Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Oncology
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D Scott Cunningham MD, PhD
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1 Circulating adipokine levels and endometrial cancer risk in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial Cancer Epidemiology, Biomarkers & Prevention, May 24, 2013
2 Cardiovascular risk factors among long-term survivors of breast, prostate, colorectal, and gynecologic cancers: a gap in survivorship care? Journal of Cancer Survivorship, May 24, 2013 Review Article
3 Locally advanced vulvar cancer in elderly women: is chemoradiation beneficial? American Journal of Clinical Oncology, May 24, 2013 Evidence Based Medicine
4 A phase II study of weekly neoadjuvant chemotherapy followed by radical chemoradiation for locally advanced cervical cancer British Journal of Cancer, May 23, 2013
5 A prospective investigation of fish, meat and cooking-related carcinogens with endometrial cancer incidence British Journal of Cancer, May 23, 2013
6 Nuclear TK1 expression is an independent prognostic factor for survival in pre-malignant and malignant lesions of the cervix Full Text BMC Cancer, May 23, 2013 Clinical Article
7 An insulin-like growth factor-II intronic variant affects local DNA conformation and ovarian cancer survival Carcinogenesis, May 23, 2013 Clinical Article
8 Apolipoprotein concentrations are elevated in malignant ovarian cyst fluids suggesting that lipoprotein metabolism is dysregulated in epithelial ovarian cancer Cancer Investigation, May 23, 2013 Clinical Article
9 Early telomere shortening and genomic instability in tubo-ovarian preneoplastic lesions Clinical Cancer Research, May 22, 2013
10 Clinical outcomes of image guided radiation therapy (IGRT) with gold fiducial vaginal cuff markers for high-risk endometrial cancer Acta Oncologica, May 22, 2013 Clinical Article
11 Progesterone enhances calcitriol antitumor activity by upregulating vitamin D receptor expression and promoting apoptosis in endometrial cancer cells Cancer Prevention Research, May 22, 2013 Clinical Article
12 WAVE1 gene silencing via RNA interference reduces ovarian cancer cell invasion, migration and proliferation Gynecologic Oncology, May 22, 2013 Clinical Article
13 Communicating risk of hereditary breast and ovarian cancer with an interactive decision support tool Patient Education and Counselling, May 22, 2013 Review Article
14 HPV genotypes and risk of precancer Cancer Epidemiology, Biomarkers & Prevention, May 21, 2013
15 Mutational analysis of BRCA1 and BRCA2 in hereditary breast and ovarian cancer families from Asturias Full Text BMC Cancer, May 21, 2013 Clinical Article
16 Poor Interobserver Reproducibility in the Diagnosis of High-grade Endometrial Carcinoma American Journal of Surgical Pathology , May 21, 2013 Review Article
17 Expression and Functional Pathway Analysis of Nuclear Receptor NR2F2 in Ovarian Cancer Journal of Clinical Endocrinology and Metabolism, May 21, 2013 Review Article
18 Hormonal and reproductive risk factors for sporadic microsatellite stable and unstable endometrial tumors Cancer Epidemiology, Biomarkers & Prevention, May 20, 2013
19 The size of the metastatic lymph node is an independent prognostic factor for the patients with cervical cancer treated by definitive radiotherapy Radiotherapy & Oncology, May 20, 2013 Review Article
20 HDR brachytherapy combined with interstitial hyperthermia in locally advanced cervical cancer patients initially treated with concomitant radiochemotherapy - a phase III study Radiotherapy & Oncology, May 20, 2013 Review Article
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 Human papillomavirus testing versus repeat cytology for triage of minor cytological cervical lesions Cochrane Reviews, April 1, 2013 Review Article
2 Prophylactic salpingectomy in premenopausal low-risk women for ovarian cancer: primum non nocere Gynecologic Oncology, April 9, 2013
3 Prognostic factors for stage III epithelial ovarian cancer treated with intraperitoneal chemotherapy: A Gynecologic Oncology Group Study Gynecologic Oncology, April 18, 2013
4 Tubulin-beta-III overexpression by uterine serous carcinomas is a marker for poor overall survival after platinum/taxane chemotherapy and sensitivity to epothilones Cancer, April 22, 2013
5 Early detection of ovarian cancer American Journal of Obstetrics and Gynecology, April 18, 2013 Review Article
6 Standard chemotherapy with or without bevacizumab in advanced ovarian cancer: quality-of-life outcomes from the International Collaboration on Ovarian Neoplasms (ICON7) phase 3 randomised trial The Lancet Oncology, March 14, 2013
7 High-grade vaginal intraepithelial neoplasia: can we be selective about who we treat? BJOG: An International Journal of Obstetrics and Gynaecology, April 4, 2013
8 Abagovomab as maintenance therapy in patients with epithelial ovarian cancer: a phase III trial of the AGO OVAR, COGI, GINECO, and GEICO--The Mimosa Study Journal of Clinical Oncology, March 15, 2013
9 The role of the fallopian tube in the origin of ovarian cancer American Journal of Obstetrics and Gynecology, April 18, 2013
10 Positive peritoneal cytology is highly predictive of prognosis and relapse patterns in stage III (FIGO 2009) endometrial cancer Gynecologic Oncology, April 26, 2013
11 Controversies of the Hormonal Conservative Treatment of Endometrial Cancer Gynecologic and Obstetric Investigation, April 1, 2013
12 An international assessment of ovarian cancer incidence and mortality Gynecologic Oncology, April 9, 2013
13 A Review of Dietary Prevention of Human Papillomavirus-Related Infection of the Cervix and Cervical Intraepithelial Neoplasia Nutrition and Cancer, April 1, 2013
14 Vascular endothelial growth factor (VEGF) improves the sensitivity of CA125 for differentiation of epithelial ovarian cancers from ovarian cysts Archives of Gynecology and Obstetrics, April 10, 2013
15 Controversies of the Hormonal Conservative Treatment of Endometrial Cancer Gynecologic and Obstetric Investigation, April 12, 2013 Review Article
16 Neoadjuvant chemotherapy prior to pelvic exenteration in patients with recurrent cervical cancer: Single institution experience Gynecologic Oncology, March 12, 2013
17 Fertility treatment and childhood cancer risk: A systematic meta-analysis Fertility and Sterility, April 8, 2013 Evidence Based Medicine Review Article
18 Outcome of stage IB2-IIB patients with bulky uterine cervical cancer who underwent neoadjuvant chemotherapy followed by radical hysterectomy International Journal of Clinical Oncology, April 19, 2013
19 Brachytherapy versus radical hysterectomy after external beam chemoradiation with gemcitabine plus cisplatin: a randomized, phase III study in IB2-IIB cervical cancer patients Annals of Oncology, April 29, 2013
20 Silencing of human papillomavirus (HPV) E6/E7 oncogene expression affects both the contents and amounts of extracellular microvesicles released from HPV-positive cancer cells International Journal of Cancer, April 1, 2013
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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