Oncology - Leukemia/Lymphoma News & Articles

1 Phase 1 dose- escalation trial of clofarabine followed by escalating dose of fractionated cyclophosphamide in adults with relapsed or refractory acute leukaemias British Journal of Haematology, May 22, 2012

2 Therapy-related acute myeloid leukemia (t-AML) with poor-risk cytogenetics in two patients with persistent molecular complete remission of acute promyelocytic leukemia European Journal of Haematology, May 22, 2012

3 Isolated central nervous system relapses in primary mediastinal large B-cell lymphoma after CHOP-like chemotherapy with or without Rituximab Hematological Oncology, May 22, 2012    Clinical Article

4 SIL index including stage, soluble interleukin-2 receptor, and LDH is as a useful prognostic predictor in DLBCL Cancer Science, May 22, 2012    Clinical Article

5 Somatic STAT3 mutations in large granular lymphocytic leukemia New England Journal of Medicine, May 21, 2012

6 Over-expression of RPL23 in myelodysplastic syndromes is associated with apoptosis resistance of CD34+ cells and predicts poor prognosis and distinct response to CHG chemotherapy or decitabine Annals of Hematology, May 18, 2012

7 T315I Mutation in Ph-positive Acute Lymphoblastic Leukemia is Associated with a Highly Aggressive Disease Phenotype: Three Case Reports Anticancer Research, May 18, 2012

8 Carbonyl reductase 1 expression influences daunorubicin metabolism in acute myeloid leukemia European Journal of Clinical Pharmacology, May 18, 2012

9 Extended Use of Serum Free Light Chain as a Biomarker in Lymphoproliferative Disorders American Journal of Clinical Pathology, May 18, 2012

10 Early Lymphoid Development and Microenvironmental Cues in B-cell Acute Lymphoblastic Leukemia Archives of Medical Research, May 18, 2012

11 Lenalidomide maintenance after stem-cell transplantation for multiple myeloma New England Journal of Medicine, May 17, 2012    Clinical Article

12 Clofarabine plus cytarabine compared with cytarabine alone in older patients with relapsed or refractory acute myelogenous leukemia: results from the CLASSIC I trial Journal of Clinical Oncology, May 17, 2012    Clinical Article

13 Superiority of the triple combination of bortezomib-thalidomide-dexamethasone over the dual combination of thalidomide-dexamethasone in patients with multiple myeloma progressing or relapsing after autologous transplantation: The MMVAR/IFM 2005-04 randomized phase III trial from the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation Journal of Clinical Oncology, May 17, 2012    Clinical Article

14 Phase II trial of vorinostat with idarubicin and cytarabine for patients with newly diagnosed acute myelogenous leukemia or myelodysplastic syndrome Journal of Clinical Oncology, May 17, 2012    Clinical Article

15 Acute Myeloid Leukemia and Myelodysplastic Syndromes After Radiation Therapy Are Similar to De Novo Disease and Differ From Other Therapy-Related Myeloid Neoplasms Journal of Clinical Oncology, May 17, 2012

16 Development of a human monoclonal antibody for potential therapy of CD27-expressing lymphoma and leukemia Clinical Cancer Research, May 17, 2012

17 Standardized definitions of molecular response in chronic myeloid leukemia Leukemia, May 17, 2012

18 Pharmacokinetics of Dasatinib for Philadelphia- Positive Acute Lymphocytic Leukemia with Acquired T315I mutation Journal of Hematology & Oncology, May 17, 2012    Clinical Article

19 Lenalidomide after stem-cell transplantation for multiple myeloma New England Journal of Medicine, May 16, 2012    Clinical Article

20 Medical conditions and risk of adult myeloid leukemia Cancer Causes and Control, May 16, 2012

Stereotactic ablative radiotherapy for stage I NSCLC: Recent advances and controversies Journal of Thoracic Disease, 08/05/2011

1 Risk of lymphoma in women with breast implants: analysis of clinical studies European Journal of Cancer Prevention, April 6, 2012

2 Alemtuzumab in combination with methylprednisolone is a highly effective induction regimen for patients with chronic lymphocytic leukemia and deletion of TP53: Final results of the national cancer research institute Cll206 trial Journal of Clinical Oncology, April 12, 2012

3 Chemoimmunotherapy with ofatumumab in combination with CHOP in previously untreated follicular lymphoma British Journal of Haematology, April 2, 2012

4 Cladribine, But Not Fludarabine, Added to Daunorubicin and Cytarabine During Induction Prolongs Survival of Patients With Acute Myeloid Leukemia Journal of Clinical Oncology, April 19, 2012

5 Reduced-intensity chemotherapy and PET-guided radiotherapy in patients with advanced stage Hodgkin's lymphoma (HD15 trial): a randomised, open-label, phase 3 non-inferiority trial The Lancet - Early Online Publication, April 5, 2012

6 Effect of gemtuzumab ozogamicin on survival of adult patients with de-novo acute myeloid leukaemia (ALFA-0701): a randomised, open-label, phase 3 study The Lancet, April 24, 2012

7 Rituximab, gemcitabine, cisplatin, and dexamethasone in patients with refractory or relapsed aggressive B-cell lymphoma Medical Oncology, April 10, 2012

8 Prognostic impact of discordant results from cytogenetics and flow cytometry in patients with acute myeloid leukemia undergoing hematopoietic cell transplantation Cancer, April 17, 2012

9 Effect of gemtuzumab ozogamicin on survival of adult patients with de-novo acute myeloid leukaemia (ALFA-0701): a randomised, open-label, phase 3 study The Lancet - Early Online Publication, April 5, 2012

10 Incidence, risk factors and outcome of histological transformation in follicular lymphoma British Journal of Haematology, March 20, 2012

11 Prognostic index for acute- and lymphoma-type adult T-cell leukemia/lymphoma Journal of Clinical Oncology, April 9, 2012

12 How to manage acute promyelocytic leukemia Leukemia, April 4, 2012

13 Prognostic impact of extranodal involvement in diffuse large B-cell lymphoma in the rituximab era Cancer, April 26, 2012

14 Infectious complications of chemotherapy in clinically aggressive mature B and T cell lymphomas European Journal of Internal Medicine , April 3, 2012

15 Pesticide use, immunologic conditions, and risk of non-Hodgkin lymphoma in Canadian men in six provinces International Journal of Cancer, April 20, 2012

16 High Ki-67 expression in diffuse large B-cell lymphoma patients with non-germinal center subtype indicates limited survival benefit from R-CHOP therapy European Journal of Haematology, March 15, 2012

17 Ruxolitinib: The First FDA Approved Therapy for the Treatment of Myelofibrosis Clinical Cancer Research, April 4, 2012

18 High myc activity is an independent negative prognostic factor for diffuse large B cell lymphomas International Journal of Cancer, April 25, 2012

19 Molecular history of Richter syndrome: origin from a cell already present at the time of chronic lymphocytic leukemia diagnosis International Journal of Cancer, April 16, 2012

20 Results of a pivotal phase II study of brentuximab vedotin for patients with relapsed or refractory Hodgkins lymphoma Journal of Clinical Oncology, March 30, 2012