Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
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161 Magnetic resonance imaging and ultrasound evaluation of healthy joints in young subjects with severe haemophilia A Haemophilia, March 25, 2013 Clinical Article
162 Variability in platelet- and collagen-binding defects in type 2M von Willebrand disease Haemophilia, March 25, 2013 Clinical Article
163 Monitoring rFVIII prophylaxis dosing using global haemostasis assays Haemophilia, March 25, 2013 Clinical Article
164 Predicting Response to rFVIIa in Neonates With Intractable Bleeding or Severe Coagulation Disturbances Journal of Pediatric Hematology/Oncology, March 25, 2013 Clinical Article
165 Anticoagulant use in patients with cancer associated venous thromboembolism: A retrospective cohort study Thrombosis Research, March 22, 2013 Evidence Based Medicine Clinical Article
166 Blood hypomethylation of inflammatory genes mediates the effects of metal-rich airborne pollutants on blood coagulation Occupational and Environmental Medicine, March 22, 2013 Review Article
167 Protected by nature Effects of strenuous physical exercise on FVIII activity in moderate and mild haemophilia A patients: a pilot study Haemophilia, March 22, 2013 Clinical Article
168 Immune tolerance induction in haemophilia A patients with inhibitors by treatment with recombinant factor VIII: a retrospective non-interventional study Haemophilia, March 22, 2013 Clinical Article
169 Inherited thrombocytopenias frequently diagnosed in adults Journal of Thrombosis and Haemostasis, March 21, 2013 Clinical Article
170 Changes of plasma vWF level in response to the improvement of air quality: an observation of 114 healthy young adults Annals of Hematology, March 19, 2013 Clinical Article
171 Comparison of the inhibitory activity of human TFPI and TFPIβ Journal of Thrombosis and Haemostasis, March 18, 2013 Clinical Article
172 Laboratory testing for bleeding disorders: strategic uses of high and low-yield tests International Journal of Laboratory Hematology, March 18, 2013 Clinical Article
173 Comparison of discriminative indices for iron deficiency anemia and β thalassemia trait in a Brazilian population Hematology, March 14, 2013 Clinical Article
174 Cost-Effectiveness of Additional Catheter-Directed Thrombolysis for Deep Vein Thrombosis Journal of Thrombosis and Haemostasis, March 13, 2013 Clinical Article
175 Activated protein C attenuates pulmonary coagulopathy in patients with acute respiratory distress syndrome Journal of Thrombosis and Haemostasis, March 12, 2013 Clinical Article
176 Predicting post-thrombolysis intracerebral hemorrhage: A systematic review Journal of Thrombosis and Haemostasis, March 12, 2013 Clinical Article
177 Risk factors, antithrombotic treatment and outcome in retinal vein occlusion: an age-related prospective cohort study European Journal of Haematology, March 12, 2013 Clinical Article
178 Response to low-dose desmopressin by a subcutaneous route in children with type 1 von Willebrand disease Hematology, March 12, 2013 Clinical Article
179 Alloantibodies in previously untreated hemophilia A patients: the role of environmental factors Hematology, March 12, 2013 Clinical Article
180 The concurrent use of antithrombotic therapies and the risk of bleeding in patients with atrial fibrillation Thrombosis and Haemostasis, March 12, 2013 Clinical Article
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 Management and outcomes for patients with TTP: Analysis of 100 cases at a single institution American Journal of Hematology, April 29, 2013
2 Anticoagulation for prevention and treatment of cancer-related venous thromboembolism British Journal of Haematology, April 9, 2013
3
Adherence to anticoagulant treatment with dabigatran in a real-world setting
Journal of Thrombosis and Haemostasis, April 19, 2013
Exclusive Author Commentary
4 Impact of a venous thromboembolism (VTE) prophylaxis smart order set: Improved compliance, fewer events American Journal of Hematology, April 8, 2013
5 Bleeding risk in warfarinized patients with a therapeutic INR: the effect of low factor IX levels Journal of Thrombosis and Haemostasis, April 18, 2013
6 Intracranial haemorrhage in von Willebrand disease: a report on six cases Haemophilia, April 23, 2013
7 Advances in megakaryocytopoiesis and thrombopoiesis: from bench to bedside British Journal of Haematology, April 25, 2013 Review Article
8 ADAMTS13 unbound to larger von Willebrand factor multimers in cryosupernatant: implications for selection of plasma preparations for thrombotic thrombocytopenic purpura treatment Transfusion, April 10, 2013
9 Venous thromboembolism in adults treated for acute lymphoblastic leukaemia: Effect of fresh frozen plasma supplementation Thrombosis and Haemostasis, April 23, 2013
10 The predictive ability of bleeding risk stratification models in very old patients on VKA treatment for venous thromboembolism Results of the Prospective Collaborative EPICA study Journal of Thrombosis and Haemostasis, April 15, 2013
11 FcRIIa proteolysis as a diagnostic biomarker for heparin-induced thrombocytopenia Journal of Thrombosis and Haemostasis, April 3, 2013
12 Unresponsive thrombotic thrombocytopenic purpura in critically ill adults Intensive Care Medicine, April 5, 2013
13 Statin Therapy and Levels of Hemostatic Factors in a Healthy Population: the Multi-Ethnic Study of Atherosclerosis Journal of Thrombosis and Haemostasis, April 11, 2013
14 Post-thrombotic syndrome: a clinical review Journal of Thrombosis and Haemostasis, March 8, 2013 Review Article
15 Product-dependent anti-factor VIII antibodies Haemophilia, April 25, 2013
16 Anticoagulant use in patients with cancer associated venous thromboembolism: A retrospective cohort study Thrombosis Research, March 22, 2013 Evidence Based Medicine
17 Plasma concentration of protein Z and protein Z-dependent protease inhibitor in patients with haemophilia A Thrombosis Research, April 2, 2013 Evidence Based Medicine
18 Whole blood clots are more resistant to lysis than plasma clots - greater efficacy of rivaroxaban Thrombosis Research, April 2, 2013
19 Platelet size for distinguishing between inherited thrombocytopenias and immune thrombocytopenia: a multicentric, real life study British Journal of Haematology, April 26, 2013 Review Article
20 Successful percutaneous coronary intervention in a patient with combined deficiency of FV and FVIII due to novel compound heterozygous mutations in LMAN1 Haemophilia, April 11, 2013
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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