Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Oncology
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D Scott Cunningham MD, PhD
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Markers of obesity and inflammation in postmenopausal breast cancer
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Running from that pile of unread journals?
981 Clinical implications of biological markers in pancreatic ductal adenocarcinoma Surgical Oncology, October 22, 2012
982 Laparoscopic Anatomic Monosegmentectomy of Hepatocellular Carcinoma of the Right Hepatic Lobe Surgical Laparoscopy, Endoscopy & Percutaneous Techniques, October 19, 2012 Clinical Article
983 The Improvement of Surgical Treatment for Patients with Gallbladder Cancer: Analysis of 208 Consecutive Cases Over the Past Decade Journal of Gastrointestinal Surgery, October 19, 2012
984 Diagnostic utility of von Hippel-Lindau gene product, maspin, IMP3, and S100P in adenocarcinoma of the gallbladder Human Pathology, October 19, 2012
985 Risk of peritoneal carcinomatosis by endoscopic ultrasound-guided fine needle aspiration for pancreatic cancer Journal of Gastroenterology, October 19, 2012
986 Atypical hepatocellular adenoma-like neoplasms with β-catenin activation show cytogenetic alterations similar to well-differentiated hepatocellular carcinomas Human Pathology, October 19, 2012
987 Surgical strategy for patients with pancreatic body/tail carcinoma: Who should undergo distal pancreatectomy with en-bloc celiac axis resection Surgery, October 19, 2012
988 Feasibility of gemcitabine plus oxaliplatin in advanced hepatocellular carcinoma patients with Child-Pugh B cirrhosis Oncology, October 18, 2012
989 Radioembolisation with Yttrium-90 microspheres: An effective treatment modality for unresectable liver metastases Journal of Medical Imaging and Radiation Oncology, October 18, 2012
990 Outcomes of laparoscopic and open resection for neuroendocrine liver metastases Surgery, October 18, 2012 Clinical Article
991 Overexpression of ecdysoneless in pancreatic cancer and its role in oncogenesis by regulating glycolysis Clinical Cancer Research, October 17, 2012
992 Assessment of Preoperative Magnetic Resonance Imaging Staging in Patients With Hepatocellular Carcinoma Undergoing Resection Compared With the Seventh American Joint Committee on Cancer System Investigative Radiology, October 17, 2012 Clinical Article
993 Down-regulation of Toll-like receptor 7 expression in hepatitis-virus-related human hepatocellular carcinoma Human Pathology, October 17, 2012
994 Reclassification of tumour origin in resected periampullary adenocarcinomas reveals underestimation of distal bile duct cancer European Journal of Surgical Oncology, October 17, 2012
995 Intrahepatic Biliary Intraductal Papillary Mucinous Neoplasm With Gallbladder Agenesis: Case Report Surgical Laparoscopy, Endoscopy & Percutaneous Techniques, October 17, 2012
996 The cellular level of histone H3 lysine 4 dimethylation correlates with response to adjuvant gemcitabine in Japanese pancreatic cancer patients treated with surgery European Journal of Surgical Oncology, October 16, 2012 Clinical Article
997 Tissue Tolerable Plasma (TTP) induces apoptosis in pancreatic cancer cells in vitro and in vivo. Full Text BMC Cancer, October 16, 2012
998 Inflammatory gene variants and the risk of biliary tract cancers and stones: a population-based study in China Full Text BMC Cancer, October 15, 2012
999 Interference with ATF5 Function Enhances the Sensitivity of Human Pancreatic Cancer Cells to Paclitaxel-induced Apoptosis Anticancer Research, October 15, 2012
1000 The similarity of Type 1 autoimmune pancreatitis to pancreatic ductal adenocarcinoma with significant IgG4-positive plasma cell infiltration Journal of Gastroenterology, October 15, 2012
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 Gemcitabine-based or capecitabine-based chemoradiotherapy for locally advanced pancreatic cancer (SCALOP): a multicentre, randomised, phase 2 trial The Lancet Oncology, March 8, 2013
2 A Novel Serum Metabolomics-Based Diagnostic Approach to Pancreatic Cancer Cancer Epidemiology, Biomarkers & Prevention, April 2, 2013 Review Article
3 Cytokeratin 19-fragments (CYFRA 21-1) as a novel serum biomarker for response and survival in patients with advanced pancreatic cancer British Journal of Cancer, April 16, 2013
4 Response of liver metastases to preoperative radiochemotherapy in patients with locally advanced rectal cancer and resectable synchronous liver metastases Surgery, April 24, 2013
5 Randomized controlled trial of cetuximab plus chemotherapy for patients with KRAS wild-type unresectable colorectal liver-limited metastases Journal of Clinical Oncology, April 15, 2013
6 Inflammatory plasma markers and pancreatic cancer risk Cancer Epidemiology, Biomarkers & Prevention, April 17, 2013
7 Association of metformin use with cancer incidence and mortality: A meta-analysis Cancer Epidemiology, April 22, 2013 Review Article
8 Serum levels of IL-6 and IL-1beta can predict the efficacy of gemcitabine in patients with advanced pancreatic cancer British Journal of Cancer, April 24, 2013
9 Pirfenidone Inhibits Desmoplasia of Pancreatic Cancer Cancer Research, April 1, 2013
10 Biliary Findings Assist in Predicting Enlargement of Intraductal Papillary Mucinous Neoplasms of the Pancreas Clinical Gastroenterology and Hepatology , April 25, 2013
11 Safety and efficacy of adjuvant pegylated interferon therapy for metastatic tumor antigen 1-positive hepatocellular carcinoma Cancer, April 10, 2013
12 Phase I Study of Rigosertib, an Inhibitor of the Phosphatidylinositol 3-Kinase and Polo-like Kinase 1 Pathways, Combined with Gemcitabine in Patients with Solid Tumors and Pancreatic Cancer Clinical Cancer Research, March 26, 2012 Free full text
13 Evaluation of risk factors for extrahepatic cholangiocarcinoma: ABO blood group, hepatitis B virus, and their synergism International Journal of Cancer, April 11, 2013
14 Neoadjuvant FOLFIRI+bevacizumab in patients with resectable liver metastases from colorectal cancer: a phase 2 trial British Journal of Cancer, April 9, 2013
15 Sorafenib combined with transarterial chemoembolization for the treatment of advanced hepatocellular carcinoma: a large-scale multicenter study of 222 patients Annals of Oncology, March 21, 2013
16 Gemcitabine plus Nab-Paclitaxel with chemoradiation in locally advanced pancreatic cancer (LAPC) Journal of Gastrointestinal Oncology, April 23, 2013 Free full text
17 Identification and impact of hepatitis B virus DNA and antigens in pancreatic cancer tissues and adjacent non-cancerous tissues Cancer Letters, April 3, 2013
18 Usefulness of MALDI-TOF/MS Identification of Low-MW Fragments in Sera for the Differential Diagnosis of Pancreatic Cancer Pancreas, April 25, 2013 Review Article
19 Endoscopic snare papillectomy: a possible radical treatment for a subgroup of T1 ampullary adenocarcinomas Endoscopy, April 26, 2013 Review Article
20 Short term chemotherapy followed by radiofrequency ablation in stage III pancreatic cancer: results from a single center Journal of Hepato-Biliary-Pancreatic Sciences, April 26, 2013
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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