3months of neo-adjuvant androgen suppression in the TROG 96.01 trial for men with locally advanced prostate cancer Radiotherapy & Oncology, April 26, 2013 Clinical Article
453 Phyllanthus Suppresses Prostate Cancer Cell, PC-3, Proliferation and Induces Apoptosis through Multiple Signalling Pathways (MAPKs, PI3K/Akt, NFB, and Hypoxia) Full Text Evidence-based Complementary and Alternative Medicine , April 26, 2013 Clinical Article
454 Second line treatment of metastatic renal cell carcinoma: The Institut Gustave Roussy experience with targeted therapies in 251 consecutive patients European Journal of Cancer, April 26, 2013 Clinical Article
455 Clinical outcomes in patients receiving three lines of targeted therapy for metastatic renal cell carcinoma: Results from a large patient cohort European Journal of Cancer, April 26, 2013 Clinical Article
456 Biological determinants of health disparities in prostate cancer Current Opinion in Oncology, April 26, 2013 Review Article
457 Testicular germ cell tumors: biology and clinical update Current Opinion in Oncology, April 26, 2013 Review Article
458 A Phase I Study of Folate Immune Therapy (EC90 Vaccine Administered With GPI-0100 Adjuvant Followed by EC17) in Patients With Renal Cell Carcinoma Journal of Immunotherapy, April 26, 2013 Clinical Article
459 High-resolution ERG-expression profiling on GeneChip exon 1.0 ST arrays in primary and castration-resistant prostate cancer BJU International, April 26, 2013 Clinical Article
460 The role of DAB2IP in androgen receptor activation during prostate cancer progression Oncogene, April 26, 2013 Review Article
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 Mortality after radical prostatectomy or external beam radiotherapy for localized prostate cancer Journal of the National Cancer Institute, May 1, 2013
2 Prognostic factors for survival in 1059 patients treated with sunitinib for metastatic renal cell carcinoma British Journal of Cancer, May 23, 2013
3 Axitinib versus sorafenib as second-line treatment for advanced renal cell carcinoma: overall survival analysis and updated results from a randomised phase 3 trial The Lancet Oncology, May 3, 2013
4 Gleason 6 prostate tumors diagnosed in the PSA era do not demonstrate the capacity for metastatic spread at the time of radical prostatectomy Urology, May 28, 2013
5 NF-kB Inhibition by Bortezomib Permits Interferon-γ-Activated RIP1 Kinase-Dependent Necrosis in Renal Cell Carcinoma. Molecular Cancer Therapeutics, May 13, 2013
6 Assessing the invasive potential of bladder cancer: development and validation of a new preclinical assay The Journal of Urology, May 7, 2013
7 Impact of smoking status on bladder tumor recurrence after radical nephroureterectomy for upper tract urothelial carcinoma The Journal of Urology, May 13, 2013
8 Outcomes in stage I testicular seminoma: A population-based study of 9193 patients Cancer, May 6, 2013
9 PSA screening and deaths from prostate cancer after diagnosis—a population based analysis The Prostate, May 7, 2013
10 Patient-reported genitourinary toxicity for long-term prostate cancer survivors treated with radiation therapy British Journal of Cancer, May 6, 2013
11 Clinical activity of abiraterone acetate in patients with metastatic castration-resistant prostate cancer progressing after enzalutamide Annals of Oncology, April 19, 2013
12 Fibroblast Growth Factor Receptor 3 is a Rational Therapeutic Target in Bladder Cancer Molecular Cancer Therapeutics, May 13, 2013
13 Treatment of local-regional prostate cancer detected by PSA screening: benefits and harms according to prognostic factors British Journal of Cancer, May 17, 2013
14 Relationship of gleason patterns in gleason score 7 prostate cancer Cancer Research, May 24, 2013
15 Intrinsic immune alterations in renal cell carcinoma and emerging immunotherapeutic approaches Expert Opinion on Biological Therapy, May 30, 2013 Review Article
16 Safety and toxicity of saw palmetto in the camus trial The Journal of Urology, April 22, 2013
17 A phase II trial of neoadjuvant nab-paclitaxel, carboplatin, and gemcitabine (ACAG) in patients with locally advanced carcinoma of the bladder Urology, May 24, 2013
18 Prevalence of the metabolic syndrome and cardiovascular disease risk in chemotherapy-treated testicular germ cell tumour survivors British Journal of Cancer, May 13, 2013
19 Associations of tea and coffee consumption with prostate cancer risk Cancer Causes and Control, April 23, 2013
20 Prolonged exposure to tyrosine kinase inhibitors or early use of everolimus in metastatic renal cell carcinoma: are the two options alike Medical Oncology, April 30, 2013
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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