Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Oncology
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D Scott Cunningham MD, PhD
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101 Clinical importance of Familial Pancreatic Cancer Registry in Japan: a report from kick-off meeting at International Symposium on Pancreas Cancer 2012 Journal of Hepato-Biliary-Pancreatic Sciences, May 1, 2013 Review Article
102 Roles for KRAS in Pancreatic Tumor Development and Progression Gastroenterology, April 30, 2013 Review Article
103 Role of Immune Cells and Immune-Based Therapies in Pancreatitis and Pancreatic Ductal Adenocarcinoma Gastroenterology, April 30, 2013 Review Article
104
Photodynamic therapy for human hepatoma-cell–line tumors utilizing biliary excretion properties of indocyanine green
Journal of Gastroenterology, April 30, 2013
Clinical Article
Exclusive Author Commentary
105 Clinicopathological significance of S100 protein expression in cholangiocarcinoma Journal of Gastroenterology and Hepatology, April 30, 2013 Review Article
106 Pseudogene OCT4-pg4 functions as a natural microRNA sponge to regulate OCT4 expression by competing for miR-145 in hepatocellular carcinoma Carcinogenesis, April 30, 2013 Clinical Article
107 Increased international normalized ratio level in hepatocellular carcinoma patients with diabetes mellitus Full Text World Journal of Gastroenterology, April 30, 2013 Review Article
108 Expression and clinical significance of apolipoprotein E in pancreatic ductal adenocarcinoma Medical Oncology, April 29, 2013 Clinical Article
109 Enhancer of Zeste Homolog 2 Silences MicroRNA-218 in Human Pancreatic Ductal Adenocarcinoma Cells by Inducing Formation of Heterochromatin Gastroenterology, April 29, 2013 Review Article
110 Pathological diagnosis of flat epithelial lesions of the biliary tract with emphasis on biliary intraepithelial neoplasia Journal of Gastroenterology, April 29, 2013 Review Article
111 Risk for Mortality From Causes Other Than Pancreatic Cancer in Patients With Intraductal Papillary Mucinous Neoplasm of the Pancreas Pancreas, April 29, 2013 Clinical Article
112 HBx-mediated miR-21 upregulation represses tumor-suppressor function of PDCD4 in hepatocellular carcinoma Oncogene, April 29, 2013 Clinical Article
113 An unusual gallbladder carcinoma with tumor thrombus in the common bile duct Journal of Cancer Research and Therapeutics, April 29, 2013
114 Glypican-3 is a potential prognostic biomarker for hepatocellular carcinoma after curative resection Surgery, April 29, 2013 Clinical Article
115 Laparoscopic Ultrasound for Hepatocellular Carcinoma and Colorectal Liver Metastasis: An Overview Surgical Laparoscopy, Endoscopy & Percutaneous Techniques, April 29, 2013 Review Article
116 Multivariate Analysis of Prognostic Factors for Survival following Doxorubicin-eluting Bead Transarterial Chemoembolization for Hepatocellular Carcinoma Journal of Vascular and Interventional Radiology, April 29, 2013 Clinical Article
117 Spontaneous rupture of an advanced pancreatoblastoma: Aberrant RASSF1A methylation and CTNNB1 mutation as molecular genetic markers Journal of Pediatric Surgery, April 29, 2013
118 Endoscopic snare papillectomy: a possible radical treatment for a subgroup of T1 ampullary adenocarcinomas Endoscopy, April 26, 2013 Review Article
119 Ultrasound-guided vs endoscopic ultrasound-guided fine-needle aspiration for pancreatic cancer diagnosis Full Text World Journal of Gastroenterology, April 26, 2013 Clinical Article
120 TL-118--anti-angiogenic treatment in pancreatic cancer: a case report Medical Oncology, April 26, 2013
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 Gemcitabine-based or capecitabine-based chemoradiotherapy for locally advanced pancreatic cancer (SCALOP): a multicentre, randomised, phase 2 trial The Lancet Oncology, March 8, 2013
2 A Novel Serum Metabolomics-Based Diagnostic Approach to Pancreatic Cancer Cancer Epidemiology, Biomarkers & Prevention, April 2, 2013 Review Article
3 Cytokeratin 19-fragments (CYFRA 21-1) as a novel serum biomarker for response and survival in patients with advanced pancreatic cancer British Journal of Cancer, April 16, 2013
4 Response of liver metastases to preoperative radiochemotherapy in patients with locally advanced rectal cancer and resectable synchronous liver metastases Surgery, April 24, 2013
5 Randomized controlled trial of cetuximab plus chemotherapy for patients with KRAS wild-type unresectable colorectal liver-limited metastases Journal of Clinical Oncology, April 15, 2013
6 Inflammatory plasma markers and pancreatic cancer risk Cancer Epidemiology, Biomarkers & Prevention, April 17, 2013
7 Association of metformin use with cancer incidence and mortality: A meta-analysis Cancer Epidemiology, April 22, 2013 Review Article
8 Serum levels of IL-6 and IL-1beta can predict the efficacy of gemcitabine in patients with advanced pancreatic cancer British Journal of Cancer, April 24, 2013
9 Pirfenidone Inhibits Desmoplasia of Pancreatic Cancer Cancer Research, April 1, 2013
10 Biliary Findings Assist in Predicting Enlargement of Intraductal Papillary Mucinous Neoplasms of the Pancreas Clinical Gastroenterology and Hepatology , April 25, 2013
11 Safety and efficacy of adjuvant pegylated interferon therapy for metastatic tumor antigen 1-positive hepatocellular carcinoma Cancer, April 10, 2013
12 Phase I Study of Rigosertib, an Inhibitor of the Phosphatidylinositol 3-Kinase and Polo-like Kinase 1 Pathways, Combined with Gemcitabine in Patients with Solid Tumors and Pancreatic Cancer Clinical Cancer Research, March 26, 2012 Free full text
13 Evaluation of risk factors for extrahepatic cholangiocarcinoma: ABO blood group, hepatitis B virus, and their synergism International Journal of Cancer, April 11, 2013
14 Neoadjuvant FOLFIRI+bevacizumab in patients with resectable liver metastases from colorectal cancer: a phase 2 trial British Journal of Cancer, April 9, 2013
15 Sorafenib combined with transarterial chemoembolization for the treatment of advanced hepatocellular carcinoma: a large-scale multicenter study of 222 patients Annals of Oncology, March 21, 2013
16 Gemcitabine plus Nab-Paclitaxel with chemoradiation in locally advanced pancreatic cancer (LAPC) Journal of Gastrointestinal Oncology, April 23, 2013 Free full text
17 Identification and impact of hepatitis B virus DNA and antigens in pancreatic cancer tissues and adjacent non-cancerous tissues Cancer Letters, April 3, 2013
18 Usefulness of MALDI-TOF/MS Identification of Low-MW Fragments in Sera for the Differential Diagnosis of Pancreatic Cancer Pancreas, April 25, 2013 Review Article
19 Endoscopic snare papillectomy: a possible radical treatment for a subgroup of T1 ampullary adenocarcinomas Endoscopy, April 26, 2013 Review Article
20 Short term chemotherapy followed by radiofrequency ablation in stage III pancreatic cancer: results from a single center Journal of Hepato-Biliary-Pancreatic Sciences, April 26, 2013
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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