Oncology - Pharmacology/Therapy News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (21) Full Text Articles (1643) Focus on Hematology

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

1 Limited impact of prognostic factors in patients with recurrent glioblastoma multiforme treated with a bevacizumab-based regimen Journal of Neuro-Oncology, June 19, 2013 Clinical Article

2 Fludarabine/2 gy tbi is superior to 2 gy TBI as conditioning for HLA-matched related hct: a phase III randomized trial Biology of Blood and Marrow Transplantation, June 19, 2013 Clinical Article

3 Phase II study of weekly PM00104 (ZALYPSIS) in patients with pretreated advanced/metastatic endometrial or cervical cancer Medical Oncology, June 19, 2013 Clinical Article

4 Cytarabine, Ki-67, and SOX11 in patients with mantle cell lymphoma receiving rituximab-containing autologous stem cell transplantation during first remission Cancer, June 19, 2013 Clinical Article

5 Identification and analysis of in vivo vegf downstream markers link VEGF pathway activity with efficacy of anti-VEGF therapies Clinical Cancer Research, June 19, 2013 Clinical Article

6 Atr inhibition broadly sensitizes ovarian cancer cells to chemotherapy independent of BRCA status Cancer Research, June 19, 2013 Clinical Article

7 Central nervous system involvement with multiple myeloma: long term survival can be achieved with radiation, intrathecal chemotherapy, and immunomodulatory agents British Journal of Haematology, June 19, 2013 Clinical Article

8 Treatment options for esophageal squamous cell carcinoma Expert Opinion on Pharmacotherapy, June 19, 2013 Review Article

9 Prognostic value of complete response in patients with muscle-invasive bladder cancer undergoing concurrent chemoradiotherapy Anticancer Research, June 19, 2013 Clinical Article

10 Prognostic impact of tumor IL-6 expression after preoperative chemoradiotherapy in patients with advanced esophageal squamous cell carcinoma Anticancer Research, June 19, 2013 Clinical Article

11 CD147 mediates chemoresistance in breast cancer via ABCG2 by affecting its cellular localization and dimerization Cancer Letters, June 19, 2013 Clinical Article

12 Salinomycin inhibits Akt/NF-kB and induces apoptosis in cisplatin resistant ovarian cancer cells Cancer Epidemiology, June 19, 2013 Clinical Article

13 Long-term outcomes of primary ocular adnexal lymphoma treatment with intraorbital rituximab injections Journal of Cancer Research & Clinical Oncology, June 19, 2013 Clinical Article

14 Anti-tumor impact of p14ARF on gefitinib-resistant non-small cell lung cancers Molecular Cancer Therapeutics, June 19, 2013 Clinical Article

15 miR-375 is upregulated in acquired paclitaxel resistance in cervical cancer British Journal of Cancer, June 19, 2013 Clinical Article

16 Phase 2 trial of afatinib, an ErbB family blocker, in solid tumors genetically screened for target activation Cancer, June 19, 2013 Clinical Article

17 Ipilimumab and its toxicities: a multidisciplinary approach Full Text The Oncologist, June 19, 2013 Clinical Article

18 Unjustified prescribing of CYP2D6 inhibiting SSRIs in women treated with tamoxifen Breast Cancer Research and Treatment, June 19, 2013 Clinical Article

19 Combination phase II study of weekly paclitaxel and 5'-DFUR for unresectable or recurrent gastric cancer Anticancer Research, June 19, 2013 Clinical Article

20 A multicenter, randomized, active-controlled study to investigate the efficacy and safety of intravenous ferric carboxymaltose in patients with iron deficiency anemia Transfusion, June 19, 2013

50 available pages FirstPrevious 1 2 3 4 5 6 7 8 9 10 Next Last

Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Oncology - Pharmacology/Therapy News & Articles

Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology