Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
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281 Metformin and the risk of endometrial cancer: A case-control analysis Gynecologic Oncology, March 25, 2013 Clinical Article
282 Risk of gestational trophoblastic neoplasia after hCG normalisation according to hydatidiform mole type Gynecologic Oncology, March 25, 2013 Clinical Article
283 2012 Updated Consensus Guidelines for the Management of Abnormal Cervical Cancer Screening Tests and Cancer Precursors Obstetrics and Gynecology, March 25, 2013 Clinical Guideline
284 The relationship between tumor size and stage in early versus advanced ovarian cancer Medical Hypotheses, March 25, 2013 Review Article
285 Taxane-sensitivity of ovarian carcinomas previously treated with paclitaxel and carboplatin Cancer Chemotherapy and Pharmacology, March 25, 2013 Clinical Article
286 Undifferentiated Endometrial Carcinoma: A Diagnosis Frequently Overlooked Full Text Archives of Pathology & Laboratory Medicine, March 25, 2013 Review Article
287 Epigenetic analysis of the Notch superfamily in high-grade serous ovarian cancer Gynecologic Oncology, March 25, 2013 Clinical Article
288 Implementing specificity of HPV-DNA primary screening in a successful organised cervical cancer prevention programme Gynecologic Oncology, March 25, 2013 Review Article Clinical Article
289 A clinicopathological and immunohistochemical study of minimal deviation adenocarcinoma of the uterine cervix Medical Hypotheses, March 25, 2013 Clinical Article
290 Conservative treatment for complex neonatal ovarian cysts: A long-term follow-up analysis Journal of Pediatric Surgery, March 25, 2013 Clinical Article
291 Retrospective analysis of prognostic variables and clinical outcomes in surgically staged intermediate risk endometrial carcinoma European Journal of Obstetrics & Gynecology and Reproductive Biology, March 22, 2013 Clinical Article
292 The endoplasmic reticulum stress marker, glucose-regulated protein-78 (GRP78) in visceral adipocytes predicts endometrial cancer progression and patient survival Gynecologic Oncology, March 22, 2013 Clinical Article
293 Upfront Treatment of Locally Advanced Cervical Cancer with Intensity Modulated Radiation Therapy Compared to Four-Field Radiation Therapy: A Cost-Effectiveness Analysis Gynecologic Oncology, March 22, 2013 Clinical Article
294 HPV-16 E6 and E7 protein T cell epitopes prediction analysis based on distributions of HLA-A loci across populations: An in silico approach Vaccine , March 22, 2013 Review Article
295 Administration of PLGA nanoparticles carrying shRNA against focal adhesion kinase and CD44 results in enhanced antitumor effects against ovarian cancer Cancer Gene Therapy, March 22, 2013 Clinical Article
296 Chinese women's motivation to receive future screening: The role of social-demographic factors, knowledge and risk perception of cervical cancer European Journal of Oncology Nursing , March 22, 2013 Clinical Article
297 Acute phlegmonous esophagitis as a rare but threatening complication of chemoradiotherapy: report of a case Surgery Today, March 22, 2013
298 A pilot study of oxaliplatin with oral S-1 as second-line chemotherapy for patients with recurrent adenocarcimona of the uterine cervix International Journal of Clinical Oncology, March 21, 2013 Clinical Article
299 Long-term prospective longitudinal evaluation of emotional distress and quality of life in cervical cancer patients who remained disease-free 2-years from diagnosis Full Text BMC Cancer, March 21, 2013 Clinical Article
300 Validated gene targets associated with curatively treated advanced serous ovarian carcinoma Gynecologic Oncology, March 21, 2013 Clinical Article
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 Human papillomavirus testing versus repeat cytology for triage of minor cytological cervical lesions Cochrane Reviews, April 1, 2013 Review Article
2 Prophylactic salpingectomy in premenopausal low-risk women for ovarian cancer: primum non nocere Gynecologic Oncology, April 9, 2013
3 Prognostic factors for stage III epithelial ovarian cancer treated with intraperitoneal chemotherapy: A Gynecologic Oncology Group Study Gynecologic Oncology, April 18, 2013
4 Tubulin-beta-III overexpression by uterine serous carcinomas is a marker for poor overall survival after platinum/taxane chemotherapy and sensitivity to epothilones Cancer, April 22, 2013
5 Early detection of ovarian cancer American Journal of Obstetrics and Gynecology, April 18, 2013 Review Article
6 Standard chemotherapy with or without bevacizumab in advanced ovarian cancer: quality-of-life outcomes from the International Collaboration on Ovarian Neoplasms (ICON7) phase 3 randomised trial The Lancet Oncology, March 14, 2013
7 High-grade vaginal intraepithelial neoplasia: can we be selective about who we treat? BJOG: An International Journal of Obstetrics and Gynaecology, April 4, 2013
8 Abagovomab as maintenance therapy in patients with epithelial ovarian cancer: a phase III trial of the AGO OVAR, COGI, GINECO, and GEICO--The Mimosa Study Journal of Clinical Oncology, March 15, 2013
9 The role of the fallopian tube in the origin of ovarian cancer American Journal of Obstetrics and Gynecology, April 18, 2013
10 Positive peritoneal cytology is highly predictive of prognosis and relapse patterns in stage III (FIGO 2009) endometrial cancer Gynecologic Oncology, April 26, 2013
11 Controversies of the Hormonal Conservative Treatment of Endometrial Cancer Gynecologic and Obstetric Investigation, April 1, 2013
12 An international assessment of ovarian cancer incidence and mortality Gynecologic Oncology, April 9, 2013
13 A Review of Dietary Prevention of Human Papillomavirus-Related Infection of the Cervix and Cervical Intraepithelial Neoplasia Nutrition and Cancer, April 1, 2013
14 Vascular endothelial growth factor (VEGF) improves the sensitivity of CA125 for differentiation of epithelial ovarian cancers from ovarian cysts Archives of Gynecology and Obstetrics, April 10, 2013
15 Controversies of the Hormonal Conservative Treatment of Endometrial Cancer Gynecologic and Obstetric Investigation, April 12, 2013 Review Article
16 Neoadjuvant chemotherapy prior to pelvic exenteration in patients with recurrent cervical cancer: Single institution experience Gynecologic Oncology, March 12, 2013
17 Fertility treatment and childhood cancer risk: A systematic meta-analysis Fertility and Sterility, April 8, 2013 Evidence Based Medicine Review Article
18 Outcome of stage IB2-IIB patients with bulky uterine cervical cancer who underwent neoadjuvant chemotherapy followed by radical hysterectomy International Journal of Clinical Oncology, April 19, 2013
19 Brachytherapy versus radical hysterectomy after external beam chemoradiation with gemcitabine plus cisplatin: a randomized, phase III study in IB2-IIB cervical cancer patients Annals of Oncology, April 29, 2013
20 Silencing of human papillomavirus (HPV) E6/E7 oncogene expression affects both the contents and amounts of extracellular microvesicles released from HPV-positive cancer cells International Journal of Cancer, April 1, 2013
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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