Oncology - Hepatobiliary/Pancreas News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (13) Full Text Articles (216) Focus on Renal

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

81 Downregulated expression of hepatoma-derived growth factor (HDGF) reduces gallbladder cancer cell proliferation and invasion Medical Oncology, May 9, 2013 Clinical Article

82 Diabetes is not an independent risk factor for hepatocellular carcinoma Diabetes/Metabolism Research and Reviews, May 9, 2013 Review Article

83 Dietary flavonoid, lignan and antioxidant capacity and risk of hepatocellular carcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC) Study International Journal of Cancer, May 8, 2013

84 Pancreatic Cancer-Associated Stellate Cells Promote Differentiation of Myeloid-Derived Suppressor Cells in a STAT3-Dependent Manner Cancer Research, May 8, 2013 Clinical Article

85 Impact of Standardized Allergen-Removed Rhus verniciflua Stokes Extract on Advanced Adenocarcinoma of the Ampulla of Vater: A Case Series Full Text Evidence-based Complementary and Alternative Medicine , May 8, 2013 Clinical Article

86 Radiotherapy in the Management of Pancreatic Neuroendocrine Tumors (PNET): Experience at Three Institutions Anticancer Research, May 8, 2013 Clinical Article

87 Antiproliferative and Apoptosis-inducing Activity of Curcumin against Human Gallbladder Adenocarcinoma Cells Anticancer Research, May 8, 2013 Clinical Article

88 Postoperative peripheral blood monocyte count correlates with postoperative bile leakage in patients with colorectal liver metastases after hepatic resection Langenbeck's Archives of Surgery, May 8, 2013 Clinical Article

89 Fusion of intravenous contrast-enhanced C-arm CT and pretreatment imaging for ablation margin assessment of liver tumors: A preliminary study Full Text Indian Journal of Radiology and Imaging, May 8, 2013 Clinical Article

90 Selective doxorubicin drug eluting beads chemoembolization of hypovascular hepatocellular carcinoma using cone beam computed tomography Full Text Indian Journal of Radiology and Imaging, May 8, 2013 Clinical Article

91 Limited Efficacy of 18F-FDG PET/CT for Differentiation Between Metastasis-Free Pancreatic Cancer and Mass-Forming Pancreatitis Clinical Nuclear Medicine , May 8, 2013 Clinical Article

92 Inflammatory plasma markers and pancreatic cancer risk Cancer Epidemiology, Biomarkers & Prevention, May 7, 2013

93 The influence of adjuvant radiotherapy dose on overall survival in patients with resected pancreatic adenocarcinoma Cancer, May 7, 2013 Clinical Article

94 Hypoxia triggers Hedgehog-mediated tumor stromal interactions in pancreatic cancer Cancer Research, May 7, 2013 Clinical Article

95 A phase I study of IMP321 and gemcitabine as the front-line therapy in patients with advanced pancreatic adenocarcinoma Investigational New Drugs, May 7, 2013 Clinical Article

96 Relation Between Antibody to Hepatitis B Core Antigen and Survival after Curative Therapy for Non-B Non-C Hepatocellular Carcinoma Anticancer Research, May 7, 2013 Clinical Article

97 Ex vivo analysis of pancreatic cancer-infiltrating T lymphocytes reveals that ENO-specific Tregs accumulate in tumor tissue and inhibit Th1/Th17 effector cell functions Cancer Immunology, Immunotherapy, May 7, 2013 Clinical Article

98 Nr5a2 maintains acinar cell differentiation and constrains oncogenic Kras-mediated pancreatic neoplastic initiation Gut, May 7, 2013 Review Article

99 Liver resection in selected patients with metastatic breast cancer: a single-centre analysis and review of literature Journal of Cancer Research & Clinical Oncology, May 7, 2013 Review Article

100 Infiltration of peritumoural but tumour-free parenchyma with IgG4-positive plasma cells in hilar cholangiocarcinoma and pancreatic adenocarcinoma Digestive and Liver Diseases, May 7, 2013 Clinical Article

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Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 Gemcitabine-based or capecitabine-based chemoradiotherapy for locally advanced pancreatic cancer (SCALOP): a multicentre, randomised, phase 2 trial The Lancet Oncology, March 8, 2013

2 A Novel Serum Metabolomics-Based Diagnostic Approach to Pancreatic Cancer Cancer Epidemiology, Biomarkers & Prevention, April 2, 2013 Review Article

3 Cytokeratin 19-fragments (CYFRA 21-1) as a novel serum biomarker for response and survival in patients with advanced pancreatic cancer British Journal of Cancer, April 16, 2013

4 Response of liver metastases to preoperative radiochemotherapy in patients with locally advanced rectal cancer and resectable synchronous liver metastases Surgery, April 24, 2013

5 Randomized controlled trial of cetuximab plus chemotherapy for patients with KRAS wild-type unresectable colorectal liver-limited metastases Journal of Clinical Oncology, April 15, 2013

6 Inflammatory plasma markers and pancreatic cancer risk Cancer Epidemiology, Biomarkers & Prevention, April 17, 2013

7 Association of metformin use with cancer incidence and mortality: A meta-analysis Cancer Epidemiology, April 22, 2013 Review Article

8 Serum levels of IL-6 and IL-1beta can predict the efficacy of gemcitabine in patients with advanced pancreatic cancer British Journal of Cancer, April 24, 2013

9 Pirfenidone Inhibits Desmoplasia of Pancreatic Cancer Cancer Research, April 1, 2013

10 Biliary Findings Assist in Predicting Enlargement of Intraductal Papillary Mucinous Neoplasms of the Pancreas Clinical Gastroenterology and Hepatology , April 25, 2013

11 Safety and efficacy of adjuvant pegylated interferon therapy for metastatic tumor antigen 1-positive hepatocellular carcinoma Cancer, April 10, 2013

12 Phase I Study of Rigosertib, an Inhibitor of the Phosphatidylinositol 3-Kinase and Polo-like Kinase 1 Pathways, Combined with Gemcitabine in Patients with Solid Tumors and Pancreatic Cancer Clinical Cancer Research, March 26, 2012 Free full text

13 Evaluation of risk factors for extrahepatic cholangiocarcinoma: ABO blood group, hepatitis B virus, and their synergism International Journal of Cancer, April 11, 2013

14 Neoadjuvant FOLFIRI+bevacizumab in patients with resectable liver metastases from colorectal cancer: a phase 2 trial British Journal of Cancer, April 9, 2013

15 Sorafenib combined with transarterial chemoembolization for the treatment of advanced hepatocellular carcinoma: a large-scale multicenter study of 222 patients Annals of Oncology, March 21, 2013

16 Gemcitabine plus Nab-Paclitaxel with chemoradiation in locally advanced pancreatic cancer (LAPC) Journal of Gastrointestinal Oncology, April 23, 2013 Free full text

17 Identification and impact of hepatitis B virus DNA and antigens in pancreatic cancer tissues and adjacent non-cancerous tissues Cancer Letters, April 3, 2013

18 Usefulness of MALDI-TOF/MS Identification of Low-MW Fragments in Sera for the Differential Diagnosis of Pancreatic Cancer Pancreas, April 25, 2013 Review Article

19 Endoscopic snare papillectomy: a possible radical treatment for a subgroup of T1 ampullary adenocarcinomas Endoscopy, April 26, 2013 Review Article

20 Short term chemotherapy followed by radiofrequency ablation in stage III pancreatic cancer: results from a single center Journal of Hepato-Biliary-Pancreatic Sciences, April 26, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more

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Oncology - Hepatobiliary/Pancreas News & Articles

Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology