Oncology - Hepatobiliary/Pancreas News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (4) Full Text Articles (216) Focus on Pediatric

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

1 Mutant TP53 in duodenal samples of pancreatic juice from patients with pancreatic cancer or high-grade dysplasia Clinical Gastroenterology and Hepatology , May 22, 2013 Review Article

2 Cardiovascular Toxicity and Sorafenib: A Case Report American Journal of Therapeutics, May 22, 2013

3 High expression of cancer stem cell markers in cholangiolocellular carcinoma Surgery Today, May 22, 2013 Clinical Article

4 Outcome comparisons among the hangzhou, chengdu, and ucsf criteria for hepatocellular carcinoma liver transplantation after successful downstaging therapies Journal of Gastrointestinal Surgery, May 22, 2013 Clinical Article

Prior Articles

5 DLC-1 is a candidate biomarker methylated and down-regulated in pancreatic ductal adenocarcinoma Tumor Biology, May 21, 2013 Clinical Article

6 Hepatocellular carcinoma and focal nodular hyperplasia of the liver: differentiation with CT spectral imaging European Radiology, May 21, 2013 Clinical Article

7 Primary solid pancreatic tumors: recent imaging findings updates with pathology correlation Abdominal Imaging , May 21, 2013 Clinical Article

8 Targeting the Ras–ERK pathway in pancreatic adenocarcinoma Cancer and Metastasis Reviews, May 21, 2013 Review Article

9 Comparison of WHO Classifications (2004, 2010), the Hochwald Grading System, and AJCC and ENETS Staging Systems in Predicting Prognosis in Locoregional Well-differentiated Pancreatic Neuroendocrine Tumors American Journal of Surgical Pathology , May 21, 2013 Review Article

10 Circulating tumor cells in locally advanced pancreatic adenocarcinoma: the ancillary CirCe 07 study to the LAP 07 trial Annals of Oncology, May 20, 2013

11 Prevalence and risk factors of extrapancreatic malignancies in a large cohort of patients with intraductal papillary mucinous neoplasm (IPMN) of the pancreas Annals of Oncology, May 20, 2013 Clinical Article

12 Survival Is Associated With Genetic Variation in Inflammatory Pathway Genes Among Patients With Resected and Unresected Pancreatic Cancer Annals of Surgery, May 20, 2013 Clinical Article

13 A prospective analysis of telomere length and pancreatic cancer in the Alpha-Tocopherol Beta-Carotene Cancer Prevention (ATBC) Study International Journal of Cancer, May 17, 2013

14 Pharmacokinetic interaction between sorafenib and prednisolone in a patient with hepatocellular carcinoma Cancer Chemotherapy and Pharmacology, May 17, 2013

15 SALL-4 is a marker of embryonal subtype of hepatoblastoma Histopathology, May 17, 2013 Clinical Article

16 Immunohistochemical analysis of E-cadherin and zeste homolog 2 expression in endoscopic ultrasound-guided fine-needle aspiration of pancreatic adenocarcinoma Cancer Cytopathology, May 17, 2013 Clinical Article

17 Recurrence of hepatocellular carcinoma presenting as an asymptomatic appendiceal tumor: report of a case Surgery Today, May 17, 2013

18 Second-line treatment in advanced pancreatic cancer: a comprehensive analysis of published clinical trials Annals of Oncology, May 16, 2013 Clinical Article

19 Consumption of fish and meats and risk of hepatocellular carcinoma: the European Prospective Investigation into Cancer and Nutrition (EPIC) Annals of Oncology, May 16, 2013

20 Expression of metallothionein-1 and metallothionein-2 as a prognostic marker in hepatocellular carcinoma Journal of Gastroenterology and Hepatology, May 16, 2013 Review Article

50 available pages FirstPrevious 1 2 3 4 5 6 7 8 9 10 Next Last

Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 Gemcitabine-based or capecitabine-based chemoradiotherapy for locally advanced pancreatic cancer (SCALOP): a multicentre, randomised, phase 2 trial The Lancet Oncology, March 8, 2013

2 A Novel Serum Metabolomics-Based Diagnostic Approach to Pancreatic Cancer Cancer Epidemiology, Biomarkers & Prevention, April 2, 2013 Review Article

3 Cytokeratin 19-fragments (CYFRA 21-1) as a novel serum biomarker for response and survival in patients with advanced pancreatic cancer British Journal of Cancer, April 16, 2013

4 Response of liver metastases to preoperative radiochemotherapy in patients with locally advanced rectal cancer and resectable synchronous liver metastases Surgery, April 24, 2013

5 Randomized controlled trial of cetuximab plus chemotherapy for patients with KRAS wild-type unresectable colorectal liver-limited metastases Journal of Clinical Oncology, April 15, 2013

6 Inflammatory plasma markers and pancreatic cancer risk Cancer Epidemiology, Biomarkers & Prevention, April 17, 2013

7 Association of metformin use with cancer incidence and mortality: A meta-analysis Cancer Epidemiology, April 22, 2013 Review Article

8 Serum levels of IL-6 and IL-1beta can predict the efficacy of gemcitabine in patients with advanced pancreatic cancer British Journal of Cancer, April 24, 2013

9 Pirfenidone Inhibits Desmoplasia of Pancreatic Cancer Cancer Research, April 1, 2013

10 Biliary Findings Assist in Predicting Enlargement of Intraductal Papillary Mucinous Neoplasms of the Pancreas Clinical Gastroenterology and Hepatology , April 25, 2013

11 Safety and efficacy of adjuvant pegylated interferon therapy for metastatic tumor antigen 1-positive hepatocellular carcinoma Cancer, April 10, 2013

12 Phase I Study of Rigosertib, an Inhibitor of the Phosphatidylinositol 3-Kinase and Polo-like Kinase 1 Pathways, Combined with Gemcitabine in Patients with Solid Tumors and Pancreatic Cancer Clinical Cancer Research, March 26, 2012 Free full text

13 Evaluation of risk factors for extrahepatic cholangiocarcinoma: ABO blood group, hepatitis B virus, and their synergism International Journal of Cancer, April 11, 2013

14 Neoadjuvant FOLFIRI+bevacizumab in patients with resectable liver metastases from colorectal cancer: a phase 2 trial British Journal of Cancer, April 9, 2013

15 Sorafenib combined with transarterial chemoembolization for the treatment of advanced hepatocellular carcinoma: a large-scale multicenter study of 222 patients Annals of Oncology, March 21, 2013

16 Gemcitabine plus Nab-Paclitaxel with chemoradiation in locally advanced pancreatic cancer (LAPC) Journal of Gastrointestinal Oncology, April 23, 2013 Free full text

17 Identification and impact of hepatitis B virus DNA and antigens in pancreatic cancer tissues and adjacent non-cancerous tissues Cancer Letters, April 3, 2013

18 Usefulness of MALDI-TOF/MS Identification of Low-MW Fragments in Sera for the Differential Diagnosis of Pancreatic Cancer Pancreas, April 25, 2013 Review Article

19 Endoscopic snare papillectomy: a possible radical treatment for a subgroup of T1 ampullary adenocarcinomas Endoscopy, April 26, 2013 Review Article

20 Short term chemotherapy followed by radiofrequency ablation in stage III pancreatic cancer: results from a single center Journal of Hepato-Biliary-Pancreatic Sciences, April 26, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more

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Oncology - Hepatobiliary/Pancreas News & Articles

Articles

Prior Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology