Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
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61 TMEPAI regulates EMT in lung cancer cells by modulating the ROS and IRS-1 signaling pathways Carcinogenesis, June 13, 2013 Clinical Article
62 Metabolic alterations in lung cancer–associated fibroblasts correlated with increased glycolytic metabolism of the tumor Molecular Cancer Research, June 13, 2013 Clinical Article
63 Spiritual well-being in lung cancer survivors Supportive Care in Cancer, June 13, 2013 Review Article Clinical Article
64 Association between the XRCC3 C241T polymorphism and lung cancer risk in the Asian population Tumor Biology, June 13, 2013 Evidence Based Medicine Review Article
65 The impact of cigarette smoking on the frequency of and qualitative differences in kras mutations in korean patients with lung adenocarcinoma Full Text Yonsei Medical Journal, June 13, 2013 Clinical Article
66 Pharmacogenomic assessment of outcomes of pemetrexed-treated patients with adenocarcinoma of the lung Full Text Yonsei Medical Journal, June 13, 2013 Clinical Article
67 Radiotherapy promises: focus on lung cancer Bulletin du Cancer, June 13, 2013 Clinical Article
68 The hsp90 inhibitor nvp-auy922 potently inhibits non–small cell lung cancer growth Molecular Cancer Therapeutics, June 13, 2013 Clinical Article
69 Hgf as a circulating biomarker of onartuzumab treatment in patients with advanced solid tumors Molecular Cancer Therapeutics, June 13, 2013 Clinical Article
70 Epigenetic therapy in lung cancer Frontiers in Oncology, June 13, 2013 Review Article
71 The increment in standardized uptake value determined using dual-phase 18F-FDG PET is a promising prognostic factor in non-small-cell lung cancer European Journal of Nuclear Medicine & Molecular Imaging, June 13, 2013 Clinical Article
72 Extensive ossification of thymoma in a child Annals of Thoracic Surgery, June 13, 2013
73 Predictive models for customizing chemotherapy in advanced non-small cell lung cancer (NSCLC) Full Text Translational Lung Cancer Research, June 13, 2013
74 USP8 is a novel target for overcoming gefitinib-resistance in lung cancer Clinical Cancer Research, June 12, 2013
75 Plasma sphingolipids as markers of future lung cancer risk: A population-based, nested case-control study Cancer Epidemiology, Biomarkers & Prevention, June 12, 2013
76 Underuse of hospice care by medicaid-insured patients with stage IV lung cancer in New York and California Journal of Clinical Oncology, June 12, 2013 Clinical Article
77 Treatment of multiple primary lung cancers using stereotactic radiotherapy, either with or without surgery Radiotherapy & Oncology, June 12, 2013 Clinical Article
78 Different impact of il10 haplotype on prognosis in lung squamous cell carcinoma and adenocarcinoma Anticancer Research, June 12, 2013 Clinical Article
79 Carboxy-terminal telopeptide (CTX) and amino-terminal propeptide (PINP) of type i collagen as markers of bone metastases in patients with non-small cell lung cancer Anticancer Research, June 12, 2013 Clinical Article
80 Feedback loop between p66Shc and Nrf2 promotes lung cancer progression Cancer Letters, June 12, 2013 Clinical Article
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 Pemetrexed versus erlotinib in pretreated patients with advanced non-small cell lung cancer: A Hellenic Oncology Research Group (HORG) randomized phase 3 study Cancer, May 13, 2013
2 Intratumour variation of biomarker expression by immunohistochemistry in resectable non-small cell lung cancer European Journal of Cancer, May 6, 2013
3 The optimal duration of vitamin supplementation prior to the first dose of pemetrexed in patients with non-small-cell lung cancer Lung Cancer, May 20, 2013 Review Article
4 Detection of circulating tumor cells harboring a unique ALK rearrangement in ALK-positive non-small-cell lung cancer Journal of Clinical Oncology, May 17, 2013
5 Surrogate endpoints for overall survival in chemotherapy and radiotherapy trials in operable and locally advanced lung cancer: a re-analysis of meta-analyses of individual patients data The Lancet Oncology, May 15, 2013 Review Article
6 Magnetic Resonance Imaging for Lung Cancer Journal of Thoracic Imaging, April 29, 2013 Review Article
7 Phase 2 study of sorafenib in malignant mesothelioma previously treated with platinum-containing chemotherapy Journal of Thoracic Oncology, May 21, 2013
8 Accelerated hyperfractionated radiotherapy within trimodality therapy concepts for stage IIIA/B non-small cell lung cancer: Markedly higher rate of pathologic complete remissions than with conventional fractionation European Journal of Cancer, April 26, 2013
9 Randomized phase III trial of gemcitabine and cisplatin vs. gemcitabine alone in patients with advanced non-small cell lung cancer and a performance status of 2: The CAPPA-2 study Lung Cancer, May 8, 2013
10 Thalidomide versus active supportive care for maintenance in patients with malignant mesothelioma after first-line chemotherapy (NVALT 5): an open-label, multicentre, randomised phase 3 study The Lancet Oncology, May 3, 2013
11 Real-World Effectiveness of Systemic Agents Approved for Advanced Non-Small Cell Lung Cancer: A SEER-Medicare Analysis The Oncologist, May 6, 2013 Free full text
12 Randomized phase II trial of uracil/tegafur and cisplatin versus vinorelbine and cisplatin with concurrent thoracic radiotherapy for locally advanced unresectable stage III non-small-cell lung cancer: NJLCG 0601 Lung Cancer, May 7, 2013
13 Anaplastic lymphoma kinase (ALK) gene rearrangement in non-small cell lung cancer (NSCLC): Results of a multi-centre ALK-testing Lung Cancer, May 16, 2013
14 The ubiquitin-CXCR4 axis plays an important role in acute lung-infection-enhanced lung tumor metastasis Clinical Cancer Research, May 23, 2013
15 Proposal on incorporating blood vessel invasion into the T classification parts as a practical staging system for stage I non-small cell lung cancer Lung Cancer, May 16, 2013
16 Impact of EGFR Inhibitor in Non-Small Cell Lung Cancer on Progression-Free and Overall Survival: A Meta-Analysis Journal of the National Cancer Institute, April 19, 2013 Evidence Based Medicine
17 Variability in the treatment of elderly patients with stage IIIa (n2) non-small-cell lung cancer Journal of Thoracic Oncology, May 20, 2013
18 A phase I pharmacokinetic study of matuzumab in combination with paclitaxel in patients with EGFR-expressing advanced non-small cell lung cancer Investigational New Drugs, May 8, 2013
19 Role of ultrasound-guided transbronchial biopsy in the diagnosis of peripheral pulmonary lesions Lung Cancer, May 6, 2013
20 Randomized international phase III trial of ERCC1 and RRM1 expression-based chemotherapy versus gemcitabine/carboplatin in advanced non-small-cell lung cancer Journal of Clinical Oncology, May 24, 2013
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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