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Oncology - Head and Neck News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (12) Full Text Articles (176) Focus on Head & neck
Ranked, sorted, and summarized by MDLinx editors from the latest literature
Topics:

981 Tumour budding and the expression of cancer stem cell marker aldehyde dehydrogenase 1 in nasopharyngeal carcinoma Histopathology, December 4, 2012

982 Functional genetic variations in the IL-23 receptor gene are associated with risk of breast, lung and nasopharyngeal cancer in Chinese populations Carcinogenesis, December 4, 2012

983 Neuroendocrine differentiation in head and neck squamous cell carcinoma The Journal of Laryngology & Otology, December 4, 2012

984 External auditory canal paraganglioma: an atypical presentation The Journal of Laryngology & Otology, December 4, 2012

985 Human papillomavirus, smoking status and outcomes in tonsillar squamous cell carcinoma International Journal of Cancer, December 3, 2012

986 Novel diagnostic modalities for assessment of the clinically node-negative neck in oral squamous-cell carcinoma The Lancet Oncology, December 3, 2012

987 Diagnosis and treatment outcomes for patients with lymphoma of the parotid gland The Laryngoscope, December 3, 2012    Clinical Article

988 High expression levels of COX-2 and P300 are associated with unfavorable survival in laryngeal squamous cell carcinoma European Archives of Oto-Rhino-Laryngology, December 3, 2012

989 Long-term regional control and survival in patients with low-risk, early stage oral tongue cancer managed by partial glossectomy and neck dissection without postoperative radiation Cancer, November 30, 2012

990 MiR-29c suppresses invasion and metastasis by targeting TIAM1 in nasopharyngeal carcinoma Cancer Letters, November 30, 2012

991 Detection of Transcriptionally Active High-risk HPV in Patients With Head and Neck Squamous Cell Carcinoma as Visualized by a Novel E6/E7 mRNA In Situ Hybridization Method American Journal of Surgical Pathology , November 30, 2012

992 Conventional Chondrosarcoma in a Survivor of Rhabdoid Tumor: Enlarging The Spectrum of Tumors Associated With SMARCB1 Germline Mutations American Journal of Surgical Pathology , November 30, 2012

993 Evaluating the impact of patient, tumor, and treatment characteristics on the development of jaw complications in patients treated for oral cancers: A SEER-Medicare analysis Head & Neck, November 30, 2012    Clinical Article

994 Young nasopharyngeal cancer patients with radiotherapy and chemotherapy are most prone to ischemic stroke risk Clinical Otolaryngology, November 30, 2012    Clinical Article

995 Phase II study of sorafenib in combination with cisplatin and 5-fluorouracil to treat recurrent or metastatic nasopharyngeal carcinoma Annals of Oncology, November 29, 2012

996 Dysregulation of the repressive H3K27 trimethylation mark in head and neck squamous cell carcinoma contributes to dysregulated squamous differentiation Clinical Cancer Research, November 29, 2012

997 Detection of Novel Actionable Genetic Changes in Salivary Duct Carcinoma Helps Direct Patient Treatment Clinical Cancer Research, November 29, 2012

998 A Comparison of Three Nonsurgical Treatment Strategies to Preserve the Larynx in Patients With Locally Advanced Larynx Cancer Journal of Clinical Oncology, November 29, 2012

999 DNA copy gains of tumor-related genes in vestibular schwannoma European Archives of Oto-Rhino-Laryngology, November 29, 2012

1000 Tumoral indoleamine 2,3-dioxygenase expression predicts poor outcome in laryngeal squamous cell carcinoma Virchows Archiv, November 29, 2012

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Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

Read the article summary

HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 Treatment of squamous cell carcinoma of the mobile tongue or tongue margins: An interdisciplinary challenge Acta Oncologica, May 23, 2013    Review Article

2 Tea and coffee consumption and risk of oral cavity cancer: Results of a large population-based case-control study, the ICARE study Cancer Epidemiology, April 22, 2013

3 An Oral Cavity Carcinoma Nomogram to Predict Benefit of Adjuvant Radiotherapy JAMA Otolaryngology—Head & Neck Surgery, May 20, 2013

4 Cetuximab: its unique place in head and neck cancer treatment Biologics: targets & therapy, April 24, 2013    Free full text

5 Long-term follow-up of a phase III study comparing radiotherapy with or without weekly oxaliplatin for locoregionally advanced nasopharyngeal carcinoma Annals of Oncology, May 14, 2013

6 Three-phase adaptive dose-painting-by-numbers for head-and-neck cancer: initial results of the phase I clinical trial Radiotherapy & Oncology, May 13, 2013

7 CD8+ and CD4+ tumour infiltrating lymphocytes in relation to human papillomavirus status and clinical outcome in tonsillar and base of tongue squamous cell carcinoma European Journal of Cancer, May 6, 2013

8 Periodontal disease and mouthwash use are risk factors for head and neck squamous cell carcinoma Cancer Causes and Control, April 12, 2013

9 Effects of celecoxib treatment over the AKT pathway in head and neck squamous cell carcinoma Journal of Oral Pathology & Medicine, May 17, 2013

10 Characterization of CACNA2D3 as a putative tumor suppressor gene in the development and progression of nasopharyngeal carcinoma International Journal of Cancer, May 7, 2013

11 Predictive value of HPV in oropharyngeal carcinoma treated with radiotherapy: An updated systematic review and meta-analysis of 30 trials Head & Neck, April 30, 2013

12 Cetuximab/cisplatin and radiotherapy in HNSCC: is there a favorite choice? Central European Journal of Medicine, April 23, 2013

13 Connective tissue growth factor activates pluripotency genes and mesenchymal-epithelial transition in head and neck cancer cells Cancer Research, May 21, 2013

14 Hyperthyroidism and Thyroid Cancer Risk: A Population-based Cohort Study Experimental and Clinical Endocrinology & Diabetes, April 29, 2013

15 Extranodal lymphomas of head and neck with emphasis on NK/T-cell lymphoma, nasal type Journal of Cranio-Maxillofacial Surgery, May 22, 2013

16 Reconstruction of anterior floor of mouth defects by the local mandible myofascial flap following cancer ablation: A pilot study Journal of Plastic, Reconstructive & Aesthetic Surgery, May 20, 2013

17 Pattern of CAIX expression is prognostic for outcome and predicts response to ARCON in patients with laryngeal cancer treated in a phase III randomized trial Radiotherapy & Oncology, May 29, 2013    Review Article

18 Evaluation of hypoxia in a feline model of head and neck cancer using 64Cu-ATSM positron emission tomography/computed tomography BMC Cancer, May 6, 2013    Free full text

19 P53 (Pro72Arg) polymorphism associated with the risk of oral squamous cell carcinoma in gutka, niswar and manpuri addicted patients of Pakistan Oral Oncology , May 20, 2013    Review Article

20 Significant efficacies of neoadjuvant and adjuvant chemotherapy for nasopharyngeal carcinoma by meta-analysis of published literature-based randomized, controlled trials Annals of Oncology, May 9, 2013    Evidence Based Medicine

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncologymore

Other Topics in Oncology

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