Gynecologic Oncology News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (5) Full Text Articles (316) Focus on Head & neck

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

141 Diagnostic accuracy of preoperative alpha-fetoprotein as an ovarian tumor marker in children and adolescents: not as good as we thought? Pediatric Surgery International, May 14, 2013 Clinical Article

142 Sentinel lymph node in endometrial cancer: an overview Gynecological Surgery, May 14, 2013 Review Article

143 Nutritional status, CT body composition measures and survival in ovarian cancer Gynecologic Oncology, May 13, 2013 Clinical Article

144 Individual and geographic disparities in human papillomavirus types 16/18 in high-grade cervical lesions Cancer, May 13, 2013 Clinical Article

145 Expression of HPV16 E5 down-modulates the TGFbeta signaling pathway Full Text Molecular Cancer, May 13, 2013 Clinical Article

146 Comparative outcomes assessment of uterine grade 3 endometrioid, serous, and clear cell carcinomas Gynecologic Oncology, May 13, 2013 Clinical Article

147 Expression of steroid receptor coactivator 3 in ovarian epithelial cancer is a poor prognostic factor and a marker for platinum resistance British Journal of Cancer, May 10, 2013

148 Autoantibodies to MUC1 glycopeptides cannot be used as a screening assay for early detection of breast, ovarian, lung or pancreatic cancer British Journal of Cancer, May 10, 2013

149 The Patient Protection and Affordable Care Act: Impact on the care of Gynecologic Oncology patients in the absence of Medicaid expansion in Central Virginia Gynecologic Oncology, May 10, 2013 Review Article

150 Decreased expression of BTG3 was linked to carcinogenesis, aggressiveness, and prognosis of ovarian carcinoma Tumor Biology, May 10, 2013 Clinical Article

151 Cytokine Patterns Differ Seasonally between Women with and without Uterine Leiomyomata American Journal of Reproductive Immunology, May 10, 2013 Clinical Article

152 Upregulation of microRNA-224 is associated with aggressive progression and poor prognosis in human cervical cancer Full Text Diagnostic Pathology, May 10, 2013 Clinical Article

153 Claudin-18 over expression in intestinal-type mutinous borderline tumor of the ovary Histopathology, May 10, 2013 Clinical Article

154 Ovarian cancer incidence trends in relation to changing patterns of menopausal hormone therapy use in the United States Journal of Clinical Oncology, May 9, 2013

155 Patients' and oncologists' views on the treatment and care of advanced ovarian cancer in the UK: results from the ADVOCATE study British Journal of Cancer, May 9, 2013 Review Article

156 Involved-Field Radiation Therapy for Locoregionally Recurrent Ovarian Cancer Gynecologic Oncology, May 9, 2013 Clinical Article

157 Role of preoperative MR imaging in the evaluation of patients with persistent or recurrent gynaecological malignancies before pelvic exenteration European Radiology, May 9, 2013 Clinical Article

158 Physiological 18F-FDG uptake patterns in female reproductive organs before and after chemotherapy treatments: assessment by PET/CT Medical Oncology, May 9, 2013 Clinical Article

159 Prospective, Multi-center Randomized Intermediate Biomarker Study of Oral Contraceptive vs. Depo-Provera for Prevention of Endometrial Cancer in Women with Lynch Syndrome Cancer Prevention Research, May 8, 2013 Clinical Article

160 Evaluation of Exposures to Healthcare Personnel from Cisplatin during a Mock Demonstration of Intra-operative Intraperitoneal Chemotherapy Administration Gynecologic Oncology, May 8, 2013 Clinical Article

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Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 Phase III randomised controlled trial of neoadjuvant chemotherapy plus radical surgery vs radical surgery alone for stages IB2, IIA2, and IIB cervical cancer: a Japan Clinical Oncology Group trial (JCOG 0102) British Journal of Cancer, May 6, 2013

2 Accuracy of Positron Emission Tomography/Computed Tomography in the Diagnosis and Restaging for Recurrent Ovarian Cancer: A Meta-Analysis International Journal of Gynecological Cancer, April 29, 2013 Evidence Based Medicine Review Article

3 First-line paclitaxel and carboplatin in persistent/recurrent or advanced cervical cancer: a retrospective analysis of patients treated at brazilian national cancer institute International Journal of Gynecological Cancer, May 6, 2013

4 A phase II trial of docetaxel and bevacizumab in recurrent ovarian cancer within 12 months of prior platinum-based chemotherapy Gynecologic Oncology, May 7, 2013

5 Tubal ligation, hysterectomy, and epithelial ovarian cancer in the New England case-control study International Journal of Cancer, May 7, 2013

6 Prophylactic salpingectomy in premenopausal low-risk women for ovarian cancer: primum non nocere Gynecologic Oncology, April 9, 2013

7 Predictors of recovery of ovarian function during aromatase inhibitor therapy Annals of Oncology, May 6, 2013

8 A phase II study of modified dose-dense paclitaxel and every 4-week carboplatin for the treatment of advanced-stage primary epithelial ovarian, fallopian tube, or peritoneal carcinoma Cancer Chemotherapy and Pharmacology, May 15, 2013

9 A phase II study of weekly neoadjuvant chemotherapy followed by radical chemoradiation for locally advanced cervical cancer British Journal of Cancer, May 23, 2013

10 Locally advanced vulvar cancer in elderly women: is chemoradiation beneficial? American Journal of Clinical Oncology, May 24, 2013 Evidence Based Medicine

11 Ovarian cancer incidence trends in relation to changing patterns of menopausal hormone therapy use in the United States Journal of Clinical Oncology, May 9, 2013

12 Nutritional status, CT body composition measures and survival in ovarian cancer Gynecologic Oncology, May 13, 2013

13 Endocervical glandular involvement, multicentricity, and extent of the disease are features of high-grade cervical intraepithelial neoplasia Annals of Diagnostic Pathology, May 15, 2013

14 HPV genotypes and risk of precancer Cancer Epidemiology, Biomarkers & Prevention, May 21, 2013

15 Autoantibodies to MUC1 glycopeptides cannot be used as a screening assay for early detection of breast, ovarian, lung or pancreatic cancer British Journal of Cancer, May 10, 2013

16 Prognostic factors for stage III epithelial ovarian cancer treated with intraperitoneal chemotherapy: A Gynecologic Oncology Group Study Gynecologic Oncology, April 18, 2013

17 Impact of tumor size on survival in cancer of the cervix and validation of stage IIA1 and IIA2 subdivisions Gynecologic Oncology, May 15, 2013

18 Preserved foods associated with increased risk of ovarian cancer Gynecologic Oncology, May 15, 2013

19 Total laparoscopic radical trachelectomy in the treatment of early squamous cell cervical cancer: A retrospective study with 8-year follow-up Gynecologic Oncology, May 8, 2013

20 Physiological 18F-FDG uptake patterns in female reproductive organs before and after chemotherapy treatments: assessment by PET/CT Medical Oncology, May 9, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more

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Gynecologic Oncology News & Articles

Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology