Oncology - Hepatobiliary/Pancreas News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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D Scott Cunningham MD, PhD
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Articles

Latest (13) Full Text Articles (216) Focus on Renal

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

61 Carcinosarcoma of the liver: report of a case Surgery Today, May 13, 2013 Review Article

62 Autoantibodies to MUC1 glycopeptides cannot be used as a screening assay for early detection of breast, ovarian, lung or pancreatic cancer British Journal of Cancer, May 10, 2013

63 Treatment outcome of advanced pancreatic cancer patients who are ineligible for a clinical trial Full Text OncoTargets and Therapy, May 10, 2013 Clinical Article

64 High Prevalence of BRCA1 and BRCA2 Germline Mutations With Loss of Heterozygosity In a Series of Resected Pancreatic Adenocarcinoma and Other Neoplastic Lesions Clinical Cancer Research, May 10, 2013 Clinical Article

65 Inflammatory Monocyte Mobilization Decreases Patient Survival in Pancreatic Cancer: a Role for Targeting the CCL2/CCR2 Axis Clinical Cancer Research, May 10, 2013 Clinical Article

66 ABO Blood Group and Risk of Pancreatic Cancer: A Study in Shanghai and Meta-Analysis American Journal of Epidemiology, May 10, 2013 Evidence Based Medicine Review Article

67 Chromophobe hepatocellular carcinoma with abrupt anaplasia: a proposal for a new subtype of hepatocellular carcinoma with unique morphological and molecular features Modern Pathology, May 10, 2013 Clinical Article

68 A treatment planning comparison of four target volume contouring guidelines for locally advanced pancreatic cancer radiotherapy Radiotherapy & Oncology, May 10, 2013 Clinical Guideline Clinical Article

69 Monitoring of Circulating Tumor Cells in Patients Undergoing Surgery for Hepatic Metastases from Colorectal Cancer Anticancer Research, May 10, 2013 Clinical Article

70 Development and preliminary validation of the pancreatic cancer disease impact score Supportive Care in Cancer, May 10, 2013 Clinical Article

71 TGF-β1 -509C/T (or +869T/C) polymorphism might be not associated with hepatocellular carcinoma risk Tumor Biology, May 10, 2013 Evidence Based Medicine Clinical Article

72 A comparison between intraductal papillary neoplasms of the biliary tract (BT-IPMNs) and intraductal papillary mucinous neoplasms of the pancreas (P-IPMNs) reveals distinct clinical manifestations and outcomes European Journal of Surgical Oncology, May 10, 2013 Clinical Article

73 Carcinoma of the gallbladder: Patterns of presentation, prognostic factors and survival rate. An 11-year single centre experience European Journal of Surgical Oncology, May 10, 2013 Review Article

74 Myeloid Differentiation Factor 88 Promotes Growth and Metastasis of Human Hepatocellular Carcinoma Clinical Cancer Research, May 10, 2013 Clinical Article

75 Analysis of the Efficacy of Portal Vein Embolization for Patients with Extensive Liver Malignancy and Very Low Future Liver Remnant Volume, Including a Comparison with the Associating Liver Partition with Portal Vein Ligation for Staged Hepatectomy Approach Journal of the American College of Surgeons, May 10, 2013 Clinical Article

76 Comparison of resection and transarterial chemoembolisation in the treatment of advanced intrahepatic cholangiocarcinoma - A single-center experience European Journal of Surgical Oncology, May 10, 2013 Clinical Article

77 Multidisciplinary management of hepatocellular carcinoma: a model for therapy Journal of Multidisciplinary Healthcare, May 10, 2013 Review Article

78 Association between tuberculosis infections and non-pulmonary malignancies: a nationwide population-based study British Journal of Cancer, May 9, 2013

79 Biology and Clinical Applications of Pancreatic Cancer Stem Cells Gastroenterology, May 9, 2013 Review Article

80 Transarterial Chemoembolization Using DEBIRI for Treatment of Hepatic Metastases from Colorectal Cancer Anticancer Research, May 9, 2013 Clinical Article

50 available pages First Previous 4 5 6 7 8 9 10 11 12 13 Next Last

Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 Gemcitabine-based or capecitabine-based chemoradiotherapy for locally advanced pancreatic cancer (SCALOP): a multicentre, randomised, phase 2 trial The Lancet Oncology, March 8, 2013

2 A Novel Serum Metabolomics-Based Diagnostic Approach to Pancreatic Cancer Cancer Epidemiology, Biomarkers & Prevention, April 2, 2013 Review Article

3 Cytokeratin 19-fragments (CYFRA 21-1) as a novel serum biomarker for response and survival in patients with advanced pancreatic cancer British Journal of Cancer, April 16, 2013

4 Response of liver metastases to preoperative radiochemotherapy in patients with locally advanced rectal cancer and resectable synchronous liver metastases Surgery, April 24, 2013

5 Randomized controlled trial of cetuximab plus chemotherapy for patients with KRAS wild-type unresectable colorectal liver-limited metastases Journal of Clinical Oncology, April 15, 2013

6 Inflammatory plasma markers and pancreatic cancer risk Cancer Epidemiology, Biomarkers & Prevention, April 17, 2013

7 Association of metformin use with cancer incidence and mortality: A meta-analysis Cancer Epidemiology, April 22, 2013 Review Article

8 Serum levels of IL-6 and IL-1beta can predict the efficacy of gemcitabine in patients with advanced pancreatic cancer British Journal of Cancer, April 24, 2013

9 Pirfenidone Inhibits Desmoplasia of Pancreatic Cancer Cancer Research, April 1, 2013

10 Biliary Findings Assist in Predicting Enlargement of Intraductal Papillary Mucinous Neoplasms of the Pancreas Clinical Gastroenterology and Hepatology , April 25, 2013

11 Safety and efficacy of adjuvant pegylated interferon therapy for metastatic tumor antigen 1-positive hepatocellular carcinoma Cancer, April 10, 2013

12 Phase I Study of Rigosertib, an Inhibitor of the Phosphatidylinositol 3-Kinase and Polo-like Kinase 1 Pathways, Combined with Gemcitabine in Patients with Solid Tumors and Pancreatic Cancer Clinical Cancer Research, March 26, 2012 Free full text

13 Evaluation of risk factors for extrahepatic cholangiocarcinoma: ABO blood group, hepatitis B virus, and their synergism International Journal of Cancer, April 11, 2013

14 Neoadjuvant FOLFIRI+bevacizumab in patients with resectable liver metastases from colorectal cancer: a phase 2 trial British Journal of Cancer, April 9, 2013

15 Sorafenib combined with transarterial chemoembolization for the treatment of advanced hepatocellular carcinoma: a large-scale multicenter study of 222 patients Annals of Oncology, March 21, 2013

16 Gemcitabine plus Nab-Paclitaxel with chemoradiation in locally advanced pancreatic cancer (LAPC) Journal of Gastrointestinal Oncology, April 23, 2013 Free full text

17 Identification and impact of hepatitis B virus DNA and antigens in pancreatic cancer tissues and adjacent non-cancerous tissues Cancer Letters, April 3, 2013

18 Usefulness of MALDI-TOF/MS Identification of Low-MW Fragments in Sera for the Differential Diagnosis of Pancreatic Cancer Pancreas, April 25, 2013 Review Article

19 Endoscopic snare papillectomy: a possible radical treatment for a subgroup of T1 ampullary adenocarcinomas Endoscopy, April 26, 2013 Review Article

20 Short term chemotherapy followed by radiofrequency ablation in stage III pancreatic cancer: results from a single center Journal of Hepato-Biliary-Pancreatic Sciences, April 26, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more

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Oncology - Hepatobiliary/Pancreas News & Articles

Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology