Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Oncology
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D Scott Cunningham MD, PhD
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121 The changing mutational landscape of acute myeloid leukemia and myelodysplastic syndrome Molecular Cancer Research, May 13, 2013 Review Article
122 High level of CD20 expression by flow cytometry predicts good prognosis in chronic lymphocytic leukemia Cancer Science, May 13, 2013 Clinical Article
123 Trends in utilization and survival after autologous hematopoietic cell transplantation in North America from 1995 to 2005: Significant improvement in survival for lymphoma and myeloma during a period of increasing recipient age Biology of Blood and Marrow Transplantation, May 13, 2013 Clinical Article
124 Protein-coding genes and long noncoding RNAs are differentially expressed in dasatinib-treated chronic myeloid leukemia patients with resistance to imatinib Hematology, May 13, 2013 Clinical Article
125 Extended lifespan of normal human B lymphocytes experimentally infected by SV40 or transfected by SV40 large T antigen expression vector Leukemia Research, May 13, 2013 Clinical Article
126 TCTP/HRF pathway and angiogenesis: A feasible intercourse in chronic lymphocytic leukemia Leukemia Research, May 13, 2013 Clinical Article
127 Absolute lymphocyte count is associated with minimal residual disease level in childhood B-cell precursor acute lymphoblastic leukemia Leukemia Research, May 13, 2013 Clinical Article
128 Tumor lysis syndrome soon after treatment with hydroxyurea followed by nilotinib in two patients with chronic-phase chronic myelogenous leukemia International Journal of Hematology, May 13, 2013 Clinical Article
129 Oncogenic CSF3R Mutations in Chronic Neutrophilic Leukemia and Atypical CML New England Journal of Medicine, May 13, 2013 Evidence Based Medicine Clinical Article
130 Homoharringtonine-based induction regimens for patients with de-novo acute myeloid leukaemia: a multicentre, open-label, randomised, controlled phase 3 trial The Lancet Oncology, May 10, 2013 Clinical Article
131 Breast cancer risk following Hodgkin lymphoma radiotherapy in relation to menstrual and reproductive factors British Journal of Cancer, May 10, 2013
132 Somatic hypermutation analysis in follicular lymphoma provides evidence suggesting bidirectional cell migration between lymph node and bone marrow during disease progression and relapse Full Text Haematologica, May 10, 2013 Clinical Article
133 Inactivation of PTEN increases ABCG2 expression and the side population through the PI3K/Akt pathway in adult acute leukemia Cancer Letters, May 10, 2013 Clinical Article
134 Determination of the molecular subtypes of diffuse large B-cell lymphomas using immunohistochemistry: a case series from the Inselspital, Bern, and a critical appraisal of this determination in Switzerland Full Text Swiss Medical Weekly, May 10, 2013
135 Igs Expressed by Chronic Lymphocytic Leukemia B Cells Show Limited Binding-Site Structure Variability The Journal of Immunology, May 10, 2013 Clinical Article
136 Azacitidine in the treatment of therapy related myelodysplastic syndrome and acute myeloid leukemia (tMDS/AML): A report on 54 patients by the Groupe Francophone Des Myelodysplasies (GFM) Leukemia Research, May 10, 2013 Clinical Article
137
Epstein-Barr Virus–Encoded miR-BART20-5p Inhibits T-bet Translation with Secondary Suppression of p53 in Invasive Nasal NK/T-Cell Lymphoma
American Journal of Pathology, May 10, 2013
Clinical Article
Exclusive Author Commentary
138 MYC status determination in aggressive B-cell lymphoma: the impact of FISH probe selection Histopathology, May 10, 2013 Clinical Article
139 Multicenter phase II study of bendamustine plus rituximab in patients with relapsed or refractory diffuse large B-cell lymphoma Journal of Clinical Oncology, May 9, 2013 Clinical Article
140 Genetic mediators of neurocognitive outcomes in survivors of childhood acute lymphoblastic leukemia Journal of Clinical Oncology, May 9, 2013
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 R-CVP versus R-CHOP versus R-FM for the initial treatment of patients with advanced-stage follicular lymphoma: Results of the FOLL05 Trial conducted by the Fondazione Italiana Linfomi Journal of Clinical Oncology, April 1, 2013
2 Management of Newly Diagnosed Symptomatic Multiple Myeloma: Updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) Consensus Guidelines 2013 Mayo Clinic Proceedings, April 2, 2013 Clinical Guideline
3 Intensive chemotherapy and immunotherapy in patients with newly diagnosed primary CNS lymphoma: CALGB 50202 (Alliance 50202) Journal of Clinical Oncology, April 15, 2013
4 The use of FDG-PET in the initial staging of 142 patients with follicular lymphoma: a retrospective study from the FOLL05 randomized trial of the Fondazione Italiana Linfomi Annals of Oncology, April 19, 2013
5 The role of maintenance therapy in acute promyelocytic leukemia in the first complete remission Cochrane Reviews, April 3, 2013 Evidence Based Medicine
6
Dose-dense rituximab-CHOP compared with standard rituximab-CHOP in elderly patients with diffuse large B-cell lymphoma (the LNH03-6B study): a randomised phase 3 trial
The Lancet Oncology, April 12, 2013
Exclusive Author Commentary
7 Rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisolone in patients with newly diagnosed diffuse large B-cell non-Hodgkin lymphoma: a phase 3 comparison of dose intensification with 14-day versus 21-day cycles The Lancet, April 23, 2013
8 90Yttrium-Ibritumomab Tiuxetan Consolidation of First Remission in Advanced-Stage Follicular Non-Hodgkin Lymphoma: Updated Results After a Median Follow-Up of 7.3 Years From the International, Randomized, Phase III First-Line Indolent Trial Journal of Clinical Oncology, April 4, 2013
9 Expression of CD133 in acute leukemia Medical Oncology, April 2, 2013
10 The changing paradigm of CLL management European Journal of Internal Medicine , April 17, 2013 Review Article
11 Leukaemia update. Part 1: diagnosis and management British Medical Journal, April 9, 2013 Review Article
12 Alcohol consumption and risk of lymphoid and myeloid neoplasms: Results of the Netherlands cohort study International Journal of Cancer, April 4, 2013
13 Curability of patients with acute myeloid leukemia who did not undergo transplantation in first remission Journal of Clinical Oncology, March 4, 2013
14 Peripheral artery occlusive disease in chronic phase chronic myeloid leukemia patients treated with nilotinib or imatinib Leukemia, April 11, 2013
15 Bendamustine compared to fludarabine as second-line treatment in chronic lymphocytic leukemia Annals of Hematology, April 9, 2013
16 Azacitidine might be beneficial in a subgroup of older AML patients compared to intensive chemotherapy: a single centre retrospective study of 227 consecutive patients Journal of Hematology & Oncology, April 18, 2013 Free full text
17 Safety and activity of crizotinib for paediatric patients with refractory solid tumours or anaplastic large-cell lymphoma: a Childrens Oncology Group phase 1 consortium study The Lancet Oncology, April 24, 2013
18 Prospective phase ii study on 5-days azacitidine (5d-aza) for treatment of symptomatic and/or erythropoietin unresponsive patients with low/int-1 risk myelodysplastic syndromes. Clinical Cancer Research, April 19, 2013
19 An antiapoptotic Bcl-2 family protein index predicts the response of leukaemic cells to the pan-Bcl-2 inhibitor S1 British Journal of Cancer, April 10, 2013
20 Salvage therapy using FLT3 inhibitors may improve long-term outcome of relapsed or refractory AML in patients with FLT3-ITD British Journal of Haematology, April 1, 2013
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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