Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
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1 Circulating levels of immune and inflammatory markers and long versus short survival in early-stage lung cancer Annals of Oncology, May 21, 2013
2 Histology and smoking status predict survival of patients with advanced non-small-cell lung cancer: results of West Japan Oncology Group (WJOG) Study 3906l Journal of Thoracic Oncology, May 21, 2013
3 Phase 2 study of sorafenib in malignant mesothelioma previously treated with platinum-containing chemotherapy Journal of Thoracic Oncology, May 21, 2013 Clinical Article
4 Rapid increase of serum neuron specific enolase level and tachyphylaxis of EGFR-tyrosine kinase inhibitor indicate small cell lung cancer transformation from EGFR positive lung adenocarcinoma? Lung Cancer, May 21, 2013
5 Heme-related gene expression signatures of meat intakes in lung cancer tissues Molecular Carcinogenesis, May 21, 2013 Clinical Article
6 Numblike regulates proliferation, apoptosis, and invasion of lung cancer cell Tumor Biology, May 21, 2013 Clinical Article
7 The co-expression of ERβ2 and IL-12Rβ2 is better prognostic factor in non-small-cell lung cancer progression Medical Oncology, May 21, 2013 Clinical Article
8 Tumor cavitation among lung cancer patients receiving first-line chemotherapy at a tertiary care centre in India: association with histology and overall survival Medical Oncology, May 21, 2013 Clinical Article
9 Radiographic Evaluation of the Patient With Lung Cancer: Surgical Implications of Imaging Current Problems in Diagnostic Radiology, May 21, 2013 Clinical Article
10 Pulmonary adenofibroma in a middle-aged man: report of a case Surgery Today, May 21, 2013
11 Intrapleural chemotherapy improves the survival of non-small cell lung cancer patients with positive pleural lavage cytology Surgery Today, May 21, 2013 Clinical Article
12 Tumor Heterogeneity as measured on the CT component of PET/CT Predicts Survival in Patients with Potentially Curable Non-Small Cell Lung Cancer Clinical Cancer Research, May 20, 2013 Clinical Article
13 Association between genetic variants in pre-microRNAs and survival of early-stage NSCLC Journal of Thoracic Oncology, May 20, 2013
14 Variability in the treatment of elderly patients with stage IIIa (n2) non-small-cell lung cancer Journal of Thoracic Oncology, May 20, 2013 Clinical Article
15 The optimal duration of vitamin supplementation prior to the first dose of pemetrexed in patients with non-small-cell lung cancer Lung Cancer, May 20, 2013 Review Article
16 The CD36 dynamic change after radiation therapy in lung cancer patients and its correlation with symptomatic radiation pneumonitis Radiotherapy & Oncology, May 20, 2013 Review Article
17 PTTG1 Promotes Migration and Invasion of Human Non-small Cell Lung Cancer Cells and is modulated by miR-186 Carcinogenesis, May 20, 2013 Clinical Article
18 Lung Cancer Detection with Digital Chest Tomosynthesis: Baseline Results from the Observational Study SOS Journal of Thoracic Oncology, May 20, 2013 Review Article
19 Epidermal Growth Factor Receptor Mutations in Lung Adenocarcinoma in Malaysian Patients Journal of Thoracic Oncology, May 20, 2013 Review Article
20 Clinicopathological features of thymic carcinomas and the impact of histopathological agreement on prognostical studies European Journal of Cardio-Thoracic Surgery, May 20, 2013 Review Article
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 Radiotherapy for lung tumors arising after a prior pneumonectomy Journal of Thoracic Disease, April 8, 2013 Free full text
2 Comparative effectiveness of three platinum-doublet chemotherapy regimens in elderly patients with advanced non-small cell lung cancer Cancer, April 10, 2013
3 Impact of EGFR Inhibitor in Non-Small Cell Lung Cancer on Progression-Free and Overall Survival: A Meta-Analysis Journal of the National Cancer Institute, April 19, 2013 Evidence Based Medicine
4 Prediagnosis soy food consumption and lung cancer survival in women Journal of Clinical Oncology, April 1, 2013
5 Thymidylate synthase and ERCC1 as predictive markers in patients with pulmonary adenocarcinoma treated with pemetrexed and cisplatin Lung Cancer, April 2, 2013
6 Thalidomide versus active supportive care for maintenance in patients with malignant mesothelioma after first-line chemotherapy (NVALT 5): an open-label, multicentre, randomised phase 3 study The Lancet Oncology, April 18, 2013
7 The effectiveness of erlotinib against brain metastases in non-small cell lung cancer patients American Journal of Clinical Oncology, March 28, 2013
8 Diabetes mellitus as an independent risk factor for lung cancer: A meta-analysis of observational studies European Journal of Cancer, April 11, 2013 Review Article
9 Efficacy and safety of albumin-bound paclitaxel in treating recurrent advanced non-small-cell lung cancer Chinese Journal of Cancer Research, April 16, 2013 Free full text
10 Vimentin expression predicts the occurrence of metastases in non small cell lung carcinomas Lung Cancer, April 12, 2013
11 Effects of erlotinib first-line maintenance therapy versus placebo on the health-related quality of life of patients with metastatic non-small-cell lung cancer European Journal of Cancer, March 18, 2013
12 A multicenter Phase II study of ganetespib monotherapy in patients with genotypically-defined advanced non-small cell lung cancer Clinical Cancer Research, April 9, 2013
13 Novel therapeutic targets in non-small cell lung cancer Current Opinion in Pharmacology , April 29, 2013 Review Article
14 Prospective, multicenter, randomized, independent-group, open-label phase II study to investigate the efficacy and safety of three regimens with two doses of sagopilone as second-line therapy in patients with stage IIIB or IV non-small-cell lung cancer Lung Cancer, April 2, 2013
15 Treatment of stage IIIb/IV non-small cell lung cancer with Pemetrexed plus Oxaliplatin after failure of Erlotinib as second-line treatment Medical Oncology, April 15, 2013
16 The use of fused PET/CT images for patient selection and radical radiotherapy target volume definition in patients with non-small cell lung cancer: Results of a prospective study with mature survival data Radiotherapy & Oncology, April 4, 2013
17 Randomized phase II study of ixabepilone or paclitaxel plus carboplatin in patients with non-small-cell lung cancer prospectively stratified by beta-3 tubulin status Journal of Clinical Oncology, April 25, 2013
18 Cruciferous vegetables consumption and the risk of female lung cancer: a prospective study and a meta-analysis Annals of Oncology, April 9, 2013 Review Article
19 The prognostic and predictive value of KRAS oncogene substitutions in lung adenocarcinoma Cancer, March 26, 2013
20 Mutation analysis of the EGFR gene and downstream signalling pathway in histologic samples of malignant pleural mesothelioma British Journal of Cancer, April 8, 2013
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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