Oncology - Leukemia/Lymphoma News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (11) Full Text Articles (948) Focus on Lung

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

21 Japonicone a suppresses growth of Burkitt lymphoma cells through its effect on NF-kappaB Clinical Cancer Research, May 15, 2013

22 Newly diagnosed adult AML and MPAL patients frequently show clonal residual hematopoiesis Leukemia, May 15, 2013 Clinical Article

23 Clonal Evolution, Genomic Drivers, and Effects of Therapy in Chronic Lymphocytic Leukemia Clinical Cancer Research, May 15, 2013 Clinical Article

24 6-Formylindolo (3,2-b)carbazole (FICZ) enhances retinoic acid (RA)-induced differentiation of HL-60 myeloblastic leukemia cells Full Text Molecular Cancer, May 15, 2013 Clinical Article

25 Lipoprotein lipase in chronic lymphocytic leukaemia - Strong biomarker with lack of functional significance Leukemia Research, May 15, 2013 Clinical Article

26 Sensitivity and resistance of JAK2 inhibitors to myeloproliferative neoplasms International Journal of Hematology, May 15, 2013 Clinical Article

27 Development of IgG4-related disease 10 years after chemotherapy for diffuse large B cell lymphoma and longstanding bronchial asthma International Journal of Hematology, May 15, 2013 Clinical Article

28 Mechanisms of action and resistance to all-trans retinoic acid (ATRA) and arsenic trioxide (As2O3) in acute promyelocytic leukemia International Journal of Hematology, May 15, 2013 Clinical Article

29 Thiopurine methyltransferase genotyping in Palestinian childhood acute lymphoblastic leukemia patients Full Text BMC Hematology, May 15, 2013 Clinical Article

30 Peripheral T-cell Lymphomas of Follicular T-Helper Cell Derivation With Hodgkin/Reed-Sternberg Cells of B-cell Lineage: Both EBV-positive and EBV-negative Variants Exist American Journal of Surgical Pathology , May 15, 2013 Clinical Article

31 A phase I, open-label study of siltuximab, an anti-IL-6 monoclonal antibody, in patients with B-cell non-Hodgkin's lymphoma, multiple myeloma, or Castleman's disease Clinical Cancer Research, May 14, 2013

32 The genomic landscape of chronic lymphocytic leukemia: clinical implications Full Text BMC Medicine, May 14, 2013

33 Targeting the CD20 and CXCR4 Pathways in Non Hodgkin Lymphoma with Rituximab and high affinity CXCR4 antagonist BKT140 Clinical Cancer Research, May 14, 2013 Clinical Article

34 Analyzing acute leukemia patients with complex MLL rearrangements by a sequential LDI-PCR approach Cancer Letters, May 14, 2013 Clinical Article

35 Targeting IL-15 in large granular lymphocyte leukemia Expert Review of Clinical Immunology, May 14, 2013 Review Article

36 Impact of serum adiponectin and leptin levels in acute leukemia Hematology, May 14, 2013 Clinical Article

37 The evaluation of protein Z levels of children with acute lymphoblastic leukaemia during induction therapy Blood Coagulation & Fibrinolysis, May 14, 2013 Clinical Article

38 Targeting FoxM1 Effectively Retards p53-Null Lymphoma and Sarcoma Molecular Cancer Therapeutics, May 14, 2013 Clinical Article

39 Transforming growth factor β signaling in myeloid cells is required for tumor metastasis Cancer Discovery, May 14, 2013 Clinical Article

40 Hydroa vacciniforme-like lymphoma of an adult: a case report with review of the literature Full Text Diagnostic Pathology, May 14, 2013

50 available pages First Previous 2 3 4 5 6 7 8 9 10 11 Next Last

Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 R-CVP versus R-CHOP versus R-FM for the initial treatment of patients with advanced-stage follicular lymphoma: Results of the FOLL05 Trial conducted by the Fondazione Italiana Linfomi Journal of Clinical Oncology, April 1, 2013

2 Management of Newly Diagnosed Symptomatic Multiple Myeloma: Updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) Consensus Guidelines 2013 Mayo Clinic Proceedings, April 2, 2013 Clinical Guideline

3 Intensive chemotherapy and immunotherapy in patients with newly diagnosed primary CNS lymphoma: CALGB 50202 (Alliance 50202) Journal of Clinical Oncology, April 15, 2013

4 The use of FDG-PET in the initial staging of 142 patients with follicular lymphoma: a retrospective study from the FOLL05 randomized trial of the Fondazione Italiana Linfomi Annals of Oncology, April 19, 2013

5 The role of maintenance therapy in acute promyelocytic leukemia in the first complete remission Cochrane Reviews, April 3, 2013 Evidence Based Medicine

6 Dose-dense rituximab-CHOP compared with standard rituximab-CHOP in elderly patients with diffuse large B-cell lymphoma (the LNH03-6B study): a randomised phase 3 trial The Lancet Oncology, April 12, 2013
Exclusive Author Commentary

7 Rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisolone in patients with newly diagnosed diffuse large B-cell non-Hodgkin lymphoma: a phase 3 comparison of dose intensification with 14-day versus 21-day cycles The Lancet, April 23, 2013

8 90Yttrium-Ibritumomab Tiuxetan Consolidation of First Remission in Advanced-Stage Follicular Non-Hodgkin Lymphoma: Updated Results After a Median Follow-Up of 7.3 Years From the International, Randomized, Phase III First-Line Indolent Trial Journal of Clinical Oncology, April 4, 2013

9 Expression of CD133 in acute leukemia Medical Oncology, April 2, 2013

10 The changing paradigm of CLL management European Journal of Internal Medicine , April 17, 2013 Review Article

11 Leukaemia update. Part 1: diagnosis and management British Medical Journal, April 9, 2013 Review Article

12 Alcohol consumption and risk of lymphoid and myeloid neoplasms: Results of the Netherlands cohort study International Journal of Cancer, April 4, 2013

13 Curability of patients with acute myeloid leukemia who did not undergo transplantation in first remission Journal of Clinical Oncology, March 4, 2013

14 Peripheral artery occlusive disease in chronic phase chronic myeloid leukemia patients treated with nilotinib or imatinib Leukemia, April 11, 2013

15 Bendamustine compared to fludarabine as second-line treatment in chronic lymphocytic leukemia Annals of Hematology, April 9, 2013

16 Azacitidine might be beneficial in a subgroup of older AML patients compared to intensive chemotherapy: a single centre retrospective study of 227 consecutive patients Journal of Hematology & Oncology, April 18, 2013 Free full text

17 Safety and activity of crizotinib for paediatric patients with refractory solid tumours or anaplastic large-cell lymphoma: a Childrens Oncology Group phase 1 consortium study The Lancet Oncology, April 24, 2013

18 Prospective phase ii study on 5-days azacitidine (5d-aza) for treatment of symptomatic and/or erythropoietin unresponsive patients with low/int-1 risk myelodysplastic syndromes. Clinical Cancer Research, April 19, 2013

19 An antiapoptotic Bcl-2 family protein index predicts the response of leukaemic cells to the pan-Bcl-2 inhibitor S1 British Journal of Cancer, April 10, 2013

20 Salvage therapy using FLT3 inhibitors may improve long-term outcome of relapsed or refractory AML in patients with FLT3-ITD British Journal of Haematology, April 1, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more

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Oncology - Leukemia/Lymphoma News & Articles

Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology